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2801por Evans, John P., Zeng, Cong, Carlin, Claire, Lozanski, Gerard, Saif, Linda J., Oltz, Eugene M., Gumina, Richard J., Liu, Shan-Lu“…Neutralizing antibody titers against all variants, especially the Delta variant, declined dramatically from four weeks to six months post-second mRNA vaccine dose. …”
Publicado 2021
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2802por LI, Ling Hua, TU, Hong Wei, LIANG, Dan, WEN, Chun Yan, LI, An An, LIN, Wei Yin, HU, Ke Qi, HONG, Wen Shan, LI, Yue Ping, SU, Juan, ZHAO, San Tao, LI, Wei, YUAN, Run Yu, ZHOU, Ping Ping, HU, Feng Yu, TANG, Xiao Ping, KE, Chang Wen, KE, Bi Xia, CAI, Wei Ping“…Although a decreasing trend in NAb titer was observed in many cases, the NAb level was generally still protective. …”
Publicado 2021
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2803“…All manufacturing approaches tend to follow the generally accepted dogma of increasing titer since it directly increases manufacturing output. …”
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2804por Ferrari, Alessandro, Cassaniti, Irene, Sammartino, Josè Camilla, Mortellaro, Cristina, Del Fante, Claudia, De Vitis, Simona, Barone, Eugenio, Troletti, Daniela, Prati, Federica, Baldanti, Fausto, Percivalle, Elena, Cesare, Perotti“…The units were then under treatment with Mirasol PRT. The infectious titers were determined before and after treatment with an in house microtitration assay on Vero E6 cells. …”
Publicado 2022
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2805por Romero-Pinedo, Salvador, Quesada, Marina, Horndler, Lydia, Álvarez-Fernández, Stela, Olmo, Asunción, Abia, David, Alarcón, Balbino, Delgado, Pilar“…We also found that, in the elderly, antibody titers negatively correlate with the age of the donor but, also, that antibody titers remain stable for at least 6 months after complete vaccination. …”
Publicado 2022
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2806por Gupta, Divya, Ahmed, Farhan, Tandel, Dixit, Parthasarathy, Haripriya, Vedagiri, Dhiviya, Sah, Vishal, Krishna Mohan, B., Khan, Rafiq Ahmad, Kondiparthi, Chiranjeevi, Savari, Prabhudas, Jain, Sandesh, Reddy, Shashikala, Kumar, Jerald Mahesh, Khan, Nooruddin, Harshan, Krishnan Harinivas“…Herein, we demonstrate that equines hyper-immunized with chemically inactivated SARS-CoV-2 elicited high antibody titers with a strong virus-neutralizing potential, and F(ab’)(2) fragments purified from them displayed strong neutralization potential against five different SARS-CoV-2 variants. …”
Publicado 2022
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2807por Kato, Hideaki, Miyakawa, Kei, Ohtake, Norihisa, Yamaoka, Yutaro, Yajima, Satoshi, Yamazaki, Etsuko, Shimada, Tomoko, Goto, Atsushi, Nakajima, Hideaki, Ryo, Akihide“…SP IgG titer was negatively correlated with age and alcohol consumption. …”
Publicado 2022
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2808BNT162b2-elicited neutralization of Delta plus, Lambda, Mu, B.1.1.519, and Theta SARS-CoV-2 variantspor Liu, Jianying, Liu, Yang, Xia, Hongjie, Zou, Jing, Weaver, Scott C., Swanson, Kena A., Cai, Hui, Cutler, Mark, Cooper, David, Muik, Alexander, Jansen, Kathrin U., Sahin, Ugur, Xie, Xuping, Dormitzer, Philip R., Shi, Pei-Yong“…Geometric mean plaque reduction neutralization titers against Delta-AY.1, Delta-AY.2, and Mu viruses are slightly lower than against USA-WA1/2020, but all sera neutralize the variant viruses to titers of ≥80, and neutralization titers against the Delta-∆144, Lambda, B.1.1.519 and Theta variants not significantly reduced relative to those against USA-WA1/2020. …”
