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  1. 1141
    “…The hallmarks of inflammation, apoptosis and energy metabolism dysfunction were detected by histological and ultrastructural examination, qRT-PCR, Western blotting and terminal deoxynucleotidyl transferase-mediated dUTP nick endlabeling (TUNEL) assay. RESULTS: The level of serum inflammatory markers were increased with MG infection. …”
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    Antagonistic Effects Of Baicalin On Mycoplasma gallisepticum-Induced Inflammation And Apoptosis By Restoring Energy Metabolism In The Chicken Lungs
  2. 1142
    “…Terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) analysis revealed that 60% of mutant nuclei possessed DNA nicks and breaks, whereas in the wild type only 2% of the nuclei were TUNEL-positive. …”
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    ATR, a DNA Damage Signaling Kinase, Is Involved in Aluminum Response in Barley
  3. 1143
    “…Changes in salivary (99m)Tc pertechnetate excretion were followed by SPECT and TUNEL assays were performed. The body and SG weights were similar in the AdMSCs and sham groups. …”
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    Adipose-derived mesenchymal stem cells regenerate radioiodine-induced salivary gland damage in a murine model
  4. 1144
    “…Inflammation and apoptosis were examined by histology (Hematoxylin and Eosin (H&E) staining and Nissl staining, TUNEL assays, and immunofluorescence), Western blotting (from whole tissue protein for iNOS/p-p65/Bax/Bcl-2), and ex vivo ELISA (for TNFα/IL-1β/IL-6/IL-10). …”
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    Progranulin deficiency exacerbates spinal cord injury by promoting neuroinflammation and cell apoptosis in mice
  5. 1145
    “…After LIP, full-field electroretinograms (ERG) and spectral-domain optical coherence tomography (SD-OCT) were obtained longitudinally, and reactive-Iba-1(+)monocytic cells, TUNEL(+) cells and S-opsin(+) cone outer segments were examined up to 7 days. …”
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    Topical Brimonidine or Intravitreal BDNF, CNTF, or bFGF Protect Cones Against Phototoxicity
  6. 1146
    “…Propidium iodide (PI) staining, TUNEL assay, measurement of lactate dehydrogenase (LDH) release and IL-1β ELISA were used to analysis pyroptosis between hydrogen-supplemented or normal culture medium. …”
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    Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway
  7. 1147
    “…This ischemia time also induced persistent cell death (TUNEL) throughout observation for 5 weeks with a peak at 6 h and progressing kidney atrophy beginning 7 d after ischemia. …”
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    “Point of no return” in unilateral renal ischemia reperfusion injury in mice
  8. 1148
    “…Besides, the results of in vivo imaging and following IHC and TUNEL analysis were in accordance with cellular experiments, indicating that AOAA sensitizes colon cancer cells to OXA via exaggerating intrinsic apoptosis. …”
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    Aminooxyacetic acid (AOAA) sensitizes colon cancer cells to oxaliplatin via exaggerating apoptosis induced by ROS
  9. 1149
    “…DNA fragmentation was also significantly reduced, with 6.9 ± 1.4% TUNEL+ cells in HIE+JWH133 and 12.9 ± 2.2% in HIE+Hypothermia + JWH133 vs. 16.6 ± 1.9% in HIE alone. …”
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    Anti-apoptotic and Immunomodulatory Effect of CB2 Agonist, JWH133, in a Neonatal Rat Model of Hypoxic-Ischemic Encephalopathy
  10. 1150
    “…The results of tissue pathology and TUNEL assay showed that ASX protects against OTA-induced myocardial injury. …”
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    Astaxanthin Protects Ochratoxin A-Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway
  11. 1151
    “…However, the positive staining rates of TUNEL and the tumor necrosis rates were significantly increased (p<0.05), and HE staining also revealed higher necrosis rates. …”
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    Improved ADM Penetration Distance and Therapeutic Efficiency in a Rabbit VX2 Liver Cancer Model by Relaxin Infusion Combined with Transcatheter Chemoembolization Through Hepatic Artery
  12. 1152
    “…However, these TUNEL positive cells were mainly confined to the scleral region adjacent to the TM. …”
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    Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork
  13. 1153
    “…A decrease in the number of apoptotic cells using TUNEL assays in the examined samples was observed with increasing disease progression. …”
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    Morphological and functional alterations of the prostate tissue during clinical progression in hormonally-naïve, hormonally-treated and castration-resistant patients with metastatic prostate cancer
  14. 1154
    “…Then, vitro studies including CCK-8 assay, scratch wound healing assay, and TUNEL assay were performed to evaluate the effects of mannose on A549 cells, and an animal model was established to evaluate the antitumoural effect of mannose on NSCLC in vivo. …”
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    Mannose Impairs Lung Adenocarcinoma Growth and Enhances the Sensitivity of A549 Cells to Carboplatin
  15. 1155
    “…Mitochondrial apoptotic signaling and PARP/NF-κB inflammatory signaling were evaluated 24 h after CCI, and apoptotic cell death, neutrophil infiltration, and astrocyte and microglial activation were determined by TUNEL and immunofluorescent staining 3 days after CCI. …”
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    Antiapoptotic and Anti-Inflammatory Effects of CPCGI in Rats with Traumatic Brain Injury
  16. 1156
    “…The effects of intramuscular injection of ADSC-CM on cardiac function, cardiac apoptosis, and fibrosis examined by echocardiography, Evans blue/TTC staining, TUNEL assay, and Masson's trichrome staining in I/R-treated mice. …”
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    Conditioned medium from adipose-derived stem cells attenuates ischemia/reperfusion-induced cardiac injury through the microRNA-221/222/PUMA/ETS-1 pathway
  17. 1157
    “…There was a reduction in apoptosis by TUNEL on follicles, corpora lutea, and collagen type III. …”
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    Pretreatment with melatonin improves ovarian tissue cryopreservation for transplantation
  18. 1158
    “…Interestingly, PI3K inhibitor, Wortmannin, blocked PI3K/AKT pathway and depleted the membrane GULT4, and further promoted apoptosis showed by TUNEL staining, flow cytometer, western blot of cleaved caspase 3, BAX and BCL2 expression. …”
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    DRD4 Mitigates Myocardial Ischemia/Reperfusion Injury in Association With PI3K/AKT Mediated Glucose Metabolism
  19. 1159
    “…Molecular (real time PCR) and histological (immunohistochemistry, immunofluorescence, TUNEL assay) techniques were applied to the eyes of all experimental groups collected at 6, 12, 24, and 48 h, and 6 days after birth. …”
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    Hypothermic Shock Applied After Perinatal Asphyxia Prevents Retinal Damage in Rats
  20. 1160
    “…Apoptosis was observed by TUNEL staining and flow cytometry. Western blotting was used for the analysis of apoptosis-associated proteins Bax, Bcl-2, cleaved (C)-caspase3, total-caspase3, p53 and phosphorylated p53. …”
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    Isoquercitrin protects HUVECs against high glucose-induced apoptosis through regulating p53 proteasomal degradation
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