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  1. 2861
    “…However, the clinical performances of adopted drugs, materials, and powerful cells in the laboratory are inescapably limited by the currently available technologies. To tackle the problems, versatile microneedles are developed as the new platform for local delivery of diverse cargos with minimal invasion. …”
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  2. 2862
    “…Results: The “active” ATLAS model from JAPET, ensuring lumbar protection, was selected because it corresponds to all the specification criteria to tackle the nurses’ unmet need. Among the 14 healthcare professionals, 86% were women; the age of the nurses was between 23 years old and 58 years old. …”
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  3. 2863
    “…Efficient targeting of TAMs presents a promising approach to tackle glioma progression. Several targeting options involve chemokine signaling axes inhibitors and antibodies, anti-angiogenic factors, immunomodulatory molecules, surface immunoglobulins blockers, receptor and transcription factor inhibitors, as well as microRNAs (miRNAs), administered either as standalone or in combination with other conventional therapies. …”
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  4. 2864
    Publicado 2023
    “…Novel strategies to overcome resistance or to tackle the tumor microenvironment are currently at the forefront of the tumor immunology and cancer immunotherapies research. …”
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  5. 2865
    por Tarannum, Tanjina, Ahmed, Shoeb
    Publicado 2023
    “…While frequent surface disinfection and antiviral coating techniques are put forth by researchers as a plan of action to tackle transmission in dire situations like the Covid-19 pandemic caused by SARS-CoV-2 virus, these procedures are often laborious, time-consuming, cost-intensive, and toxic. …”
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  6. 2866
    por Smith, Michael J., Geach, James E.
    Publicado 2023
    “…With the exponential growth of astronomical data, deep learning techniques offer an unprecedented opportunity to uncover valuable insights and tackle previously intractable problems. As we enter the anticipated fourth wave of astronomical connectionism, we argue for the adoption of GPT-like foundation models fine-tuned for astronomical applications. …”
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  7. 2867
    “…Certainly, limiting our exposure to such causative events at younger ages seems our “golden opportunity” to tackle the incidence of coronary atherosclerosis and probably the answer to longevity.…”
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  8. 2868
    por Duma, Lena, Ahel, Ivan
    Publicado 2023
    “…We also discuss the use of PARP inhibitors in cancer therapy and the ways to tackle PARPi treatment resistance.…”
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  9. 2869
    “…With respect to the issue of the slow convergence precision and the tendency to trap in the local extremum of the QUATRE algorithm, this research incorporates the QUATRE algorithm with recombination mechanism (RQUATRE) to tackle the problem of parameter estimation for the improved PV modules described above. …”
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  10. 2870
    por Zaballa, Vincent D., Hui, Elliot E.
    Publicado 2023
    “…Simulation-based inference (SBI) methods tackle complex scientific models with challenging inverse problems. …”
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  11. 2871
    “…In this review, we aim to highlight the functions of LDs in plant development and response to environmental changes. In particular, we tackle the fate and roles of LDs during the plant post-stress recovery phase.…”
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  12. 2872
    “…Creating awareness, increasing transparency of available databases, and the support of academic libraries and publishing houses along with global support will serve as effective measures to tackle predatory malpractices.…”
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  13. 2873
    por Fujiwara, Takanori, Liu, Tzu-Ping
    Publicado 2023
    “…However, the general latent spaces across all predefined groups derived from these methods sometimes do not fall into researchers’ interest regarding specific patterns within groups. To tackle this issue, we adopt an emerging analysis approach called contrastive learning. …”
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  14. 2874
    “…Worrying trends of increased cardiovascular disease (CVD) risk in children, adolescents and young people in the Modern Era have channelled research and public health strategies to tackle this growing epidemic. However, there are still controversies related to the dynamic of the impact of sex, age and puberty on this risk and on cardiovascular health outcomes later in life. …”
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  15. 2875
    “…In this paper, a method is presented to tackle the problems related to the data including obstruction, clutter and noise. …”
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  16. 2876
    “…Whether from agenesis or tooth loss, several treatment modalities are currently present to tackle this task to ensure satisfactory aesthetics. …”
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  17. 2877
    “…The review suggests approaches to tackle these issues and highlights recent advances in the field of biodegradable membranes for water purification. …”
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  18. 2878
    “…[Image: see text] The major challenges of hyaluronic acid-based bioinks in extrusion-based three-dimensional bioprinting are poor printability and low printing accuracy. To tackle the challenges, we developed a bioink in which two components are blended: gallic acid-functionalized hyaluronic acid (HAGA) and hyaluronic acid methacrylate (HAMA). …”
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  19. 2879
    “…To obtain a safe optimal controller, only one critic neural network (CNN) is utilized to tackle the complex HJI equation, leading to a decreased computational load in contrast to the utilization of the conventional actor–critic network. …”
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  20. 2880
    “…Among these methods, phage therapy has emerged as a potential solution to tackle this growing challenge. Virulent phages of the Herelleviridae family, known for their ability to cause lysis of Staphylococcus aureus, a clinically significant pathogen frequently associated with multidrug resistance, have proven to be one of the most effective viruses utilized in phage therapy. …”
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