Publicado 2022
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2809por Fong, Youyi, McDermott, Adrian B., Benkeser, David, Roels, Sanne, Stieh, Daniel J., Vandebosch, An, Gars, Mathieu Le, Van Roey, Griet A., Houchens, Christopher R., Martins, Karen, Jayashankar, Lakshmi, Castellino, Flora, Amoa-Awua, Obrimpong, Basappa, Manjula, Flach, Britta, Lin, Bob C., Moore, Christopher, Naisan, Mursal, Naqvi, Muhammed, Narpala, Sandeep, O’Connell, Sarah, Mueller, Allen, Serebryannyy, Leo, Castro, Mike, Wang, Jennifer, Petropoulos, Christos J., Luedtke, Alex, Hyrien, Ollivier, Lu, Yiwen, Yu, Chenchen, Borate, Bhavesh, van der Laan, Lars W. P., Hejazi, Nima S., Kenny, Avi, Carone, Marco, Wolfe, Daniel N., Sadoff, Jerald, Gray, Glenda E., Grinsztejn, Beatriz, Goepfert, Paul A., Little, Susan J., de Sousa, Leonardo Paiva, Maboa, Rebone, Randhawa, April K., Andrasik, Michele P., Hendriks, Jenny, Truyers, Carla, Struyf, Frank, Schuitemaker, Hanneke, Douoguih, Macaya, Kublin, James G., Corey, Lawrence, Neuzil, Kathleen M., Carpp, Lindsay N., Follmann, Dean, Gilbert, Peter B., Koup, Richard A., Donis, Ruben O.“…Comparison of the vaccine efficacy by ID50 titer curves for ENSEMBLE-US, the COVE trial of the mRNA-1273 vaccine, and the COV002-UK trial of the AZD1222 vaccine supported consistency of the ID50 titer correlate of protection across trials and vaccine types.…”
Publicado 2022
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2810por Oliveira-Silva, Joana, Reis, Teresa, Lopes, Cristiana, Batista-Silva, Ricardo, Ribeiro, Ricardo, Marques, Gilberto, Pacheco, Vania, Rodrigues, Tiago, Afonso, Alexandre, Pinheiro, Vítor, Araújo, Lucília, Rodrigues, Fernando, Antunes, Isabel“…A linear mixed-effects model supported that female gender, younger age groups, and being seropositive prevaccination maintained higher antibody titers. Curves became tighter with time progression, although titers from seropositive subjects decrease at a slower rate than seronegative ones. …”
Publicado 2022
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2811por Pradenas, Edwards, Ubals, Maria, Urrea, Víctor, Suñer, Clara, Trinité, Benjamin, Riveira-Muñoz, Eva, Marfil, Silvia, Ávila-Nieto, Carlos, Rodríguez de la Concepción, María Luisa, Tarrés-Freixas, Ferran, Laporte, Josep, Ballana, Ester, Carrillo, Jorge, Clotet, Bonaventura, Mitjà, Oriol, Blanco, Julià“…BACKGROUND: Evidence on the determinants of the magnitude of humoral responses and neutralizing titers in individuals with mild COVID-19 is scarce. …”
Publicado 2022
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2812por Kotsiou, Ourania S., Vavougios, George D., Papagiannis, Dimitrios, Matsiatsiou, Elena, Avgeri, Dimitra, Fradelos, Evangelos C., Siachpazidou, Dimitra I., Perlepe, Garifallia, Miziou, Angeliki, Kyritsis, Athanasios, Gogou, Eudoxia, Kalampokas, Serafim, Kalantzis, Georgios, Kotsios, Vaios S., Gourgoulianis, Konstantinos I.“…Higher antibody titers were measured in infected vaccinated individuals than in infected unvaccinated ones.…”
Publicado 2022
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2813por Zimmerman, Ofer, Altman Doss, Alexa Michelle, Kaplonek, Paulina, Liang, Chieh-Yu, VanBlargan, Laura A., Chen, Rita E., Monroy, Jennifer Marie, Wedner, H. James, Kulczycki, Anthony, Mantia, Tarisa L., O’Shaughnessy, Caitlin C., Davis-Adams, Hannah G., Bertera, Harry L., Adams, Lucas J., Raju, Saravanan, Zhao, Fang R., Rigell, Christopher J., Dy, Tiffany Biason, Kau, Andrew L., Ren, Zhen, Turner, Jackson S., O’Halloran, Jane A., Presti, Rachel M., Fremont, Daved H., Kendall, Peggy L., Ellebedy, Ali H., Alter, Galit, Diamond, Michael S.“…The immunoglobulin replacement products tested have low anti-spike and receptor-binding domain (RBD) titers and neutralizing activity. In coronavirus disease 2019 (COVID-19)-naive individuals with PAD, anti-spike and RBD titers increase after mRNA vaccination but wane by 90 days. …”
