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541por Dai, Guanhai, Tong, Yeling, Chen, Xuan, Ren, Zeming, Ying, Xuhua, Yang, Feng, Chai, Kequn“…These results are consistent with those of IHC. The TUNEL assay results indicated that apoptotic-positive cells significantly increased in the myricanol-treated tumor tissues compared with the cells of the vehicle control group (p < 0.01 to 0.001). …”
Publicado 2015
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542por Kubo, Nobuteru, Noda, Shin-ei, Takahashi, Akihisa, Yoshida, Yukari, Oike, Takahiro, Murata, Kazutoshi, Musha, Atsushi, Suzuki, Yoshiyuki, Ohno, Tatsuya, Takahashi, Takeo, Nakano, Takashi“…Apoptosis and senescence were evaluated by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) staining and senescence-associated β-galactosidase (SA-β-gal) staining, respectively. …”
Publicado 2015
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543por Veres, Gábor, Hegedűs, Péter, Barnucz, Enikő, Zöller, Raphael, Klein, Stephanie, Schmidt, Harald, Radovits, Tamás, Korkmaz, Sevil, Karck, Matthias, Szabó, Gábor“…DNA strand breaks were assessed by TUNEL-method, mRNA expressions (caspase-3, bax, bcl-2, eNOS) by quantitative real-time PCR, proteins by Western blot analysis and the expression of CD-31 by immunochemistry. …”
Publicado 2015
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544“…Histochemistry, TUNEL, and echocardiography were carried out to evaluate cell engraftment, apoptosis, angiogenesis, scar formation, and cardiac functional recovery. …”
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545“…The activities of GPX (glutathione peroxidase) and SOD (superoxide dismutase) were unaltered in diabetic rats. TUNEL assay revealed increased apoptotic cell death in the liver. …”
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546por Zhou, Mingjie, Ren, Huanhuan, Han, Jichun, Wang, Wenjuan, Zheng, Qiusheng, Wang, Dong“…However, the pretreatment reduced myocardial infarct size and TUNEL-positive cell rate, as well as decreased the levels of cleaved caspase-3, cytoplasm cytochrome C, CK, LDH, MDA, and TNF-α. …”
Publicado 2015
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547por Dharmapatni, Anak A. S. S. K., Cantley, Melissa D., Marino, Victor, Perilli, Egon, Crotti, Tania N., Smith, Malcolm D., Haynes, David R.“…Immunohistochemistry was used to detect XIAP protein. TUNEL was performed to identify apoptotic cells. …”
Publicado 2015
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548por LIAN, FAN, WANG, YU, XIAO, YOUJUN, WU, XIWEN, XU, HANSHI, LIANG, LIUQIN, YANG, XIUYAN“…The activation of FXR ameliorated hepatocyte apoptosis, as demonstrated by TUNEL analysis and downregulation of the Fas/Fas ligand, tumor necrosis factor-related apoptosis-inducing ligand and caspase-3. …”
Publicado 2015
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549por Babaee, Abdolreza, Eftekhar-Vaghefi, Seyed Hassan, Asadi-shekaari, Majid, Shahrokhi, Nader, Soltani, Samereh Dehghani, Malekpour-Afshar, Reza, Basiri, Mohsen“…Furthermore, based on TUNEL results, melatonin treatment considerably reduced the number of apoptotic cells (P<0.05). …”
Publicado 2015
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550por Elvas, Filipe, Vangestel, Christel, Rapic, Sara, Verhaeghe, Jeroen, Gray, Brian, Pak, Koon, Stroobants, Sigrid, Staelens, Steven, wyffels, Leonie“…Radioactivity in the tumors positively correlated with cleaved caspase-3 (r = 0.85, p < 0.001) and TUNEL (r = 0.92, p < 0.001) staining. CONCLUSION: [(99m)Tc]Duramycin can be used to detect early chemotherapy-induced tumor cell death, and thus, may be a prospective candidate for clinical SPECT imaging of tumor response to therapy. …”
Publicado 2015
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551“…Apoptosis was induced by H(2)O(2), and evaluated by TUNEL assay. The effect of cardiomyocyte apoptosis on gene expression of miR-137 was evaluated by qRT-PCR. …”
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552“…Immunohistochemical staining and real-time PCR were used to detect the protein and mRNA expression levels, and TUNEL was used to assess lens epithelial cells apoptosis. …”
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553“…CONCLUSIONS: From our in vivo data in the rat model, the observed decreases in the TUNEL staining suggest a potential therapeutic benefit of the CM in ameliorating PAH-mediated lung tissue damage. …”
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554“…Furthermore, T helper 1-mediated proin-flammatory cytokines were suppressed by losartan, and gut permeability was largely preserved. TUNEL staining revealed reduced IEC apoptosis in the losartan-treated mice. …”
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555por Farhadi, Farrokh, Jahanpour, Salar, Hazem, Kameliya, Aghbali, Amirala, Baradran, Behzad, Vahid Pakdel, Seyyed Mahdi“…MTTassay (MicrocultureTetrazolium Assay) was carried out to evaluate the cytotoxicity of GFJ on KB cells. Furthermore, TUNEL(Terminal deoxynucleotidyltransferase-mediated dUTP nick end labeling)and DNA fragmentation tests were performed to determine if GFJ is able to induce apoptosis in KB cells. …”
Publicado 2015
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556por Zhao, Jing, Mysona, Barbara A., Qureshi, Azam, Kim, Lily, Fields, Taylor, Gonsalvez, Graydon B., Smith, Sylvia B., Bollinger, Kathryn E.“…RESULTS: N-methyl-D-aspartate induced a significant increase in TUNEL-positive nuclei and a dose-dependent loss of RGCs. …”
Publicado 2016
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557por Bouderlique, Thibault, Vuppalapati, Karuna K, Newton, Phillip T, Li, Lei, Barenius, Björn, Chagin, Andrei S“…Cell death was evaluated by terminal deoxy-nucleotidyl-transferase-mediated deoxy-UTP nick end labelling (TUNEL) and by immunostaining of cleaved caspases. …”
Publicado 2016
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558por Lu, Yang, Wen, Jun, Chen, DaPeng, Wu, LingLing, Li, QingGang, Xie, Yuansheng, Wu, Di, Liu, Xiaoluan, Chen, XiangMei“…Immunohistochemical analysis of PCNA and KI67, and TUNEL staining were used to detect cell proliferation and apoptosis, respectively. …”
Publicado 2015
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559“…Twelve weeks later, all of the animals were sacrificed and knee joints were evaluated with histological, immunohistochemical, and TUNEL analyses. Mice that received a HFD had significantly greater body weights than the control mice and also exhibited features consistent with knee OA. …”
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560“…Apoptosis was assessed by TUNEL and detection of DNA fragmentation. The levels of mRNA and protein were determined for Bcl-2, Bax, caspase-3, and PARP. …”
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