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73781por Jimeno Yepes, Antonio Jose, Plaza, Laura, Carrillo-de-Albornoz, Jorge, Mork, James G, Aronson, Alan R“…In addition, this combination improves the performance of a state-of-the-art MeSH indexer. Concerning the machine learning algorithms, we find that those that are more resilient to class imbalance largely obtain better performance. …”
Publicado 2015
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73782“…In order to distinguish transmembrane proteins in the proteome as well as for topology prediction, we used a newly developed consensus method (CCTOP) that incorporates recent state of the art methods, with tested accuracies on a novel human benchmark protein set. …”
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73783“…AIM: This study assessed the prevalence and predictors of ED among men on anti-retro viral therapies (ART) in a Nigerian population. SUBJECTS AND METHODS: It was a descriptive cross-sectional survey among 234 HIV-positive men on anti-retroviral therapy selected using stratified sampling method after excluding for co-morbidities. …”
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73784por Glenn, Thomas C., Martin, Neil A., Horning, Michael A., McArthur, David L., Hovda, David A., Vespa, Paul, Brooks, George A.“…To that end, we utilized dual isotope tracer [6,6-(2)H2]glucose, that is, D2-glucose, and [3-(13)C]lactate techniques involving arm vein tracer infusion along with simultaneous cerebral (arterial [art] and jugular bulb [JB]) blood sampling. Traumatic brain injury (TBI) patients with nonpenetrating brain injuries (n=12) were entered into the study following consent of patients' legal representatives. …”
Publicado 2015
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73785por Ferrarotti, Ilaria, Poplawska-Wisniewska, Beata, Trevisan, Maria Teresa, Koepke, Janine, Dresel, Marc, Koczulla, Rembert, Ottaviani, Stefania, Baldo, Raffaele, Gorrini, Marina, Sala, Giorgia, Cavallon, Luana, Welte, Tobias, Chorostowska-Wynimko, Joanna, Luisetti, Maurizio, Janciauskiene, Sabina“…We illustrate the need for confirmation of Z A1AT values by “state of the art” method. Clinicians should consider a more in-depth investigation of A1ATD in patients when they exhibit serum polymers and low α1-globulin protein levels by SPE.…”
Publicado 2015
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73786“…FINDINGS: The study included 37 PLHIV with DM and 37 PLHIV without DM and both groups were treated with Anti-Retroviral Therapy (ART). The median age was 47 years (IQR: 41-55years) for PLHIV-DM as compared to 40 years (IQR: 35–45.5 years) for PLHIV (p<0.0001). …”
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73787por Enawgaw, Bamlaku, Alem, Meseret, Melku, Mulugeta, Addis, Zelalem, Terefe, Betelihem, Yitayew, Gashaw“…METHODS: A cross-sectional study was conducted on 265 HIV infected children from February to June 2013 on HIV infected children attending Gondar university Hospital ART clinic. The study subjects were selected with systematic random sampling technique. …”
Publicado 2015
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73788por Hitti, Jane, Halvas, Elias K, Zheng, Lu, Panousis, Constantinos G, Kabanda, Joseph, Taulo, Frank, Kumarasamy, Nagalingeswaran, Pape, Jean William, Lalloo, Umesh, Sprenger, Heather, Klingman, Karin L, Chan, Ellen S, McMahon, Deborah, Mellors, John W“…At entry mothers had CD4>250/μL and were ART-naïve except for antenatal ZDV per local standard of care. …”
Publicado 2014
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73789por Kharsany, Ayesha BM, Cawood, Cherie, Khanyile, David, Grobler, Anneke, Mckinnon, Lyle R., Samsunder, Natasha, Frohlich, Janet A, Abdool Karim, Quarraisha, Puren, Adrian, Welte, Alex, George, Gavin, Govender, Kaymarlin, Toledo, Carlos, Chipeta, Zawadi, Zembe, Lycias, Glenshaw, Mary T, Madurai, Lorna, M Deyde, Varough, Bere, Alfred“…Antiretroviral therapy (ART) access, HIV-1 RNA viral load, and CD4 cell counts in HIV positive individuals will assess the effectiveness of the HIV treatment cascade. …”
