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  1. 3001
    “…Among these, viruses are especially difficult to tackle due to the sudden transfer from animals to humans, high mutational rates, resistance to current treatments, and the intricacies of their molecular interactions with the host. …”
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    A Single-Cell Platform for Monitoring Viral Proteolytic Cleavage in Different Cellular Compartments
  2. 3002
    “…METHODS: A 1-day course was organized to tackle the main concerns of patients in respect to sexual health problems. …”
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    Educational program on sexual medicine for medical students: pilot project in Brazil
  3. 3003
    “…The scheme of predatory publishing activities is presented, and several measures are proposed to tackle the issue of predatory publishing. The awareness campaigns by professional societies, consultations with information facilitators, implementation of the criteria of best target journals, and crediting of scholars with use of integrative citation metrics, such as the h-index, are believed to make a difference.…”
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    The Pressure to Publish More and the Scope of Predatory Publishing Activities
  4. 3004
    “…A multi-dimensional strategy to tackle the global obesity epidemic requires an in-depth understanding of the mechanisms that underlie this complex condition. …”
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    Preclinical models for obesity research
  5. 3005
    por Heeney, Catherine
    Publicado 2016
    “…Drawing on actor network theory (ANT), I approach “the empirical” using the concepts of controversy and ontological uncertainty as methodological tools to tackle the problem of ethics. I suggest that these concepts also provide a bridge for understanding the ontological structure of the virtual and the actual, as described in Deleuze’s Difference and Repetition. …”
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    An “Ethical Moment” in Data Sharing
  6. 3006
    “…Noise and constant empirical motion constraints affect the extraction of distinctive spatiotemporal features from one or a few samples per gesture class. To tackle these problems, an adaptive local spatiotemporal feature (ALSTF) using fused RGB-D data is proposed. …”
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    Adaptive Local Spatiotemporal Features from RGB-D Data for One-Shot Learning Gesture Recognition
  7. 3007
    “…We urge scientific communities to make a more concerted effort to tackle this problem and propose potential approaches both for compiling non-English scientific knowledge effectively and for enhancing the multilingualization of new and existing knowledge available only in English for the users of such knowledge.…”
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    Languages Are Still a Major Barrier to Global Science
  8. 3008
    “…Although there are currently interventional pulmonary procedures available to tackle the critical airway obstruction in extreme situations, cardio-pulmonary bypass should be considered prior to the intervention to maintain the adequate gas exchange during the procedure. …”
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    Stenting of critical tracheal stenosis with adjuvant cardio-pulmonary bypass
  9. 3009
    “…Although a large number of biochemical and structural approaches have provided important information, the conformational dynamics underlying the coupling between ATP binding/hydrolysis and allocrite transport remains elusive. To tackle this issue, we performed molecular dynamic simulations for different nucleotide occupancy states of Sav1866, a prokaryotic P-glycoprotein homologue. …”
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    Unidirectional Transport Mechanism in an ATP Dependent Exporter
  10. 3010
    “…Two big challenges are (1) how to reduce the effects of technical noise; and (2) how to handle the curse of dimensionality (i.e., number of variables are way larger than the number of samples). To tackle these challenges, we propose a constrained mixture of Bayesian hierarchical models (MBHM) for detecting disease-associated genomic outcomes for data obtained from paired/matched designs. …”
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    Detecting disease-associated genomic outcomes using constrained mixture of Bayesian hierarchical models for paired data
  11. 3011
    “…This paper is one of the first attempts in the field to tackle such challenges using statistical modeling. …”
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    Quantifying Variation in Gait Features from Wearable Inertial Sensors Using Mixed Effects Models
  12. 3012
    “…Empowering students of today will enable them as tomorrow’s doctors to tackle the challenges of modern medicine…”
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    Equipping future doctors: incorporating management and leadership into medical curriculums in the United Kingdom
  13. 3013
    “…OBJECTIVES: Firefighters tackle various stressors that affect their health and job performance; therefore, assessment of their work ability is necessary. …”
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    Demographic and occupational determinants of the work ability of firemen
  14. 3014
    “…Following a global, One Health approach and based on the evaluation of the existing knowledge about these pathogens, this paper gives recommendations for prevention and infection control measures as well as proposals for various target groups to tackle the threats posed by Gram-negative bacteria and prevent the spread and emergence of new antibiotic resistances.…”
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    Antibiotic resistance: What is so special about multidrug-resistant Gram-negative bacteria?
  15. 3015
    “…Considering that the obtained structures may sustain a certain amount of static loadings, it is desirable to ensure the optimized designs to have a relatively high stiffness. To tackle this issue, we conducted a multiple objective optimization to maximize band gap size and bulk or shear modulus simultaneously with a prescribed volume fraction of solid material so that the resulting structures can be lightweight, as well. …”
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    Topological Design of Cellular Phononic Band Gap Crystals
  16. 3016
    “…Existing works often tackle this problem with additional function components. …”
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    Online Artículo Texto
    Social Welfare Control in Mobile Crowdsensing Using Zero-Determinant Strategy
  17. 3017
    “…Thus far, there have been minimal clinical successes directly targeting these genomic alterations; however research is ongoing to ultimately discover an innovative approach to tackle this devastating disease. This review will discuss the genomic variations in pancreatic cancer, and the resulting potential diagnostic and therapeutic implications.…”
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    Genomic Variations in Pancreatic Cancer and Potential Opportunities for Development of New Approaches for Diagnosis and Treatment
  18. 3018
    “…We study the problem that how to select the minimum number of sensors to guarantee the full-view coverage for the given region of interest (ROI). To tackle this issue, we derive the constraint condition of the sensor positions for full-view neighborhood coverage with the minimum number of nodes around the point. …”
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    Node Scheduling Strategies for Achieving Full-View Area Coverage in Camera Sensor Networks
  19. 3019
    “…Microfabrication offers unique tools that can tackle problems in this field, such as ease of mass production with high quality control and low cost, complexity of architecture design and a broad range of materials. …”
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    Microfabrication for Drug Delivery
  20. 3020
    “…Summary: Rational design of drug combinations has become a promising strategy to tackle the drug sensitivity and resistance problem in cancer treatment. …”
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    SynergyFinder: a web application for analyzing drug combination dose–response matrix data
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