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  1. 2501
    “…RESULTS: Here we characterize that FIONA1 is an Arabidopsis U6 m(6)A methyltransferase that installs m(6)A in U6 snRNA and a small subset of poly(A)(+) RNA. …”
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    FIONA1 is an RNA N(6)-methyladenosine methyltransferase affecting Arabidopsis photomorphogenesis and flowering
  2. 2502
    “…PRINCIPAL CONCLUSIONS: We demonstrated excellent real-world effectiveness of mRNA vaccines in preventing ED presentation for SARS-COV-2 in a diverse U.S. cohort. Notably, vaccine effectiveness improved with increasing BMI (until class 2 obesity).…”
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    Real world SARS-COV-2 vaccine effectiveness in a Miami academic institution
  3. 2503
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    The 1(st) year of the COVID-19 epidemic in Estonia: a population-based nationwide sequential/consecutive cross-sectional study
  4. 2504
    “…RESULTS: The total of 49 JIA patients were analyzed, of whom 18 JIA-U, compared with a JIA-U past cohort of 66 patients. Systemic corticosteroids were used significantly less in the current JIA-U group (p = 0.008) than in the past one. …”
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    Juvenile idiopathic arthritis-associated uveitis in the era of biological therapy: how the disease changed in more than 20 years of observation in a tertiary referral center in Rome (Italy)
  5. 2505
    “…Therefore, we investigated the number of days required to yield a better association between the morning uNa/K ratio and home BP (HBP) and determined a morning uNa/K ratio value that can be used as a reference value in participants who are not taking antihypertensive medication. …”
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    Consideration of the reference value and number of measurements of the urinary sodium-to-potassium ratio based on the prevalence of untreated home hypertension: TMM Cohort Study
  6. 2506
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    One year of surgical mask testing at the University of Bologna labs: Lessons learned from data analysis
  7. 2507
    “…When analyzing the relationship between MHR and NAFLD risk, a reverse U-shaped curve with an inflection point of 0.36 for MHR was found in women. …”
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    Association Between Monocyte to High-Density Lipoprotein Cholesterol Ratio and Risk of Non-alcoholic Fatty Liver Disease: A Cross-Sectional Study
  8. 2508
    “…The nuclei within the tumor regions were segmented on the histology images of biopsy samples using a weighted U-Net model. Five pathomic feature subsets were extracted from segmented digitized samples, including the morphological, intensity-based, texture, graph-based and wavelet features. …”
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    Quantitative digital histopathology and machine learning to predict pathological complete response to chemotherapy in breast cancer patients using pre-treatment tumor biopsies
  9. 2509
    “…In postmenopausal women, menopause-related microbiome alterations were associated with adverse cardiometabolic profiles. In summary, in a large U.S. Hispanic/Latino population, menopause is associated with a gut microbiome more similar to that of men, perhaps related to the common condition of a low estrogen/progesterone state. …”
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    Menopause Is Associated with an Altered Gut Microbiome and Estrobolome, with Implications for Adverse Cardiometabolic Risk in the Hispanic Community Health Study/Study of Latinos
  10. 2510
    “…Mutations were introduced into an archaeal promoter BRE (transcription factor B [TFB] recognition element), a terminator U-tract region, and a gene coding region. …”
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    CRISPR-Cas9 Toolkit for Genome Editing in an Autotrophic CO(2)-Fixing Methanogenic Archaeon
  11. 2511
    “…Silencing Notch1 signaling using a doxycycline-inducible Notch1 RNA-interfering system or treatment with chetomin, a HIF pathway inhibitor, retarded tumor development with a significant anti-cancer effect in a murine U251-xenograft model. Using GBM patient tissue microarray analysis, a significant increase in HIF-1α expression was identified in the group with Notch1 expression compared to the group without Notch1 expression among those with positive HIF-1α expression. …”
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    Atypical induction of HIF-1α expression by pericellular Notch1 signaling suffices for the malignancy of glioblastoma multiforme cells
  12. 2512
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    Gender and Power Dynamics of Social Relationships Shape Willingness to Participate in Biomedical HIV Prevention Research Among South African Adolescents and Young Adults
  13. 2513
    “…On the other hand we developed DeepMeta, a multiclass U-Net 3+ deep learning model to automatically segment the images. …”
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    Deep learning model for automatic segmentation of lungs and pulmonary metastasis in small animal MR images
  14. 2514
    “…To address this gap, we conducted an evaluation of a local CCP program at a large U.S. academic medical center, the University of North Carolina Medical Center (UNCMC), and patterned our evaluation around the dimensions of the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework to systematically describe key implementation-relevant metrics. …”
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    Evaluation of a COVID-19 convalescent plasma program at a U.S. academic medical center
  15. 2515
    “…FUNDING: NIH/National Cancer Institute grants (K08CA218690, P01 CA117969, R50 CA243707-01A1, U54CA224065), the Skip Viragh Foundation, the Bettie Willerson Driver Cancer Research Fund, and a Cancer Center Support Grant for the Flow Cytometry and Cellular Imaging Core Facility (P30CA16672).…”
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    3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma
  16. 2516
    “…METHODS: Children with cerebral palsy and spasticity in ≥ 1 upper limb received up to 4 injection cycles of abobotulinumtoxinA (2 U/kg (cycle 1 only), 8U/kg and 16U/kg) into the elbow and wrist flexors and other upper limb muscles selected to support individual treatment goals. …”
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    GOAL ATTAINMENT AFTER TREATMENT WITH ABOBOTULINUMTOXINA AND A TAILORED HOME THERAPY PROGRAMME IN CHILDREN WITH UPPER LIMB SPASTICITY: DESCRIPTIVE, EXPLORATORY ANALYSIS OF A LARGE RANDOMIZED, CONTROLLED STUDY
  17. 2517
    por Ryu, Chan Ju
    Publicado 2022
    “…METHODS: PET data were first normalized by volume and divided into five amyloid accumulation zones through axial, coronary, and thalamic slices. A single U-Net was trained using a divided dataset for one of these zones. …”
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    Automatic lesion detection and segmentation in (18)F-flutemetamol positron emission tomography images using deep learning
  18. 2518
    “…METHODS: We examined hospital encounters for acute coronary syndrome, arrhythmia disorders, heart failure (HF), and valvular heart disease from a large U.S., multisite, integrated academic health system among patients with established cardiovascular care within the system. …”
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    Investigating the Association Between Telemedicine Use and Timely Follow-Up Care After Acute Cardiovascular Hospital Encounters
  19. 2519
    “…High scores for PDI, hPDI, and aPDI were all related to a reduced risk of low HDL-C (OR: 0.638, 95% CI: 0.491–0.823; OR: 0.661, 95% CI: 0.502–0.870; OR: 0.580, 95% CI: 0.443–0.758). Conversely, a high uPDI score was associated with an increased risk of low HDL-C (OR: 1.349, 95% CI: 1.046–1.740). …”
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    Association between Different Types of Plant-Based Diets and Dyslipidemia in Middle-Aged and Elderly Chinese Participants
  20. 2520
    por Chang, Perng-Kuang
    Publicado 2023
    “…Expression of single guide RNA (sgRNA) cassettes was controlled by the A. flavus U6 promoter and terminator. The high transformation and gene-targeting frequencies of this system made generation of A. flavus gene knockouts with or without phenotypic changes effortless. …”
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    A Simple CRISPR/Cas9 System for Efficiently Targeting Genes of Aspergillus Section Flavi Species, Aspergillus nidulans, Aspergillus fumigatus, Aspergillus terreus, and Aspergillus niger
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