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621por Rouers, Angeline, Chng, Melissa Hui Yen, Lee, Bernett, Rajapakse, Menaka P., Kaur, Kaval, Toh, Ying Xiu, Sathiakumar, Durgalakshmi, Loy, Thomas, Thein, Tun-Linn, Lim, Vanessa W.X., Singhal, Amit, Yeo, Tsin Wen, Leo, Yee-Sin, Vora, Kalpit A., Casimiro, Danilo, Lim, Bing, Tucker-Kellogg, Lisa, Rivino, Laura, Newell, Evan W., Fink, Katja“…This does not translate into long-term antibody titers, since neutralizing titers after 6 months correlate with percentages of specific memory B cells, but not with acute plasmablast activation. …”
Publicado 2021
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623“…Assessments of serological markers revealed a high titer of antibodies against hepatitis B core antigen (anti-HBcAg antibodies), an extremely high titer (1000 mIU/mL) of hepatitis B surface antibodies (anti-HBsAg antibodies, anti-HBs) and absence of detectible HBsAg. …”
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624por Fanning, Stacey L., Korngold, Robert, Yang, Zheng, Goldgirsh, Kira, Park, Steven, Zenreich, Joshua, Baker, Melissa, McKiernan, Phyllis, Tan, Ming, Zhang, Bingsong, Donato, Michele L., Perlin, David S.“…A Phase IIa clinical trial at our institution using high neutralizing titer convalescent plasma transfer gave us the unique opportunity to study the elevations of correlates in the first 10 days after infusion. …”
Publicado 2021
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625por Mitani, Akihisa, Horie, Takeshi, Yokoyama, Rin, Nakano, Yuki, Hamada, Kensuke, Inoue, Yukiko, Saito, Minako, Ishii, Takashi, Sunohara, Mitsuhiro, Takahashi, Ryota, Usui, Tomoko, Emoto, Noriko, Nishimoto, Nahoko, Murano, Yoko, Okazaki, Sachiko, Tateishi, Shoko, Iwasawa, Kuniaki, Yao, Atsushi, Kurano, Makoto, Yatomi, Yutaka, Yanagimoto, Shintaro“…METHODS: From June 2020, we recruited 10,039 participants to the project named the University of Tokyo COVID-19 Antibody Titer Survey (UT-CATS), and measured iFlash-SARS-CoV-2 IgM and IgG (YHLO IgM and IgG) titers in the collected serum. …”
Publicado 2022
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626por Yang, Li, Xu, Qiang, Yang, Bin, Li, Jiayu, Dong, Rong, Da, Jingjing, Ye, Zhixu, Xu, Yongjie, Zhou, Hourong, Zhang, Xiangyan, Liu, Lin, Zha, Yan, Yu, Fuxun“…This system enabled a quantitative study of rSARS-CoV-2-N IgG antibody titers in COVID-19 patients, the occurrence of higher IgG antibody titers were found to be correlated with more severe cases. …”
Publicado 2021
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627por Nguyen, Dung, Xiao, Julie, Simmonds, Peter, Lamikanra, Abigail, Odon, Valerie, Ratcliff, Jeremy, Townsend, Alain, Roberts, David J, Harvala, Heli“…Plasma samples collected in 2020 before emergence of variants showed reduced titers against the Alpha variants, and both sets of samples demonstrated significantly reduced titers against Beta. …”
Publicado 2021
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628por Saker, Kahina, Escuret, Vanessa, Pitiot, Virginie, Massardier-Pilonchéry, Amélie, Paul, Stéphane, Mokdad, Bouchra, Langlois-Jacques, Carole, Rabilloud, Muriel, Goncalves, David, Fabien, Nicole, Guibert, Nicolas, Fassier, Jean-Baptiste, Bal, Antonin, Trouillet-Assant, Sophie, Trabaud, Mary-Anne“…With assays allowing BAU/mL correction, Ab titers were correlated (Pearson correlation coefficient, ρ, range: 0.85–0.94). …”
Publicado 2022
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629por Liu, Fei, Feng, Canbin, Xu, Shiqi, Wu, Qiang, Tang, Jian, Chen, Yan, Xu, Ruisheng, Chen, Fuliang, Gao, Ni, Xu, Zhengzheng, Gu, Shihui, Lan, Yang, Zhou, Haibo, Hu, Xinde, Wang, XiaojingEnlace del recurso
Publicado 2022
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630“…Greater titer variation was observed after oral versus intrathoracic infection, suggesting that the midgut barrier contributes to titer variability. …”
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631por Somasundaram, Sivachandiran, Jeong, Jaehoon, Kumaravel, Ashokkumar, Hong, Soon HoEnlace del recurso
Publicado 2021
