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Mostrando 1,161 - 1,180 Resultados de 3,321 Para Buscar '"t.A.T.u."', tiempo de consulta: 1.08s Limitar resultados
  1. 1161
    “…Here in this study, the clustered regularly interspaced short palindromic repeat (CRISPR) system was employed to establish a genome editing system in A. mediterranei U32. Specifically, the Francisella tularensis subsp. novicida Cas12a (FnCas12a) gene was first integrated into the U32 genome to generate target-specific double-stranded DNA (dsDNA) breaks (DSBs) under the guidance of CRISPR RNAs (crRNAs). …”
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    CRISPR-Cas12a-Assisted Genome Editing in Amycolatopsis mediterranei
  2. 1162
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    Medical students’ knowledge and attitudes regarding vaccination against measles, influenza and HPV. An international multicenter study
  3. 1163
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    Dynamic allosteric communication pathway directing differential activation of the glucocorticoid receptor
  4. 1164
    “…This paper describes the application of Intervention Mapping (IM) in the development of Proyecto Mariposa, a comprehensive SCP program targeting Latina breast cancer survivors living in a rural U.S.–Mexico border region. We conducted a needs assessment using focus groups (n = 40) and individual interviews (n = 4) with stakeholders to elicit their needs and preferences relating to SCPs and SCP aid (Step1). …”
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    Development of a Survivorship Care Plan (SCP) Program for Rural Latina Breast Cancer Patients: Proyecto Mariposa—Application of Intervention Mapping
  5. 1165
    “…The reaction of oximoinoketone intermediate with ten different aromatic aldehyde and ammonium acetate in refluxing acetic acid condition give imidazole derived product, the IL-1β inhibitory assay were performed on Human PBMCs (peripheral blood mononuclear cells) using an enzyme-linked immunosorbent assay (ELISA) kit and then in computational part the binding mode of the best compound was accomplished by docking in Crystal structure of p38 MAP kinase (PDB ID: 1A9U) compared with SB202190 as standard drug. All compounds were synthesized and evaluated in biological assay showing the inhibitory activity from 28% to 82% compared to SB202190 and binding mode analysis revealed that the hydrogen-bond interactions with residues (Met109, Val30) were key point in inhibitor binding. …”
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    Design and Synthesis of Novel 1-hydroxy-2,4,5-triaryl Imidazole Derivatives as Anti-cytokine Agents
  6. 1166
    “…Here, we aimed to uncover genome-wide alterations in uracil pattern upon drug treatments in human cancer cell line models derived from HCT116. We developed a straightforward U-DNA sequencing method (U-DNA-Seq) that was combined with in situ super-resolution imaging. …”
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    Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments
  7. 1167
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    In vivo efficacy of carvacrol on Campylobacter jejuni prevalence in broiler chickens during an entire fattening period
  8. 1168
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    Correction to: Vilnius Declaration on chronic respiratory diseases: multisectoral care pathways embedding guided self-management, mHealth and air pollution in chronic respiratory diseases
  9. 1169
    “…As the biosubstrates, we tested natural double-stranded DNA, synthetic RNA polynucleotides (single-poly(A), double-poly(A)poly(U) and triple-stranded poly(A)2poly(U)), DNA G-quadruplex structures (G4s), and bovine serum albumin (BSA) protein. …”
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    On the Different Mode of Action of Au(I)/Ag(I)-NHC Bis-Anthracenyl Complexes Towards Selected Target Biomolecules
  10. 1170
    “…METHODS: We enrolled ten patients with SARS-CoV-2 infection who attended the Infectious Diseases Unit of the A.O.U. Federico II of Naples, from March 2020 to April 2020. …”
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    No Detection of SARS-CoV-2 RNA on Urethral Swab in Patients with Positive Nasopharyngeal Swab
  11. 1171
    “…In addition, we figured out 28 optimal codons and most of them ended with A or U. The project here can offer important information for further studies on enhancing the gene expression using codon optimization in heterogeneous expression system, predicting the genetic and evolutionary mechanisms in R. palmatum.…”
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    Analysis of synonymous codon usage of transcriptome database in Rheum palmatum
  12. 1172
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    Successful implementation of classical ketogenic dietary therapy in a patient with Niemann-Pick disease type C
  13. 1173
    “…In addition, associations between climate and dengue are presented as a reversed slide-shaped curve for dengue-humidity and a reversed U-shaped curves for dengue-temperature and dengue-precipitation. …”
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    Climate-based dengue model in Semarang, Indonesia: Predictions and descriptive analysis
  14. 1174
    “…Changes in cell viability and proliferation were evaluated using an MTT assay and a BrdU assay. The cytoskeleton structure organization (zyxin and F-actin) was visualized by confocal laser scanning microscopy. …”
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    Biological Response Induced in Primary Human Gingival Fibroblasts upon Exposure to Various Types of Injectable Astringent Retraction Agents
  15. 1175
    Publicado 2021
    “…We show that by training a vanilla U-Net on semi-synthetic data only and applying a simple post-processing, we are able to match the results of the same network trained on a publicly available manually labeled real dataset.…”
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    Image Compositing for Segmentation of Surgical Tools Without Manual Annotations
  16. 1176
    “…The Dice coefficient of the expanded U-Net is 7.6 larger than that of a general U-Net, and the IOU coefficient of the expanded U-Net is 11 larger than that of the general U-Net. …”
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    Segmentation and recognition of breast ultrasound images based on an expanded U-Net
  17. 1177
    “…The system, designed with a cascade network structure, was developed using deep-learning technology for automatic tumor detection, visual assessment, and grading prediction. Specifically, a modified U-Net convolutional neural network was first established to segment tumor images. …”
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    Automatic Meningioma Segmentation and Grading Prediction: A Hybrid Deep-Learning Method
  18. 1178
    “…The median U-IXP concentration on admission was 0.58 μmol/g creatinine (Cre; IQR 0.35–0.95 μmol/g Cre). A higher U-IXP concentration was an independent predictor of the primary outcome adjusted for clinical potential confounders and was associated with a significantly higher cumulative incidence of the primary outcome (71% vs. 16%, P=0.001) at a cut-off of 0.93 μmol/g Cre. …”
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    Urinary Isoxanthopterin in Heart Failure Patients
  19. 1179
    “…We thus propose a pipelined approach where each stage is intended to deal with or to leverage a peculiar characteristic of breast DCE-MRI data: the use of a breast-masking pre-processing to remove non-breast tissues; the use of Three-Time-Points (3TP) slices to effectively highlight contrast agent time course; the application of a motion-correction technique to deal with patient involuntary movements; the leverage of a modified U-Net architecture tailored on the problem; and the introduction of a new “Eras/Epochs” training strategy to handle the unbalanced dataset while performing a strong data augmentation. …”
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    A Pipelined Tracer-Aware Approach for Lesion Segmentation in Breast DCE-MRI
  20. 1180
    “…Human CSTF2 binds to a downstream U- or G/U-rich sequence through its RNA recognition motif (RRM) regulating C/P. …”
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    Electrostatic Interactions between CSTF2 and pre-mRNA Drive Cleavage and Polyadenylation
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