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1961por Monasterio Astobiza, Aníbal“…In this short paper, I wish to tackle how these three factors have added up to give rise to a negative public understanding of science in times of a health crisis, such as the current Covid-19 pandemic and finally, how to confront all these problems.…”
Publicado 2021
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1962“…The present minireview focuses on analyzing current and potential strategies to tackle problems and realize the SERS performance necessary for translation to practical applications.…”
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1963“…In this paper, we call for a global approach and the establishment of a World Health Organization (WHO) Expert Advisory Committee on Regenerative Medicine to tackle this issue and provide guidance. The WHO committee can harmonize national regulations; promote regulatory approaches responsive to unmet patient needs; and formulate an education campaign against misinformation. …”
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1964por Coutinho, Janine Giuberti, Martins, Ana Paula Bortoletto, Preiss, Potira V., Longhi, Lorenza, Recine, Elisabetta“…The COVID-19 pandemic overwhelms this scenario, highlighting the urgency for improvements in governance spaces and regulatory measures that can tackle the advance of large corporations, which act exclusively based on their private interests.…”
Publicado 2021
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1965“…Finally, we look at the interplay of mechanics and developmental robustness and discuss open questions in the field, as well as novel approaches that will help tackle them in the future.…”
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1966“…The contribution of the article is the following: • Clearly defined strategies to follow for a systematic literature review in computer science research, and • Algorithmic method to tackle a systematic literature review.…”
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1967“…However, it is unclear to what extent their predictions agree. In this article, we tackle this problem by comparing the two accounts with respect to a common set of predictions about the effort required to acquire categories. …”
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1968“…However, the clinical comprehension of cardiac irAEs remains limited and guidelines are inadequate for cardio-oncologists to tackle the problem. In this review, we have summarized current classifications of, manifestations of, potential mechanisms of, and treatment for ICI-related myocardial injury in order to provide some clues for the understanding of cardiac irAEs in clinical work.…”
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1969por Kuśnierz, Jacek, Padulano, Vincenzo Eduardo, Malawski, Maciej, Burkiewicz, Kamil, Saavedra, Enric Tejedor, Alonso-Jordá, Pedro, Pitt, Michael, Avati, Valentina“…Such a managed approach may not be the only viable way to tackle them and an interesting alternative could be provided by serverless architectures, to enable an even larger scaling potential. …”
Publicado 2022
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1970por Kansal, Raghav, Li, Anni, Duarte, Javier, Chernyavskaya, Nadezda, Pierini, Maurizio, Orzari, Breno, Tomei, Thiago“…There has been a recent explosion in research into machine-learning-based generative modeling to tackle computational challenges for simulations in high energy physics (HEP). …”
Publicado 2022
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1971por Garcia, Ana Rita, Mendes, Avilson, Custódia, Carlos, Faria, Cláudia C., Barata, João T., Malhó, Rui, Figueira, Inês, Brito, Maria Alexandra“…This work revealed EGFR/PI3K dual inhibitors as strong candidates to tackle brain metastatic TNBC cells.…”
Publicado 2023
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1972“…The findings also suggest that participating actors in the ecosystem should utilise wider knowledge and experience to tackle complex societal challenges associated with well-being. …”
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1973por Sahanic, Sabina, Hilbe, Richard, Dünser, Christina, Tymoszuk, Piotr, Löffler-Ragg, Judith, Rieder, Dietmar, Trajanoski, Zlatko, Krogsdam, Anne, Demetz, Egon, Yurchenko, Maria, Fischer, Christine, Schirmer, Michael, Theurl, Markus, Lener, Daniela, Hirsch, Jakob, Holfeld, Johannes, Gollmann-Tepeköylü, Can, Zinner, Carl P., Tzankov, Alexandar, Zhang, Shen-Ying, Casanova, Jean-Laurent, Posch, Wilfried, Wilflingseder, Doris, Weiss, Guenter, Tancevski, Ivan“…OBJECTIVE: We investigated the engagement of SARS-CoV-2 with TLR4 in order to better understand how to tackle hyperinflammation in COVID-19. METHODS: We combined RNA-sequencing data of human lung tissue and of bronchoalveolar lavage fluid cells derived from COVID-19 patients with functional studies in human macrophages using SARS-CoV-2 spike proteins and viable SARS-CoV-2. …”
Publicado 2023
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1974por Meng, Arnaud, Marchet, Camille, Corre, Erwan, Peterlongo, Pierre, Alberti, Adriana, Da Silva, Corinne, Wincker, Patrick, Pelletier, Eric, Probert, Ian, Decelle, Johan, Le Crom, Stéphane, Not, Fabrice, Bittner, Lucie“…As the study of holobiont meta-transcriptomes is affected by challenges invoked above, we propose an innovative bioinformatic approach to tackle such difficulties and tested it on marine models as a proof of concept. …”
Publicado 2018
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1975por Curcio, Alberto, Silva, Amanda K. A., Cabana, Sonia, Espinosa, Ana, Baptiste, Benoit, Menguy, Nicolas, Wilhelm, Claire, Abou-Hassan, Ali“…However, there is still room for improvement when it comes to the development of multi-functional nanoparticle agents merging a plurality of therapeutic functions to tackle tumors simultaneously by synergic mechanisms. …”
Publicado 2019
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1976“…BACKGROUND: Addressing food portion sizes is a key untapped opportunity to help tackle obesity. This study sought to inform the agenda of a national movement involving diverse sectors to manage portion sizes in packaged foods, restaurants, cafeterias and prepared foods in grocery stores. …”
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1977por Boukhris, Marouane, Hillani, Ali, Moroni, Francesco, Annabi, Mohamed Salah, Addad, Faouzi, Ribeiro, Marcelo Harada, Mansour, Samer, Zhao, Xiaohui, Ybarra, Luiz Fernando, Abbate, Antonio, Vilca, Luz Maria, Azzalini, Lorenzo“…Innovative approaches that leverage modern technologies to tackle the COVID-19 pandemic have been introduced, which include telemedicine, dissemination of educational material over social media, smartphone apps for case tracking, and artificial intelligence for pandemic modelling, among others. …”
Publicado 2020
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1978por Fuentes-Fayos, Antonio C, Vázquez-Borrego, Mari C, Jiménez-Vacas, Juan M, Bejarano, Leire, Pedraza-Arévalo, Sergio, L.-López, Fernando, Blanco-Acevedo, Cristóbal, Sánchez-Sánchez, Rafael, Reyes, Oscar, Ventura, Sebastián, Solivera, Juan, Breunig, Joshua J, Blasco, María A, Gahete, Manuel D, Castaño, Justo P, Luque, Raúl M“…Remarkably, SRSF3 is directly associated with glioblastoma development, progression, aggressiveness and patient survival and represents a novel potential therapeutic target to tackle this devastating pathology.…”
Publicado 2020
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1979“…Sustainable management of manure via recycling is an effective means to tackle the problem. Based on field interviews in China, multiple case studies were employed to investigate alternative manure management systems. …”
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1980por Gontariuk, Marie, Krafft, Thomas, Rehbock, Cassandra, Townend, David, Van der Auwermeulen, Loth, Pilot, Eva“…Results: This study demonstrated that the limited EU mandate in health hinders proper actions to prevent and tackle infectious disease outbreaks, such as the COVID-19 pandemic. …”
Publicado 2021
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