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632por Huang, Yunda, Zhang, Lily, Eaton, Amanda, Mkhize, Nonhlanhla N., Carpp, Lindsay N., Rudnicki, Erika, DeCamp, Allan, Juraska, Michal, Randhawa, April, McDermott, Adrian, Ledgerwood, Julie, Andrew, Philip, Karuna, Shelly, Edupuganti, Srilatha, Mgodi, Nyaradzo, Cohen, Myron, Corey, Lawrence, Mascola, John, Gilbert, Peter B., Morris, Lynn, Montefiori, David C.“…Our results may be applied to future studies of other bnAbs and bnAb combinations to maximize resource efficiency in serum neutralization titer measurement.…”
Publicado 2021
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633por Sun, Xiaoxiao, Xu, Linling, Xia, Ying, Luo, Shuoming, Lin, Jian, Xiao, Yang, Huang, Gan, Li, Xia, Xie, Zhiguo, Zhou, Zhiguang“…RESULTS: 1) rs3806265 was associated with glutamic acid decarboxylase antibody (GADA) titers (P = 0.02), and patients with the CC genotype had higher GADA titers than patients with the TT genotype. 2) rs4612666 was also associated with GADA titers (P=0.041). …”
Publicado 2022
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634por Takita, Mumon, Yoshida, Toru, Tsuchida, Tomoya, Nakagama, Yu, Kido, Yasutoshi, Suzuki, Shotaro, Imamura, Mitsuru, Kawahata, Kimito, Shimizu, Goji, Yoshida, Hideki, Morikawa, Daiki, Kawaguchi, Takeshi, Fujii, Shuichi, Tsukuda, Jumpei, Motohashi, Takako, Fujitani, Shigeki“…Recently, immune response to coronavirus disease (COVID-19) has attracted attention where an association between higher antibody titer and worsening disease severity has been reported. …”
Publicado 2022
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635por Compagnone, Mirco, Pinto, Eleonora, Salvatori, Erika, Lione, Lucia, Conforti, Antonella, Marchese, Silvia, Ravà, Micol, Ryan, Kathryn, Hall, Yper, Rayner, Emma, Salguero, Francisco J., Paterson, Jemma, Iannacone, Matteo, De Francesco, Raffaele, Aurisicchio, Luigi, Palombo, FabioEnlace del recurso
Publicado 2022
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636por Connelly, Guinevere G., Kirkland, Orville O., Bohannon, Seven, Lim, Daniel C., Wilson, Robert M., Richards, Edward J., Tay, Dousabel M., Jee, Hyuk, Hellinger, Riley D., Hoang, Ngoc K., Hao, Liang, Chhabra, Arnav, Martin-Alonso, Carmen, Tan, Edward K.W., Koehler, Angela N., Yaffe, Michael B., London, Wendy B., Lee, Pui Y., Krammer, Florian, Bohannon, Robert C., Bhatia, Sangeeta N., Sikes, Hadley D., Li, Hojun“…Neutralizing antibody (NAb) titer is a key biomarker of protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but point-of-care methods for assessing NAb titer are not widely available. …”
Publicado 2022
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637por Kurashima, Kazuyoshi, Numano, Tsuyoshi, Yoshino, Atsuki, Osawa, Akiko, Takaku, Yotaro, Kagiyama, Naho, Yanagisawa, Tsutomu“…The factors influencing titer of antibodies against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) among healthcare workers for coronavirus disease 2019 (COVID-19) is unclear. …”
Publicado 2022
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638por Sullivan, David J., Franchini, Massimo, Joyner, Michael J., Casadevall, Arturo, Focosi, Daniele“…Lessons learnt from previous usage of CCP suggests focusing on early outpatients and immunocompromised recipients, with high neutralizing antibody titer units. Here, we systematically review Omicron-neutralizing plasma activity data, and report that approximately 47% (424/902) of CCP samples from unvaccinated pre-Omicron donors neutralizes Omicron BA.1 with a very low geometric mean of geometric mean titers for 50% neutralization GM(GMT(50)) of ~13, representing a > 20-fold reduction from WA-1 neutralization. …”
Publicado 2022
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639“…In the 5-L bioreactor, through the establishment of strategies for glucose and citric acid feeding and dissolved oxygen regulation, the cholesterol production was further increased to 339.87 mg/l, which was 734% higher than that in the original medium. This is the highest titer of cholesterol produced by microorganisms currently reported. …”
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640por Galloway, Darrell R., Nguyen, Nguyen X., Li, Jiahui, Houston, Nicholas, Gregersen, Gage, Williamson, E. Diane, Falkenberg, Frank W., Herron, James N., Hale, J. Scott“…Importantly, enhanced germinal center Tfh and B cell responses correlated with long-lasting and high F1V-specific antibody titers and more robust antibody recall responses to F1V re-exposure. …”
Publicado 2022
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