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  1. 17721
    “…In addition, we choose a popular seaweed extract—fucoidan was extracted from the same brown algae—Sargassum aquifolium collected from Taiwan-Pingtung-Kenting-Chuanfan Rock. In this research, we used acid hydrolysis to prepared two different molecular weight fucoidan, the small molecular fucoidan (Fus) as drug, and the molecular weight approximately 1 kDa fucoidan (Ful) as the nanoparticle gatekeeper, and as targeting molecule for overexpressed P-selectin on the surface of the metastatic tumors. …”
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    Fucoidan with three functions extracted from Sargassum aquifolium integrated rice-husk synthesis dual-imaging mesoporous silica nanoparticle
  2. 17722
    “…METHODS: Audio recordings of road accidents in Taipei City, Taiwan, in 2018 were obtained and randomly sampled. …”
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    Machine Learning–Based Text Analysis to Predict Severely Injured Patients in Emergency Medical Dispatch: Model Development and Validation
  3. 17723
    “…METHODS: This nationwide, population-based, retrospective cohort study collected patients’ data between 1999 and 2013 from the National Health Insurance Research Database in Taiwan. A total of 9,235 patients were included. Using 1:4 propensity scoring, 1,847 patients were enrolled in the optic neuritis group and 7,388 in the non-optic neuritis group according to age, sex, comorbidities, and corticosteroid use. …”
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    Risk of Autoimmune Diseases Following Optic Neuritis: A Nationwide Population-Based Cohort Study
  4. 17724
    “…The cross-sectional data were obtained from the Taiwan Environmental Survey for Toxicants conducted in 2013. …”
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    Mediation effects of thyroid function in the associations between phthalate exposure and lipid metabolism in adults
  5. 17725
    “…MATERIAL AND METHODS: A nationwide population-based retrospective cohort study was conducted using medical records of the selected children from the Taiwan National Health Insurance Research Database. …”
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    Increased non-typhoidal Salmonella hospitalizations in transfusion-naïve thalassemia children: a nationwide population-based cohort study
  6. 17726
    “…METHODS: We included patients with AIS from the Taiwan Stroke Registry (TSR) during 2006–2016 as the present study population. …”
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    CHA2DS2-VASc score as an independent outcome predictor in patients hospitalized with acute ischemic stroke
  7. 17727
    “…METHODS: This population-based cohort study was conducted using data from Taiwan's single-payer national health insurance and cancer registry databases. …”
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    Human Papillomavirus Is Associated With Adenocarcinoma of Lung: A Population-Based Cohort Study
  8. 17728
    “…METHODS: This randomized, double-blind, multicenter, phase II trial recruited patients from eight medical centers in Taiwan. Patients with intractable diabetic foot and leg ulcers (Wagner Grade 1–3 without active osteomyelitis) were randomly assigned (2:1) to receive topical ENERGI-F703 gel or vehicle gel twice daily for 12 weeks or until complete ulcer closure. …”
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    ENERGI-F703 gel, as a new topical treatment for diabetic foot and leg ulcers: A multicenter, randomized, double-blind, phase II trial
  9. 17729
    “…Moreover, boys (60.90%) presented poorer CPF than girls (74.22%, p < 0.001). CONCLUSION: In Taiwan, patients with rTOF had poorer CPF than healthy peers. …”
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    Differences in Cardiopulmonary Fitness Between Boy and Girls With Repaired Tetralogy of Fallot
  10. 17730
    “…METHODS: This randomized, open‐label, phase 3 study was conducted at 36 medical centers in China (mainland), Malaysia, South Korea, and Taiwan. Patients were randomly assigned 1:1 to 200 mg of pembrolizumab intravenously every 3 weeks for ≤2 years or 80 mg/m(2) of paclitaxel intravenously every week. …”
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    Pembrolizumab versus paclitaxel for previously treated advanced gastric or gastroesophageal junction cancer (KEYNOTE‐063): A randomized, open‐label, phase 3 trial in Asian patients
  11. 17731
    “…In this retrospective nested case-control study, we identified 11 872 treatment-naïve patients with chronic HCV between 2001 and 2013 from Taiwan National Health Insurance Research Database and divided them into patients with (cases) and without cirrhosis (controls). …”
