“…The present article provides a picture of the current clinical applications of bioactive glasses, and depicts six relevant challenges deserving to be tackled in the near future. We hope that this work can be useful to both early-stage researchers, who are moving with their first steps in the world of bioactive glasses, and experienced scientists, to stimulate discussion about future research and discover new applications for glass in medicine.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the literature review, the majority of revised studies (44 studies) indicate that the trajectory based with variable air quality approach provides a promising framework for tackling the important question of inter- and intra-variability of individual exposure. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Engineered microbial communities are also extremely relevant to tackling some of today's grand societal challenges. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This task is usually approached as a supervised machine learning problem, where a label is to be predicted given some input data, such as the signals retrieved from different sensors. For tackling the human activity recognition problem in sensor network environments, in this paper we propose the use of deep learning (convolutional neural networks) to perform activity recognition using the publicly available OPPORTUNITY dataset. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This review describes several emerging, encouraging therapeutic approaches aimed at tackling the underlying causes of tau pathology in AD and other tauopathies that have recently reached the clinical development stage.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These include the risks of unintended consequences and the need to continually reformulate the concept of stigma, to ensure that tackling stigma at the structural, interpersonal, and intrapersonal levels become part of the core business of stakeholder organisations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…After implementing quality control and corrections, data was of variable quality. We tackled this by categorizing data as to providing quantitative or only qualitative information: • 50% and 59% of all CH(4) and N(2)O data, respectively, provided quantitative information above the detection limit. • We chose not to discard data providing only qualitative information, because they identify highest- and lowest-flux peak periods and indicate the variability of the fluxes, along different altitudes and under different climatic conditions. • We chose not to give fluxes below detection limit a quantitative value but to acknowledge them as values identifying periods with low fluxes.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The findings published so far point to a distinct metabolic phenotype in cancer stem cells, which might depend on the cancer type, the model system used or even the experimental design, and several controversies still need to be tackled. This Review describes the metabolic phenotype of cancer stem cells by addressing the main metabolic traits in different tumours, including glycolysis and oxidative, glutamine, fatty acid and amino acid metabolism. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…How to study the associations between these structural and functional layers is an open problem that involves novel conceptual ways of tackling this question. We here propose an extension of the Connectivity Independent Component Analysis (connICA) framework to identify joint structural-functional connectivity traits. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Development of ion-releasing implantable biomaterials is a valuable approach for advanced medical therapies. In the effort of tackling this challenge, we explored the feasibility of porous bioceramic scaffolds releasing copper ions, which are potentially able to elicit angiogenetic and antibacterial effects. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The above problems can be tackled by the feedforward compensation method that is proposed in this paper. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Strategies developed to ease the implementation of experimental set-ups anchored in the use of microfluidic devices will be briefly tackled. Finally, realistic considerations on the current advantages and limitation on the use of microfluidic devices for process intensification, as well as prospective near future developments in the field, will be presented.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…With the increasing popularity of smart ocean management, how to achieve the two-factor protection of public data resources in smart ocean management is a serious problem to be tackled. Furthermore, how to achieve both security and revocation is also a challenge for two-factor protection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The Internet, with the rise of the IoT, is one of the most powerful means of propagating a terrorist threat, and at the same time the perfect environment for deploying ubiquitous online surveillance systems. This paper tackles the problem of online surveillance, which we define as the monitoring by a security agency of a set of websites through tracking and classification of profiles that are potentially suspected of carrying out terrorist attacks. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Using this model, we show that mechanical parameters can be obtained that are consistent with both dual pipette aspiration and micropipette aspiration, a problem not successfully tackled so far. We estimate a cortex elastic modulus of E(c) ≈ 15 kPa, an effective cortex thickness of t(c) ≈ 0.3 μm, and an active tension of γ ≈ 0.4 nN/μm. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…There are some very interesting questions being tackled by researchers today as they pertain to altered metabolism in breast cancer. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This paper presents a novel approach that tackles the two aforementioned issues. Specifically, our approach includes two intertwined steps: (i) a Rapidly-Exploring Random Tree (RRT) search that allows a robot to identify unvisited locations, and to learn the GP parameters, and (ii) an RRT*-based informative path planning that guides the robot towards those locations by maximizing the information gathered while minimizing path cost. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Further research on the efficacy of short teacher-based programs would be worthwhile, given the limited financial and time resources of the schools, emphasizing the active and crucial role of teachers in tackling cyberbullying.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Vaginal and rectal microbicides hold great promise in tackling sexual transmission of HIV-1, but effective and safe products are yet to be approved and made available to those in need. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Focus should be redirected through a medical model towards elimination of the disease through tackling its causes and risk factors to address current and future caries initiation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso