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  1. 1781
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    Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma
  2. 1782
    “…CONCLUSION: We report novel, longitudinal data for AGD during infancy in a large U.K. birth cohort. AGD was sex dimorphic at all ages studied. …”
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    Anogenital Distance from Birth to 2 Years: a Population Study
  3. 1783
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    8-Hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer
  4. 1784
    “…This study investigated cell cycle regulation and the roles of C/EBPβ, C/EBPα and PPARγ during adipocyte differentiation from hBMSCs. RESULTS: Utilising a BrdU incorporation assay and manual cell counting it was demonstrated that induction of adipocyte differentiation in culture resulted in 3T3-L1 pre-adipocytes but not hBMSCs undergoing mitotic clonal expansion. …”
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    Characterization of adipocyte differentiation from human mesenchymal stem cells in bone marrow
  5. 1785
    “…OBJECTIVES: We hypothesize an association between rainfall and pediatric emergency department (ED) visits for AGI that may represent an unrecognized, endemic burden of pediatric disease in a major U.S. metropolitan area served by municipal drinking water systems. …”
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    Association between Rainfall and Pediatric Emergency Department Visits for Acute Gastrointestinal Illness
  6. 1786
    “…Delivery of galectin-3C intravenously via an osmotic pump in a subcutaneous U266 cell NOD/SCID mouse model of MM significantly inhibited tumor growth. …”
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    Galectin-3C Inhibits Tumor Growth and Increases the Anticancer Activity of Bortezomib in a Murine Model of Human Multiple Myeloma
  7. 1787
    “…Mean daily relative humidity (RH) also had a significant U-shaped association with daily emergency health-related calls with call frequency beginning to increase with RH greater than 70–74% (10–25% of the RH distribution). …”
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    Help-Seeking Behavior during Elevated Temperature in Chinese Population
  8. 1788
    “…METHODS: We hybridized total RNA isolated from renal cell tumors and adjacent normal tissue to Affymetrix U133A and U133B arrays. We removed samples with technical defects and removed probesets that failed to exhibit sequence-specific hybridization in any of the samples. …”
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    Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data
  9. 1789
    por Kim, Jong Yeon
    Publicado 2012
    “…In multivariate analysis, using OIUs as a reference, U- or J-shaped associations were observed for five health risk behavior indices (current smoking, current drinking, drug abuse, sexual intercourse, sedentary behavior on weekdays) and four mental health indices (stressed, depressed, suicidal ideation, attempted suicide) in both genders. …”
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    The Nonlinear Association Between Internet Using Time for Non-Educational Purposes and Adolescent Health
  10. 1790
    “…Furthermore, induction of IFN-β by a smaller, U/A-rich region within the 3′ UTR was completely 5′PPP-independent. …”
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    The 3′ Untranslated Regions of Influenza Genomic Sequences Are 5′PPP-Independent Ligands for RIG-I
  11. 1791
    por Haegeman, Bart, Weitz, Joshua S
    Publicado 2012
    “…This model predicts that gene frequency distributions possess a characteristic U-shape even in the absence of selective forces driving genome and population structure. …”
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    A neutral theory of genome evolution and the frequency distribution of genes
  12. 1792
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    Effect of Age and Vaccination With a Pneumococcal Conjugate Vaccine on the Density of Pneumococcal Nasopharyngeal Carriage
  13. 1793
    “…Rapamycin (Rapa) and CRM197, inhibitors of mTor and HB-EGF respectively, could inhibit the expression of type I collagen in the cultured primary cardiac fibroblasts and Rapa suppressed interstitial fibrosis of the heart tissues in vivo. In addition, a BrdU assay showed that HB-EGF increased proliferation of cardiac fibroblasts by 30% compared with cells without HB-EGF treatment. …”
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    Heparin-Binding EGF-Like Growth Factor Induces Heart Interstitial Fibrosis via an Akt/mTor/p70s6k Pathway
  14. 1794
    “…DESIGN: Dynamic compartmental model of HIV and HCV in a population of IDUs and non-IDUs for a representative U.S. urban center with 2.5 million adults (age 15–59). …”
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    Cost Effectiveness of Screening Strategies for Early Identification of HIV and HCV Infection in Injection Drug Users
  15. 1795
    por Shi, Bing, Gao, Wei, Wang, Juan
    Publicado 2012
    “…At the 5′ end, conserved miRNAs have a preference for base U, while less-conserved miRNAs have a preference for a non-U base in mammals. This difference does not exist in insects and plants, in which both conserved miRNAs and less-conserved miRNAs have a preference for base U at the 5′ end. …”
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    Sequence Fingerprints of MicroRNA Conservation
  16. 1796
    “…Adipocyte formation by ESCs is inhibited by amiloride treatment, a specific uPA inhibitor. Likewise, ESCs expressing ectopic PAI-1 under the control of an inducible expression system display reduced adipogenic capacities after induction of the gene. …”
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    The Plasminogen Activation System Modulates Differently Adipogenesis and Myogenesis of Embryonic Stem Cells
  17. 1797
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    Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours
  18. 1798
    “…METHODS: This pilot study includes five patients, aged 60 to 75, with a history of claudication and recruited from September 2010 to February 2011 at the A.O.U. Federico II of Naples. PBMNCs have been implanted three times in the limb with the worst ABI value in all the patients included in the study. …”
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    Peripheral blood mono-nuclear cells implantation in patients with peripheral arterial disease: a pilot study for clinical and biochemical outcome of neoangiogenesis
  19. 1799
    “…OBJECTIVE: We estimated the prevalence and incidence of diabetes among specific subgroups of Asians and Pacific Islanders (APIs) in a multiethnic U.S. population with uniform access to care. …”
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    Elevated Rates of Diabetes in Pacific Islanders and Asian Subgroups: The Diabetes Study of Northern California (DISTANCE)
  20. 1800
    “…We estimate the economic impact of community-acquired pneumonia (CAP) for adults with asthma, diabetes, chronic obstructive pulmonary disease (COPD) and congestive heart failure (CHF) in a large U.S. commercially-insured working age population. …”
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    Comorbidities as a driver of the excess costs of community-acquired pneumonia in U.S. commercially-insured working age adults
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