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    Long-term impact of certain coexisting extrahepatic unisystem and multisystem manifestations on trends in incidence of liver cirrhosis in treatment-naïve patients with chronic hepatitis C: A nested case-control study
  12. 17732
    “…Methods: This was a population-based cohort study utilizing Taiwan Longitudinal Health Insurance Database (LHID2010). …”
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    Risk of peripheral artery disease and stroke in migraineurs with or without aura: a nationwide population-based cohort study
  13. 17733
    por Tseng, Chin-Hsiao
    Publicado 2022
    “…Materials and methods: A total of 261,838 males, mean age 52.39 years (SD: 11.39), with a new-onset type 2 diabetes mellitus in 1999–2009 were identified from Taiwan’s National Health Insurance. Among them, 175,171 were metformin initiators [metformin (+)] and 86,667 were non-metformin initiators [metformin (−)] in the initial 12-month prescriptions of antidiabetic drugs. …”
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    Metformin’s effects on varicocele, erectile dysfunction, infertility and prostate-related diseases: A retrospective cohort study
  14. 17734
    “…This study was conducted to investigate if post-resuscitation diastolic blood pressure (DBP) is a favorable prognostic factor. METHODS: Using TaIwan Network of Targeted Temperature ManagEment for CARDiac Arrest (TIMECARD) registry, we recruited adult patients who received targeted temperature management in nine medical centers between January 2014 and September 2019. …”
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    Post-resuscitation diastolic blood pressure is a prognostic factor for outcomes of cardiac arrest patients: a multicenter retrospective registry-based analysis
  15. 17735
    “…Worldwide projections (based only on climate variables) revealed few marginal areas in 2050 only in México for P. martinezii, and several large areas (p ≥ 0.5) for P. mexicana around the world (all outside México), especially on the Himalayas in India and the Chungyang mountains in Taiwan with highly suitable (p ≥ 0.8) climate habitats in current and future (2050) conditions. …”
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    Assisted migration and the rare endemic plant species: the case of two endangered Mexican spruces
  16. 17736
    “…We included 4881 subjects who underwent voluntary health examination at Mackay Memorial Hospital, Taiwan between 2014 and 2019. Participants were categorized into the low-risk (<5%), borderline-risk (5%–7.4%), intermediate-risk (7.5%–19.9%), and high-risk (≥20%) groups based on the 10-year risk for ASCVD. …”
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    Risk assessment indicators and brachial-ankle pulse wave velocity to predict atherosclerotic cardiovascular disease
  17. 17737
    “…CASE PRESENTATION: Among the 184 childhood-onset SLE patients regularly followed in a tertiary medical center in Taiwan, 7 cases (3.8%) of which onset ≦ 5 years of age were identified for characteristic review and genetic analysis. …”
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    Characteristics and genetic analysis of patients suspected with early-onset systemic lupus erythematosus
  18. 17738
    “…To unravel more biodiversity within Frankia cluster-2 and predict routes of dispersal from Gondwana, we sequenced and analysed the MAGs of Frankia cluster-2 from Coriaria japonica and Coriaria intermedia growing in Japan, Taiwan and the Philippines. Phylogenetic analyses indicate there is a clear split within Frankia cluster-2, separating a continental from an island lineage. …”
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    A tale of two lineages: how the strains of the earliest divergent symbiotic Frankia clade spread over the world
  19. 17739
    “…METHODS: This nationwide, retrospective cohort study used data from the Taiwan National Health Insurance Research Database, enrolled a total of 90,731 non-valvular atrial fibrillation patients receiving rivaroxaban, dabigatran, apixaban or edoxaban from January 1st, 2012 to December 31st, 2017. …”
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    Concurrent use of statins decreases major bleeding and intracerebral hemorrhage in non-valvular atrial fibrillation patients taking direct oral anticoagulants—A nationwide cohort study
  20. 17740
    “…Based on trp36 sequence analysis, four E. canis genogroups, United States (US), Taiwan (TWN), Brazil (BR) and Costa Rica (CR), have been identified. …”
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    Novel Ehrlichia canis genogroup in dogs with canine ehrlichiosis in Cuba
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