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15781“…Currently, there is no effective vaccine for tackling the ongoing COVID-19 pandemic caused by SARS-CoV-2 with the occurrence of repeat waves of infection frequently stretching hospital resources beyond capacity. …”
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15782por Liu, Bi, Shen, Yunzhu, Huang, Huafang, Croce, Kimiko Della, Wu, Min, Fan, Yingjuan, Liu, Yang, Xu, Jianhua, Yao, Guang“…Such dual targeting therapeutic agents, however, are lacking in the clinic. To start tackling this problem, encouraged by the promising anticancer effects of a set of curcumin derivatives in our earlier studies, we examined in this work the effects of a 4-arylmethyl curcumin derivative (C212) in eliminating both growing and quiescent leukemia cells. …”
Publicado 2020
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15783por Paling, Steven, Lambert, Jennifer, Clouting, Jasper, González-Esquerré, Júlia, Auterson, Toby“…CONCLUSIONS: These results suggest that tackling patient flow and capacity in the wider hospital, particularly very high bed occupancy levels and patient discharge, is important to reduce ED waiting times and improve patient outcomes.…”
Publicado 2020
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15784“…There was a lot of support for ‘decreasing healthcare costs’, ‘tackling increased health demand’ and ‘improving healthcare effectiveness’ as main goals of ESP. …”
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15785por Jadnanansing, Raj, Blankers, Matthijs, Dwarkasing, Rudi, Etwaroo, Kajal, Lumsden, Vincent, Dekker, Jack, Bipat, Robbert“…It is therefore of paramount importance to develop therapeutic strategies with the aim of tackling this physically and mentally disabling disorder. …”
Publicado 2021
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15786por Nascimbeni, R., Amato, A., Cirocchi, R., Serventi, A., Laghi, A., Bellini, M., Tellan, G., Zago, M., Scarpignato, C., Binda, G. A.“…The following 5 issues were tackled: 1) Criteria to decide between conservative and surgical treatment in case of perforated diverticulitis with peritonitis; 2) Criteria or scoring system to choose the most appropriate surgical option when diffuse peritonitis is confirmed 3); The appropriate surgical procedure in hemodynamically stable or stabilized patients with diffuse peritonitis; 4) The appropriate surgical procedure for patients with generalized peritonitis and septic shock and 5) Optimal medical therapy in patients with generalized peritonitis from diverticular perforation before and after surgery. …”
Publicado 2020
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15787por Metwally, Ammal M., Elmosalami, Dalia M., Elhariri, Hazem, El Etreby, Lobna A., Aboulghate, Ahmed, El-Sonbaty, Marwa M., Mohsen, Amira, Saleh, Rehan M., Abdel-Latif, Ghada A., Samy, Sahar, El Deeb, Sherif E., Fathy, Asmaa M., Salah, Mohab M., Abdel Mawla, Mohamed A., Imam, Hanaa M., Ibrahim, Nihad A., Shaaban, Fatma A., Elamir, Reham Y., Abdelrahman, Mohamed, El-Sayed, Manal H.“…CONCLUSION: Egypt would be closer to HCV elimination when cost-effective strategies are directed not towards creating awareness, perceived risk or motivation to change- (at an acceptable level)- but towards motivating adopting risk-reduction behaviors for HCV, tackling misconceptions and reinforcement of social support.…”
Publicado 2021
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15788por Herklots, Tanneke, D'haene, Lara, Mbarouk, Khairat Said, Rajhy, Mubina, Couperus, Simone, Meguid, Tarek, Franx, Arie, Koster, Maria P H, Jacod, Benoit“…INTRODUCTION: Tackling substandard maternity care in health facilities requires engaging women’s perspectives in strategies to improve outcomes. …”
Publicado 2021
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15789por Alzubaidi, Laith, Zhang, Jinglan, Humaidi, Amjad J., Al-Dujaili, Ayad, Duan, Ye, Al-Shamma, Omran, Santamaría, J., Fadhel, Mohammed A., Al-Amidie, Muthana, Farhan, Laith“…Despite it has been contributed several works reviewing the State-of-the-Art on DL, all of them only tackled one aspect of the DL, which leads to an overall lack of knowledge about it. …”
Publicado 2021
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15790por Baskin, Cleo, Zijlstra, Geiske, McGrath, Mike, Lee, Caroline, Duncan, Fiona Helen, Oliver, Emily J, Osborn, David, Dykxhoorn, Jen, Kaner, Eileen F S, LaFortune, Louise, Walters, Kate R, Kirkbride, James, Gnani, Shamini“…Common components included a focus on tackling social isolation, using lay health workers from within the community, signposting and overcoming structural barriers to access. …”
