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15281por Shanmukhappa, Sanjana Chetana, Abraham, Rahul R., Venkatesh, Vinyas Shraffi, Abraham, Rithika R.“…Institutional support, adequate mentorship and an uplifting research environment can go a long way in motivating the doctors and tackling the challenges they face.…”
Publicado 2020
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15282por Baxevanis, Constantin N., Fortis, Sotirios P., Ardavanis, Alexandros, Perez, Sonia A.“…We highlight the importance of proper clinical design in terms of selected groups of patients, taking into consideration (a) changes in initially established standard-of-care treatments; (b) the appropriate follow-up period necessary to achieve meaningful results; (c) statistical considerations for the delay of treatment effects (i.e., time for development of an effective immune response), thus excluding irrelevant early events; and (d) appropriate biomarkers that could guide vaccinations with clinical benefits to patients. Tackling the aforementioned challenges, therapeutic vaccines could take their rightful place in the immunotherapy hall of fame. …”
Publicado 2020
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15283“…A good understanding of the poor-non-poor gap in childhood development of severe wasting (SW) is a must in tackling the age-long critical challenge to health outcomes of vulnerable children in low- and middle-income countries (LMICs). …”
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15284“…Behavioural or educational interventions are therefore likely to be less effective in tackling food insecurity and poor nutrition among people on a low income; policies focusing on structural drivers, including poverty and geographical access to food, are needed.…”
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15285por Soltan, MA, Crowley, LE, Melville, CR, Varney, J, Cassidy, S, Mahida, R, Grudzinska, FS, Parekh, D, Dosanjh, DP, Thickett, DR“…BACKGROUND: Internationally, researchers have called for evidence to support tackling health inequalities during the severe acute respiratory syndrome coronavirus 2 (COVID19) pandemic. …”
Publicado 2021
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15286“…CONCLUSION: FLANNEL effectively combines state-of-the-art convolutional neural network classification models and tackles class imbalance with focal loss to achieve better performance on COVID-19 detection from x-rays.…”
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15287por Tonkovic, Petar, Kalajdziski, Slobodan, Zdravevski, Eftim, Lameski, Petre, Corizzo, Roberto, Pires, Ivan Miguel, Garcia, Nuno M., Loncar-Turukalo, Tatjana, Trajkovik, Vladimir“…We provide an overview of the state of the art metagenomic classification methods, as well as the challenges researchers face when tackling this complex problem. The end goal of this review is to help researchers be up to date with current trends, as well as identify opportunities for further research and improvements. …”
Publicado 2020
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15288“…This is more difficult in an inpatient setting with prescribing often being done by a resident, but the decisions regarding antimicrobials are often made by the attending physician. This concept was tackled at a tertiary children’s hospital but was a manual and time-consuming process. …”
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15289por Nash, Kirsty L., Alexander, Karen, Melbourne-Thomas, Jess, Novaglio, Camilla, Sbrocchi, Carla, Villanueva, Cecilia, Pecl, Gretta T.“…The oceans face a range of complex challenges for which the impacts on society are highly uncertain but mostly negative. Tackling these challenges is testing society’s capacity to mobilise transformative action, engendering a sense of powerlessness. …”
Publicado 2021
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15290por Zecha, Jana, Lee, Chien-Yun, Bayer, Florian P., Meng, Chen, Grass, Vincent, Zerweck, Johannes, Schnatbaum, Karsten, Michler, Thomas, Pichlmair, Andreas, Ludwig, Christina, Kuster, Bernhard“…As the COVID-19 pandemic continues to spread, thousands of scientists around the globe have changed research direction to understand better how the virus works and to find out how it may be tackled. The number of manuscripts on preprint servers is soaring and peer-reviewed publications using MS-based proteomics are beginning to emerge. …”
Publicado 2020
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15291por Liu, Tao, Zheng, Zheng, Sha, Xiaoyan, Liu, Huishu, Zheng, Wenjing, Su, Huanxing, Xu, Guiyun, Su, Kuan-Pin, So, Kwok-Fai, Lin, Kangguang“…Obstetricians and midwives, among other medical staff, are tackling COVID-19 and are under immense psychological stress. …”
Publicado 2020
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15292“…Pituitary adenoma surgeries are common in neurosurgical setup. Majority are tackled by a transsphenoidal route either by endoscopic or microscopic aid. …”
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15293por Sikana, Lwitiko, Lembo, Tiziana, Hampson, Katie, Lushasi, Kennedy, Mtenga, Sally, Sambo, Maganga, Wight, Daniel, Coutts, Jane, Kreppel, Katharina“…Interventions tackling zoonoses require an understanding of healthcare patterns related to both human and animal hosts. …”
Publicado 2021
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15294por Rabinovich, Jorge E., Alvarez Costa, Agustín, Muñoz, Ignacio J., Schilman, Pablo E., Fountain-Jones, Nicholas M.“…E.g., what combination of exposure time and temperature is important for a species thermal tolerance is difficult to judge a priori. We tackled this problem using an active learning approach that utilized machine learning methods to guide thermal tolerance experimental design for three kissing-bug species: Triatoma infestans, Rhodnius prolixus, and Panstrongylus megistus (Hemiptera: Reduviidae: Triatominae), vectors of the parasite causing Chagas disease. …”
Publicado 2021
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15295por Warr, William, Aveyard, Paul, Albury, Charlotte, Nicholson, Brian, Tudor, Kate, Hobbs, Richard, Roberts, Nia, Ziebland, Sue“…Strategies to implement clinical guidelines need to make tackling obesity a clinical priority. Training to overcome interactional difficulties, regular weighing of patients and changing expectations and understanding of weight loss interventions are also probably required.…”
Publicado 2020
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15296por Rico-González, Markel, Pino-Ortega, José, Clemente, Filipe Manuel, Rojas-Valverde, Daniel, Arcos, Asier Los“…Pressure (GC-GC) was greater in shots on goal than in tackles during professional futsal matches. Area variables were reduced to occupied space, exploration space and dominant area. …”
Publicado 2020
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15297“…In this paper, we examine whether and how adaptation plans from C40 member cities address inequality in risk, by planning actions to reduce hazard exposure or tackling the drivers of social vulnerability. C40 is a network of 94 of the world's cities fostering policies to address climate change. …”
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15298“…MPC regulation is therefore central to tackling glycolysis in tumors. ABSTRACT: Pyruvate is a key molecule in the metabolic fate of mammalian cells; it is the crossroads from where metabolism proceeds either oxidatively or ends with the production of lactic acid. …”
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15299“…A detailed understanding of how M. tuberculosis enters into and exits out of dormancy, is necessary in order to develop new strategies for tackling tuberculosis. Omics methodologies are unsupervised and unbiased to any hypothesis, making them useful tools for the discovery of new drug targets. …”
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15300“…On the other hand, they suffer from a deficiency in predicting cyber-crime and cyber-attack methods. This problem can be tackled by identifying an attack and the perpetrator of such attack, using actual data. …”
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