“…Here we conducted an in-depth metagenomic analysis of the taxonomic and metabolic capabilities of a catfish pond sediment microbiome from a southeastern U.S. aquaculture farm in Mississippi using Illumina next-generation sequencing. …”
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“…In this study, cardiac fibroblasts (CFb) was isolated by the trypsin digestion method; a BrdU proliferation assay was adopted to determine cell proliferation; an immunofluorescence assay was used to measure intracellular reactive oxygen species (ROS); immunocytochemistry staining and Western blotting assay were used to detect phosphorylated p38 mitogen activated protein kinase (p-p38MAPK) and transforming growth factor-β(1) (TGF-β(1)) protein expression, respectively. …”
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“…Pooling the data of Estonian and Latvian SPs yielded a mean U(SG) value of 1.021 ± 0.007. Hypohydration (defined as a U(SG) ≥ 1.020) was evident altogether in fifty SPs (61.7%) and one of them had a U(SG) value greater than 1.030. …”
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“…D., Tamburrino, G., Hoskisson, P. A., Zachariae, U., Javelle, A. The lipid environment determines the activity of the Escherichia coli ammonium transporter AmtB.…”
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“…Objective To explore the medication-related experiences of patients and their families when a child or young person is prescribed regular medication. Setting A specialist U.K. paediatric hospital. Method Semi-structured face-to-face interviews of 24 parents/carers, children or young people, who had been taking two or more medications for 6 weeks or longer. …”
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“…Motif analysis of the top 50 sequences provided a highly conserved sequence: 5′-A[A/C][C/G][G/U][U/A]ACAGAGGG[U/A]GG[A/C] GAGUGGGU-3′. APT1, APT2, and APT5 embracing this motif generated secondary structures with similar topological characteristics. …”
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“…For all‐cause mortality, all methods identify a steep U‐shape. The metacurve and mvmeta methods perform well in combining complex exposure‐disease relationships across studies.…”
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“…Methods  Semistructured interviews from a cross-section of neonatal physicians ( n  = 14) and nurses ( n  = 8) from a single U.S. medical center were collected 18 months following the conclusion of the predictive monitoring technology randomized control trial. …”
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“…After adjusting for potential confounders, compared with the deficient group, the ORs (95%CI) of CVDs were 0.68 (0.50, 0.91) in the insufficient group and 0.81 (0.56, 1.16) in the sufficient group. A nonlinear (U-shaped) association was observed between the risk of CVD and 25(OH)D concentration. …”
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“…BACKGROUND: Observational studies have suggested that selenium (Se) may have beneficial effects against certain cardiovascular outcomes, with a possible U‐shaped association. We assessed the hypothesis that blood Se concentration might be inversely associated with the prevalence of stroke and the relationship would be nonlinear. …”
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“…Using reverse genetics and comparative genomics, we identify two factors responsible for 5-hydroxyuridine (ho(5)U) formation, which is the first step of the cmo(5)U synthesis: TrhP (formerly known as YegQ), a peptidase U32 family protein, is involved in prephenate-dependent ho(5)U formation; and TrhO (formerly known as YceA), a rhodanese family protein, catalyzes oxygen-dependent ho(5)U formation and bypasses cmo(5)U biogenesis in a subset of tRNAs under aerobic conditions. …”
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“…We further demonstrate that Ψ strengthens U4/U6 RNA–RNA and U2B"/U2A’ proteins-U2 snRNA interaction at elevated temperatures. …”
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“…These results indicate that AAV-mediated delivery of a modified U1snRNP particle may be a novel therapeutic option against SMA.…”
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“…Combining sympathetic and parasympathetic responses to evaluate overall sympathovagal balance, there was a significant U-shaped relationship with reaction time. …”
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“…We evaluated one hundred twenty three control strategies comprising various combinations of testing, culling, and hygiene, and found that the association of paratuberculosis with mastitis alters the ranking of specific MAP control programs, but only slightly alters the cost-benefit difference of particular MAP control components, as measured by the distribution of net present value of a representative U.S. dairy operation. In particular, although testing and culling for MAP resulted in a reduction in MAP incidence, that control led to lower net present value (NPV) per cow. …”
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“…Any effect at the codon immediately proximal to the primary stop can be accounted for by a preference for a T/U residue immediately following the stop, although if anything, TT- and TC- starting codons are preferred. …”
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“…Mass analysis indicated HOCl caused successive mass increases of 16 a.m.u., consistent serial addition of molecular oxygen to the protein. …”
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