“…The question we address in this review is whether plants, which produce a rich diversity of secondary metabolites, may provide novel antibiotics to tackle MDR microbes and novel chemosensitizers to reclaim currently used antibiotics that have been rendered ineffective by the MDR microbes. …”
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“…Developing the ideal biomaterials for wound dressing still remains challenging nowadays due to the non-biodegradable features and the lack of antimicrobial activity of conventional synthetic polymer-based dressing materials. To tackle those problems, a novel and green-based antimicrobial hydrogel dressing was synthesized in this work via modifying sugarcane bagasse cellulose with guanidine-based polymer, followed by crosslinking antimicrobial-modified cellulose with unmodified one at various ratios. …”
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“…Fundamental studies are needed to clarify these points and find new ways to tackle receptor functionality. This opinion article emphasizes the global questions attached to new descriptions of GPCRs and aims to raise our awareness of the tremendous complexity of modern receptology.…”
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“…By the later part of the century, current estimates indicate that a >50% increase in the yield of most of the important food crops including wheat, rice and barley will be needed to maintain food supplies and improve nutritional quality to tackle what has become known as ‘hidden hunger’. Improving the nutritional quality of crops has become a target for providing the micronutrients required in remote communities where dietary variation is often limited. …”
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“…Unambiguous evidence for hydrogen bond interactions between APS silanol groups and steel surface hydroxyl groups is provided for the first time in this work through deuteration of the steel substrate and allows to tackle long-lasting doubts about the most wide-spread bonding theory that has been postulated for silane adsorption on metals.…”
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“…Cancerous cells and the tumor microenvironment are among key elements involved in cancer development, progression, and resistance to treatment. In order to tackle the cells and the extracellular matrix, we herein propose the use of a class of silica-coated iron oxide nanochains, which have superior magnetic responsiveness and can act as efficient photothermal agents. …”
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“…It responds to the need for gathering and incorporating more citizen insights into future policy developments and strategic actions to tackle the global challenge of unsustainable development. …”
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“…However, reliably detecting multiple hands from cluttering scenes remains to be a challenging task because of complex appearance diversities of dexterous human hands (e.g., different hand shapes, skin colors, illuminations, orientations, and scales, etc.) in color images. To tackle this problem, an accurate hand detection method is proposed to reliably detect multiple hands from a single color image using a hybrid detection/reconstruction convolutional neural networks (CNN) framework, in which regions of hands are detected and appearances of hands are reconstructed in parallel by sharing features extracted from a region proposal layer, and the proposed model is trained in an end-to-end manner. …”
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“…The recognised risk factors for the main types of cancer are reviewed and searched through the Mexican government web pages and cancer prevention programmes to tackle the risk factors in the population. The Mexican government, a member of the World Health Organization, shows that the main approach is an early diagnosis rather than prevention, forgetting that an ounce of prevention is better than a pound of cure. …”
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“…Then, we experimentally evaluate different features and propose the most appropriate machine learning model and features for the static environment to tackle the issue of noisy components and detect earthquakes in real-time with less false alarm rates. …”
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“…This paper investigates how to leverage deep reinforcement learning to tackle whole-body mobile manipulation tasks in unstructured environments using only on-board sensors. …”
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“…Despite the ongoing efforts to tackle Buruli ulcer epidemics, the environmental reservoir of its pathogen remains elusive, underscoring the need for new approaches to improving disease prevention and management. …”
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“…However, genes that cannot be cloned in bacteria do not necessarily exert toxic effects on the final host. In order to tackle this issue, we adapted two DNA assembly workflows for rapid, cloning‐free construction and genomic integration of expression cassettes in Saccharomyces cerevisiae. …”
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“…Over a decade ago, the formation of neutrophil extracellular traps (NETs) was described as a novel mechanism employed by neutrophils to tackle infections. Currently applied methods for NETs release quantification are often limited by the use of unspecific dyes and technical difficulties. …”
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“…Probability-based inverse modeling method was shown feasible for locating single instantaneous source in IAQ events. To tackle more realistic sources of continuous release, this paper advances the method to identify continuously releasing single contaminant source. …”
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“…As specialised institutions that provide a stable locus of expertise, continuity of experience, scientific knowledge, and appropriate human, technical, and financial resources, national public health institutes (NPHIs) are well-prepared to tackle public health challenges. We describe how a collaboration between the NPHIs of England and South Africa built a mutually beneficial professional relationship to help implement the WHO International Health Regulations, build capacity for health protection, and promote the exchange of information, advice, and expertise. …”
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“…One of the most viable options to tackle the growing resistance to the antimalarial drugs such as artemisinin is to resort to synthetic drugs. …”
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“…Drawing insights from multiple disciplines is essential for finding integrative solutions that are required to tackle complex environmental problems. Human activities are causing unprecedented influence on global ecosystems, culminating in the loss of species and fundamental changes in the selective environments of organisms across the tree of life. …”
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“…With nearly 15 million people dying each year as a result of ID, most of them living in developing countries, there is need to find solutions to prevent and tackle infectious diseases in these communities. This book is devoted to infectious diseases and livelihoods in developing countries.…”
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“…In this paper, we propose an approach to tackle the problem of the automatic restoration of Arabic diacritics that includes three components stacked in a pipeline: a deep learning model which is a multi-layer recurrent neural network with LSTM and Dense layers, a character-level rule-based corrector which applies deterministic operations to prevent some errors, and a word-level statistical corrector which uses the context and the distance information to fix some diacritization issues. …”
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