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  1. 141
    “…After completing the administration, tissues were isolated for Klüver-Barrera and the terminal deoxynucleotidyl transferase biotin-dUTP nick end labelling (TUNEL) staining. RESULTS: In the immediate-treatment group, cognitive functions were preserved in the citicoline-treated group, and WM damage and TUNEL-positive cells differed significantly between the citicoline- and PBS-treated animals. …”
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    Citicoline Protects Against Cognitive Impairment in a Rat Model of Chronic Cerebral Hypoperfusion
  2. 142
    “…Apoptosis was assessed by TUNEL assay and correlated with the adipocytes histological morphometric analysis. …”
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    Defective Apoptosis in Intestinal and Mesenteric Adipose Tissue of Crohn’s Disease Patients
  3. 143
    “…TUNEL-positive nuclei were also detected in nucellus and nucellar projection as well as in embryo surrounding region during early caryopsis development. …”
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    Caspase-Like Activities Accompany Programmed Cell Death Events in Developing Barley Grains
  4. 144
    “…TUNEL-positive spermatogenic cells in 75 days old offspring was significantly increased in the atrazine group compared with the saline group (p≤0.001). …”
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    The effect of crocin on testicular tissue and sperm parameters of mice offspring from mothers exposed to atrazine during pregnancy and lactation periods: An experimental study
  5. 145
    “…DNA fragmentation, an apoptosis process, can be examined using TUNEL assay. A few TUNEL-positive hepatocytes, compared to the exercise only group, were observed in the livers from exhaustive animals supplemented with GT. …”
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    Ganoderma tsugae Hepatoprotection against Exhaustive Exercise-Induced Liver Injury in Rats
  6. 146
    “…RESULTS: No significant difference was observed between non-vitrified and vitrified groups in normality rate of follicles, the levels of hormones, TUNEL positive cells and caspase-3/7 activity. But in all LIF-treated groups, the levels of 17-β estradiol and progesterone were higher and TUNEL signals and caspase-3/7 activity were lower than non-LIF treated groups. …”
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    Analysis of Apoptosis in Cultured Human Vitrified Ovarian Tissue in the Presence of Leukemia Inhibitory Factor
  7. 147
    “…We demonstrated that, as compared with non-transgenic (nTg) mice, the accumulation of α-synuclein in the SNR of aged Pitx3-A53Tα-Syn × Tau(–/–) mice was increased obviously, which was accompanied by the considerable degeneration of PV(+) neurons and the massive generation of apoptotic NeuN(+)TUNEL(+) co-staining neurons. Interestingly, PV was not costained with TUNEL, a marker of apoptosis. …”
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    Tau Knockout and α-Synuclein A53T Synergy Modulated Parvalbumin-Positive Neurons Degeneration Staging in Substantia Nigra Pars Reticulata of Parkinson’s Disease-Liked Model
  8. 148
    por Alcigir, Mehmet Eray, Ozkan, Ozcan
    Publicado 2022
    “…CONCLUSION: There were an increased mTOR expression and stabilized caspases and TUNEL expression in these subgroups, the RIPK3 expressions were found to be low when compared with all of the antivenom administration groups. …”
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    The Evaluation of Androctonus crassicauda Antivenom against the Effects of Aegaeobuthus nigrocinctus Scorpion Venom on Autophagy, Apoptosis and Necroptosis
  9. 149
    “…Apoptotic cells were identified morphologically and by a DNA fragmentation labelling technique (TUNEL). Although the tumour cell density of Bcl-2, p53, Bax, PCNA and TUNEL positivity correlated with patient survival, a spatially organized expression pattern was further recognized in stroma-poor differentiating tumours. …”
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    Spatial association of apoptosis-related gene expression and cellular death in clinical neuroblastoma.
  10. 150
    “…Both Bcl-2 and apoptosis (TUNEL) were generally expressed at a modest level. …”
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    Fas receptor is expressed in human lung squamous cell carcinomas, whereas bcl-2 and apoptosis are not pronounced: a preliminary report.
  11. 151
    “…Analysis of cell cycle and DNA fragmentation (TUNEL) showed that both nC(60) and C(60)(OH)(24) caused G1 arrest of HUVECs and C(60)(OH)(24) induced significant apoptosis (21 ± 2% TUNEL(+) cells at 100 μg/mL of C(60)(OH)(24) vs. 4 ± 2% TUNEL(+) cells in control; p < 0.001). …”
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    Adverse effects of fullerenes on endothelial cells: Fullerenol C(60)(OH)(24) induced tissue factor and ICAM-1 membrane expression and apoptosis in vitro
  12. 152
    “…By contrast, TUNEL positive nuclei in TM cells were observed in the examined adult donor specimens. …”
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    Human anterior chamber angle development without cell death or macrophage involvement
  13. 153
    “…The thickness of outer nuclear layers of control retinas decreased with time, while the thickness of siRNA transfected retinas was significantly preserved compared to control at P16 (p=0.0021). In TUNEL assays, siRNA for ASK-1 significantly decreased TUNEL-positive cells (49% and 42% of controls at P13 and 16, p=0.039 and 0.0028, respectively). …”
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    RNA interference for apoptosis signal-regulating kinase-1 (ASK-1) rescues photoreceptor death in the rd1 mouse
  14. 154
    “…RESULTS: The periphery of the lenticule had greater TUNEL-positive cells compared to the center of the lenticule in both fresh and cryopreserved groups. …”
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    Cornea lenticule viability and structural integrity after refractive lenticule extraction (ReLEx) and cryopreservation
  15. 155
    “…Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay, 4′,6-Diamidino-2-phenylindole (DAPI) TUNEL assay, DAPI staining, and caspase-3 activity assay verified that the tumor cells had undergone apoptosis induced by apoptin. …”
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    Nonviral gene therapy in vivo with PAM-RG4/apoptin as a potential brain tumor therapeutic
  16. 156
    “…Double-staining with TUNEL and an antibody recognizing epidermal marker showed that embryonic epithelium is the main target of Spiroplasma-induced male-specific apoptosis. …”
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    Male-Killing Spiroplasma Induces Sex-Specific Cell Death via Host Apoptotic Pathway
  17. 157
    “…Immunocytochemical and TUNEL assays revealed increased numbers of TUNEL-positive cells that express nestin, suggesting that the drop in numbers of neuroblasts was due to a combination of impaired proliferation and apoptosis of progenitor cells. …”
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    Congenitally Acquired Persistent Lymphocytic Choriomeningitis Viral Infection Reduces Neuronal Progenitor Pools in the Adult Hippocampus and Subventricular Zone
  18. 158
    “…Finally, the brains of rat offspring were removed to use for nano-silver level measurement and TUNEL staining. The mean of TUNEL positive cell numbers per unit area (NA) in different regions of hippocampus were compared in all animal groups. …”
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    The effects of nano-silver and garlic administration during pregnancy on neuron apoptosis in rat offspring hippocampus
  19. 159
    “…Terminal deoxynucleotidyl transferase-mediated dUTP nick end-labelling (TUNEL) indicated a sharp rise in apoptosis during ageing. …”
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    Apoptosis in capillary endothelial cells in ageing skeletal muscle
  20. 160
    “…Leptin target cells in SVZ neurospheres were identified by double TUNEL/phenotypic marker immunocytofluorescence as differentiating neurons mostly. …”
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    Leptin-dependent neurotoxicity via induction of apoptosis in adult rat neurogenic cells
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