Publicado 2022
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2814por Fathi, Anahita, Dahlke, Christine, Krähling, Verena, Kupke, Alexandra, Okba, Nisreen M. A., Raadsen, Matthijs P., Heidepriem, Jasmin, Müller, Marcel A., Paris, Grigori, Lassen, Susan, Klüver, Michael, Volz, Asisa, Koch, Till, Ly, My L., Friedrich, Monika, Fux, Robert, Tscherne, Alina, Kalodimou, Georgia, Schmiedel, Stefan, Corman, Victor M., Hesterkamp, Thomas, Drosten, Christian, Loeffler, Felix F., Haagmans, Bart L., Sutter, Gerd, Becker, Stephan, Addo, Marylyn M.“…Both binding and neutralizing anti-MERS-CoV antibody titers increase substantially in all participants and exceed maximum titers observed after primary immunization more than 10-fold. …”
Publicado 2022
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2815por Munz, Clara Marie, Kreher, Henriette, Erdbeer, Alexander, Richter, Stefanie, Westphal, Dana, Yi, Buqing, Behrendt, Rayk, Stanke, Nicole, Lindel, Fabian, Lindemann, Dirk“…Depending on the type of virus, produced titers were 2- to 10-fold higher compared with those obtained by PEI transfection.…”
Publicado 2022
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2816“…The results of this study support strong associations between titers of food-specific IgG antibodies and intestinal permeability biomarkers in adults, to the extent that the presence of multiple IgG antibodies to food, and increasing IgG food titers, can be considered indicative of increased antibodies to LPS and occludin. …”
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2817por Leon, Ariel E., Garelle, Della, Hartwig, Airn, Falendysz, Elizabeth A., Ip, Hon S., Lankton, Julia S., Tretten, Tyler N., Spraker, Terry R., Bowen, Richard, Rocke, Tonie E.“…Vaccination and boosting of 15 BFF with purified SARS-CoV-2 S1 subunit protein produced a nearly 150-fold increase in mean antibody titers compared to pre-vaccination titers. Serum antibody responses were highest in young animals, but in all vaccinees, antibody response declined rapidly. …”
Publicado 2022
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2818“…This titer could be further raised by codon optimization of auaA and by introducing the mevalonate pathway into the production strain. …”
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2819por Yang, Meichen, Meng, Hao, Li, Xianglai, Wang, Jia, Shen, Xiaolin, Sun, Xinxiao, Yuan, Qipeng“…As a result, the titer was improved to 559.4 mg/L in shake flasks and to 3.89 g/L in fed-batch fermentation. …”
Publicado 2022
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2820por Renna, Laura V., Bertani, Fabio, Podio, Alessandro, Boveri, Sara, Carrara, Matteo, Pinton, Arianna, Milani, Valentina, Spuria, Giovanni, Nizza, Angelica F., Basilico, Sara, Dubini, Carola, Cerri, Ambra, Menicanti, Lorenzo, Corsi-Romanelli, Massimiliano M., Malavazos, Alexis E., Cardani, Rosanna“…To date, little is known about the durability and kinetics of antibody titers months after receiving a booster dose. In this work, we studied the dynamic of anti-Trimeric Spike (anti-TrimericS) IgG titer in the healthcare worker population of a large academic hospital in Northern Italy, in those who had received two vaccine doses plus a booster dose. …”
Publicado 2023
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