“…In this work, we assume the use of a digital data packet network technology, namely WiFi, and tackle the problem of defining the exact placement for the relaying UAVs that creates an end-to-end channel with maximal delivery of data packets. …”
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“…Identifying key factors in the regulation of ATGL will help tackle hepatic lipid accumulation and related metabolic diseases. …”
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“…Challenges of accurate estimation lie in proper representation of these spatial-temporal factors and more importantly capturing the complex relationship among them for TTE. To tackle such challenges, we present a framework based on the fact that the travel time of each road segment is affected by its adjacent segments. …”
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“…An improved understanding of these mechanisms is crucial to guiding the design of new and more effective drugs to tackle these devastating diseases. In addition, we provide a comprehensive overview of proteasome inhibitors used in combination with other chemotherapeutic agents, as this is a key strategy to combat resistance.…”
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“…It was concluded that global distrust of dominating dentists must give way to person-centred professional strategies so that dentists and patients can tackle their dental anxiety-trust challenges, both in the public’s image of the dental profession and in clinical relationships. …”
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“…The causes of unmet needs can be traced back to early life, which underscores the importance of concerted efforts in family, education and long-term care policies to tackle unmet needs.…”
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“…We conclude it is vital to fully assess and optimise novel analytical microbiology tools using multiple individual urine samples, otherwise the high variation in matrix interference will compromise the clinical performance of these rapid diagnostics that are urgently needed to tackle the global threat of antimicrobial resistance.…”
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“…The biological barriers in vivo have limited the site-specific bioavailability and impeded therapeutic efficacy. To tackle these issues, nonspherical particles with a shape effect have attracted wide attention to affect the in vivo translocation of a drug delivery system. …”
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“…In this review, we discuss the different characteristics of BCSCs, and challenges to tackle BCSCs at cellular and molecular levels. The mechanisms of action and physicochemical properties of the current BCSC targeting agents are also covered. …”
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“…The efficacy of yoga as a therapy to tackle the direct and indirect cause of ailment in the management of PCOS is to be documented. …”
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“…One of the major obstacles in replacing the widely used zinc dialkyldithiophosphate (ZDDP) antiwear additive with a more environmentally friendly one is the difficulty of time-resolving the surface species resulting from its decomposition mechanism under high contact pressure and temperature. To tackle this issue, a newly developed miniature pin-on-disc tribotester was coupled with synchrotron X-ray absorption spectroscopy (XAS) to perform in situ tribological tests while examining the composition of the formed triboreactive films. …”
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“…[Image: see text] Herein, we report a study on the reactivity of three 1,3-diarylimidazolium-based fluoride reagents, with a general formula of [IPrH][F(HF)(n)] (n = 0, 1, or 2), that tackle the challenges of limited solubility, hygroscopicity, instability, and laborious preparation procedures of nucleophilic fluoride reagents. …”
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“…Implications are drawn on ways to tackle stress processes and help adolescents stay engaged with schoolwork during confinement.…”
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“…This article discusses whether the current strategies, most notably, vaccine donations by the international community and the COVID‐19 global access facility COVAX, offer meaningful solutions to tackle the problem. At the centre of our analysis, we compare the concepts of “donations” and “charity” with “vaccine equity” and the “empowerment” of poorer countries. …”
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“…By observing the role played by noise in other areas of natural sciences, where noise is used to excite the system away from false attractors, a new approach to tackle the dark forces of fake news is proposed.…”
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“…Understanding the functional impact of the diversity existing in TB-causing bacteria, as well as incorporating this diversity in TB research, will contribute to the development of better, more specific approaches to tackle TB.…”
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“…Existing bipartite network link prediction is mainly based on the global structure that cannot analyze the role of the local structure in link prediction. To tackle this problem, this paper proposes a deep link-prediction (DLP) method by leveraging the local structure of bipartite networks. …”
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“…The metric used is a weighted sum of the squared Euclidean distances in the feature and network spaces. To tackle the so-called curse of dimensionality, we extend this to a version that uses the cosine distances between entities and centers. …”
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“…Inflammasome-targeted therapeutic options might thus provide a promising strategy to tackle these debilitating diseases.…”
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“…While gait disturbances arising years after DBS surgery can be related to disease progression, early impairment of gait may be secondary to treatable causes and benefits from DBS reprogramming. In this review, we tackle the issue of gait disturbances in PD patients with DBS by discussing their neurophysiological basis, providing a detailed clinical characterization, and proposing a pragmatic programming approach to support their management.…”
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