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  1. 2121
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    Air pollution and the incidence of ischaemic and haemorrhagic stroke in the South London Stroke Register: a case–cross-over analysis
  2. 2122
    “…RESULTS: Loneliness was distributed in a slight U-shaped form from 15 to 75+ year olds, with 64.1% of participants who had never felt lonely. …”
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    Loneliness is adversely associated with physical and mental health and lifestyle factors: Results from a Swiss national survey
  3. 2123
    “…Multivariate logistic-regression analyses (adjusted for confounding variables) showed that a 1 U/L increase in DPP4a was associated with a decreased incidence of left ventricular systolic dysfunction (LVSD) (adjusted odds ratio: 0.90; 95% CI: 0.87–0.94; p < 0.01). …”
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    Plasma dipeptidyl-peptidase-4 activity is associated with left ventricular systolic function in patients with ST-segment elevation myocardial infarction
  4. 2124
    “…METHODS: (1) We used survival analysis to quantify temporal differences in waitlist qualification by applying 3 kidney-function-estimating equations (Cockcroft-Gault, Modification of Diet in Renal Disease study, Chronic Kidney Disease Epidemiology Collaboration) to serial creatinine measurements from 3 patient cohorts: 1 of waitlisted patients at a major U.S. academic center and 2 national, multicenter cohorts of chronic kidney disease patients (African American Study of Kidney Disease and Hypertension, Modification of Diet in Renal Disease). (2) Survival analysis assessed whether requiring patients to demonstrate persistently reduced renal function on 2 occasions at least 90 days apart would meaningfully change qualification order. …”
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    Refining the Policy for Timing of Kidney Transplant Waitlist Qualification
  5. 2125
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    A multi-gene phylogeny of Lactifluus (Basidiomycota, Russulales) translated into a new infrageneric classification of the genus
  6. 2126
    “…Common virulence factors, including ACF, IlpA, OmpU, Flagellin, Cya, Hemolysin and MARTX, were detected in the genome, which are likely responsible for the virulence of QT520. …”
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    Complete genome sequence and comparative genomics of the golden pompano (Trachinotus ovatus) pathogen, Vibrio harveyi strain QT520
  7. 2127
    “…Hair from 86% of individuals and 77% of children exceeded a USEPA (U.S. Environmental Protection Agency) provisional level (1.2 µg/g) that could result in child developmental impairment. …”
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    Spatial, Temporal, and Dietary Variables Associated with Elevated Mercury Exposure in Peruvian Riverine Communities Upstream and Downstream of Artisanal and Small-Scale Gold Mining
  8. 2128
    “…A high-resolution description of the DNA-binding specificity for 131 Ciona robusta (formerly C. intestinalis type A) transcription factors by SELEX-seq is provided and used to map candidate binding sites across the Ciona robusta and Phallusia mammillata genomes. Finally, use of a WashU Epigenome browser enhances genome navigation, while a Genomicus server was set up to explore microsynteny relationships within tunicates and with vertebrates, Amphioxus, echinoderms and hemichordates.…”
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    ANISEED 2017: extending the integrated ascidian database to the exploration and evolutionary comparison of genome-scale datasets
  9. 2129
    “…E3 ubiquitin (UB) ligases E4B and carboxyl terminus of Hsc70-interacting protein (CHIP) use a common U-box motif to transfer UB from E1 and E2 enzymes to their substrate proteins and regulate diverse cellular processes. …”
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    Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer
  10. 2130
    “…Disruption of zupT but not znuA in U112 impaired growth under zinc limitation, suggesting that ZupT is the primary mechanism of zinc acquisition under these conditions. …”
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    Zinc Acquisition Mechanisms Differ between Environmental and Virulent Francisella Species
  11. 2131
    “…Furthermore, luciferase reporter assay data indicated that beclin 1 was a direct target of miR-30a in U251 cells. In summary, this study demonstrated that miR-30a increases the chemosensitivity of glioblastoma U251 cells to temozolomide by directly targeting beclin 1 and inhibiting autophagy. …”
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    MicroRNA-30a increases the chemosensitivity of U251 glioblastoma cells to temozolomide by directly targeting beclin 1 and inhibiting autophagy
  12. 2132
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    Ammonia Emission and Deposition in Scotland and Its Potential Environmental Impacts
  13. 2133
    “…They did not demonstrate much cognitive impairment in the Morris water maze or a water U-maze, but had slower processing reaction times in those tests and in a two-way active avoidance task. …”
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    Loss of glutamate signaling from the thalamus to dorsal striatum impairs motor function and slows the execution of learned behaviors
  14. 2134
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    Gravity of human impacts mediates coral reef conservation gains
  15. 2135
    “…METHODS: Human PASMCs were cultured under hypoxic conditions. miR-17-5p expression was determined by real-time RT-PCR. A BrdU incorporation assay and time-lapse recording were utilized to determine cell proliferation and migration. …”
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    Upregulation of microRNA-17-5p contributes to hypoxia-induced proliferation in human pulmonary artery smooth muscle cells through modulation of p21 and PTEN
  16. 2136
    “…The spliced transcripts encode a regulatory uORF upstream of Kaposin A with alterations in intervening repeat sequences yielding novel or deleted Kaposin B/C-like sequences. …”
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    Quantitative RNAseq analysis of Ugandan KS tumors reveals KSHV gene expression dominated by transcription from the LTd downstream latency promoter
  17. 2137
    “…With respect to YSZ ceramic coating (500 μm), a higher U(50) value of 88 kV is obtained. This is mainly due to that YSZ has a lower permittivity, which can generate a more uniform electric field distribution between the rod and plane electrodes, bringing about a higher breakdown voltage.…”
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    Improvement of dielectric performance of solid/gas composite insulation with YSZ/ZTA coatings
  18. 2138
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    Clusterin silencing restores myoblasts viability and down modulates the inflammatory process in osteoporotic disease
  19. 2139
    “…We found that overexpression of active, but not the kinase inactive DYRK1A in U-2 OS cells inhibits accumulation of 53BP1 at the DSB sites in the RNF169-dependent manner. …”
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    DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169
  20. 2140
    “…We present an assessment methodology to evaluate the sustainability of agricultural systems as applied to a southeastern U.S. river basin. We utilized detailed, crop-level cultivation information to calculate sustainability indicators (relative to well-water irrigation) at the basin scale (6-digit Hydrologic Unit Codes). 40 design configurations comprising crop types and irrigation practices were evaluated to demonstrate the methodology’s robustness. …”
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    Sustainability assessment of agricultural rainwater harvesting: Evaluation of alternative crop types and irrigation practices
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