Publicado 2021
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15791por Awad, Emmanuelle, Haddad, Chadia, Sacre, Hala, Hallit, Rabih, Soufia, Michel, Salameh, Pascale, Obeid, Sahar, Hallit, Souheil“…Given the lack of studies tackling bullying perpetration in Lebanon, this study aims to identify and target risk factors of bullying perpetration among Lebanese adolescents, which would serve future prevention and intervention programs. …”
Publicado 2021
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15792por Negatou, Mariamawit, Ouedraogo, Mady, Donnen, Philippe, Paul, Elisabeth, Samadoulougou, Sekou, Kirakoya-Samadoulougou, Fati“…Maintaining FHP and tackling the barriers should be considered by policy makers to increase care-seeking.…”
Publicado 2021
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15793“…Our middle-range theory showed that to be effective in tackling social inequalities in health, actions must address structural determinants at the macro-systemic level. …”
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15794por Fenn, Bridget, Myatt, Mark, Mates, Emily, Black, Robert E, Wilkinson, Caroline, Khara, Tanya“…Broadening the scope of interventions aimed at children in camps is essential when tackling malnutrition with increased efforts essential during periods of wider food assistance shortages.…”
Publicado 2021
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15795por Sathappan, Selva Muthu Kumaran, Jeon, Young Seok, Dang, Trung Kien, Lim, Su Chi, Shao, Yi-Ming, Tai, E Shyong, Feng, Mengling“…Background Diabetes mellitus (DM) is an important public health concern in Singapore and places a massive burden on health care spending. Tackling chronic diseases such as DM requires innovative strategies to integrate patients' data from diverse sources and use scientific discovery to inform clinical practice that can help better manage the disease. …”
Publicado 2021
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15796“…Simultaneously, spatial aspects, alongside the non-spatial, seemed crucial in tackling complex poverty profiles, resource-scarcity, and vulnerabilities of slums. …”
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15797por Yap, Kah Min, Sekar, Mahendran, Seow, Lay Jing, Gan, Siew Hua, Bonam, Srinivasa Reddy, Mat Rani, Nur Najihah Izzati, Lum, Pei Teng, Subramaniyan, Vetriselvan, Wu, Yuan Seng, Fuloria, Neeraj Kumar, Fuloria, Shivkanya“…However, 1) the lack of therapeutic options for metastatic breast cancer, 2) resistance to drug therapy and 3) the lack of more selective therapy for triple-negative breast cancer are some of the major challenges in tackling breast cancer. Given the safe nature of natural products, numerous studies have focused on their anti-cancer potentials. …”
Publicado 2021
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15798Pattern and pace of morphological change due to variable human impact: the case of Japanese macaquespor Geiger, Madeleine“…This species is ideal for tackling such questions because different wild, wild-provisioned, and captive populations have been monitored and collected over seven decades. …”
Publicado 2021
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15799por Edge, Daniel, Newbold, Alexandra, Ehring, Thomas, Rosenkranz, Tabea, Frost, Mads, Watkins, Edward R.“…DISCUSSION: This trial aims to better understand the benefits of tackling RNT via an mobile phone app intervention in young people. …”
Publicado 2021
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15800por Fernandes, G. S., Spiers, A., Vaidya, N., Zhang, Y., Sharma, E., Holla, B., Heron, J., Hickman, M., Murthy, P., Chakrabarti, A., Basu, D., Subodh, B. N., Singh, L., Singh, R., Kalyanram, K., Kartik, K., Kumaran, K., Krishnaveni, G., Kuriyan, R., Kurpad, S., Barker, G. J., Bharath, R. D., Desrivieres, S., Purushottam, M., Orfanos, D. P., Toledano, M. B., Schumann, G., Benegal, V.“…The results suggest enhancing current ACE resilience programmes and ‘trauma-informed’ approaches to tackling longer-term impact of ACEs in India. FUNDING: Newton Bhabha Grant jointly funded by the Medical Research Council, UK (MR/N000390/1) and the Indian Council of Medical Research (ICMR/MRC-UK/3/M/2015-NCD-I). …”
Publicado 2021
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