“…By shedding light on the roles of ncRNAs in mediating intercellular communication, this review underscores their significance in orchestrating TME transformation and highlights their potential as novel therapeutic targets for effectively tackling glioma progression.…”
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“…While researchers have developed many approaches to tackling this problem, few have exploited the multi-data approach with a classical technique. …”
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“…This dual-discriminator approach ensures robust and comprehensive performance in tackling diverse snow conditions. The proposed model displays a superior ability to capture snow and object features within LiDAR point clouds. …”
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“…It showcases instances where ML effectively tackled critical care outcome-prediction challenges, including nonlinear relationships, class imbalances, missing data, and documentation variability, leading to enhanced results. …”
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“…Original articles from Pubmed, Embase and Cochrane, published until June 16(th) 2023, and tackling the effect of BMS on disease outcomes in patients with RA were included. …”
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“…In recent years, research for tackling the incidences of dengue infection has increased. …”
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“…The disease process is characterized by the activation of macrophages, which then release tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), accelerating tissue damage. Tackling tissue damage is a crucial target in the treatment of RA. …”
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“…Designing a robust direct compression (DC) formulation for an active pharmaceutical ingredient (API) with poor flow and compaction properties at a high API load is challenging. This study tackled two challenges: the unfavorable flow characteristics and tableting problems associated with a high-drug-loading canagliflozin (CNG), facilitating high-speed DC tableting. …”
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“…This study demonstrates the utility of an appreciative inquiry approach for understanding how complex systems like medical education institutions are innovatively tackling challenges around health equity. The richness of the themes that emerged consistently across focus group sessions and key informant interviews support the utility of the approach in furthering our understanding as to what is working to drive social accountability in some Canadian medical schools.…”
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“…RESULTS: In this work we propose a Bayesian nonparametric approach for tackling statistical problems related to EST surveys. …”
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“…Our results provide, for the first time, evidence that bistability and stochastic gene expression could be important for the development of “heterogeneity with an advantage” in mycobacteria and suggest strategies for tackling tuberculosis like targeting transitions from the low to the high rel expression state.…”
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“…There is presence of 'hot-spots' and very large differences persist between sub-regions. Only by tackling TB and HIV together will progress be made in reversing the burden of both diseases. …”
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“…Recently, several studies have tackled this challenge via a network-based approach, motivated by the observation that genes causing the same or similar diseases tend to lie close to one another in a network of protein-protein or functional interactions. …”
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“…BACKGROUND: Regular cycling has been shown to improve health and has a role in tackling the threats posed by obesity and inactivity. …”
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“…Improvements to intelligence systems, practitioner awareness and screening are essential in tackling this.…”
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“…This might be a result of more regard to injury prevention, less foul play and stricter refereeing. Tackling skills and fair play need to be improved to prevent contact injuries in training and matches. …”
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“…The model is able to reproduce and explain the main physiological features of multisensory integration in SC neurons and to describe how SC integrative capability – not present at birth – develops gradually during postnatal life depending on sensory experience with cross-modal stimuli. The second model tackles the problem of how tactile stimuli on a body part and visual (or auditory) stimuli close to the same body part are integrated in multimodal parietal neurons to form the perception of peripersonal (i.e., near) space. …”
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“…Very few studies have examined neural substrates associated with correct odor recognition, and none has tackled neural networks associated with incorrect odor recognition. …”
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“…Extracellular ATP and reactive astrocytes appear to be responsible for the activation of microglia which in turn release proinflammatory cytokines contributing further to the parkinsonian condition. In addition to tackling oxidative stress pathways we also suggest to reduce microglial and endothelial activation to support neuronal outgrowth.…”
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“…Furthermore, we studied how trains of synaptic potentials had lesser decay during periods of activity (UP states) than during silent periods (DOWN states), providing new experimental predictions. We next tackled the inverse question of what is the impact of modifying STD parameters on the emergent activity of the network, a question difficult to answer experimentally. …”
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