Publicado 2015
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73790por Ghoshal, Asish, Shankar, Raghavendran, Bagchi, Saurabh, Grama, Ananth, Chaterji, Somali“…CONCLUSIONS: We have developed an efficient SVM-based model for miRNA target prediction using recent CLIP-seq data, demonstrating superior performance, evaluated using ROC curves, specifically about 20 % better than the state-of-the-art, for different species (human or mouse), or different target types (canonical or non-canonical). …”
Publicado 2015
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73791por Aalbers, Teun, Baars, Maria AE, Qin, Li, de Lange, Annet, Kessels, Roy PC, Olde Rikkert, Marcel GM“…CONCLUSIONS: This study will add to the body of evidence on the effectiveness of eHealth intervention programs with the combined use of state-of-the-art applied games and established behavior change techniques. …”
Publicado 2015
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73792por Inoue, Osamu, Hamatani, Toshio, Susumu, Nobuyuki, Yamagami, Wataru, Ogawa, Seiji, Takemoto, Takashi, Hirasawa, Akira, Banno, Kouji, Kuji, Naoaki, Tanaka, Mamoru, Aoki, Daisuke“…Introduction of infertility treatment including assisted reproductive technology (ART) soon after achieving tumor disappearance by MPA would therefore be beneficial for patients with disease recurrence, thin endometrium, or a higher age of pregnancy permission. …”
Publicado 2016
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73793por Cox, Janneke A, Kiggundu, Daniel, Elpert, Lana, Meintjes, Graeme, Colebunders, Robert, Alamo, Stella“…RESULTS: 1028 deaths were included; 38% of these individuals were on antiretroviral therapy (ART). The estimated mortality rate dropped from 21.86 deaths/100 person years of follow-up (PYFU) in 2002 to 1.75/100 PYFU in 2012. …”
Publicado 2016
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73794“…Particularly, in the past decade, the application of the state-of the-art metabolomics and genomics technologies has revealed the remarkable plasticity of tumor metabolism and bioenergetics. …”
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73795por Evans, A. L., Singh, N. J., Friebe, A., Arnemo, J. M., Laske, T. G., Fröbert, O., Swenson, J. E., Blanc, S.“…Do climatic factors, an internal biological clock, or physiological processes dominate? Using state-of-the-art tracking and monitoring technology on fourteen free-ranging brown bears over three winters, we recorded movement, heart rate (HR), heart rate variability (HRV), body temperature (T(b)), physical activity, ambient temperature (T(A)), and snow depth to identify the drivers of the start and end of hibernation. …”
Publicado 2016
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73796por Zeh, Clement, Inzaule, Seth C., Ondoa, Pascale, Nafisa, Lillian G., Kasembeli, Alex, Otieno, Fredrick, Vandenhoudt, Hilde, Amornkul, Pauli N., Mills, Lisa A., Nkengasong, John N.“…OBJECTIVE: To identify unique characteristics of recent versus established HIV infections and describe sexual transmission networks, we characterized circulating HIV-1 strains from two randomly selected populations of ART-naïve participants in rural western Kenya. METHODS: Recent HIV infections were identified by the HIV-1 subtype B, E and D, immunoglobulin G capture immunoassay (IgG BED-CEIA) and BioRad avidity assays. …”
Publicado 2016
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73797por Ribeiro-Vaz, Inês, Silva, Ana-Marta, Costa Santos, Cristina, Cruz-Correia, Ricardo“…The aim of this work is to describe the state of the art information systems used to promote adverse drug reaction reporting. …”
Publicado 2016
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73798por Calderone, Alberto, Formenti, Matteo, Aprea, Federica, Papa, Michele, Alberghina, Lilia, Colangelo, Anna Maria, Bertolazzi, Paola“…RESULTS: In this work we propose a strategy that exploits network community structure identified with a state-of-the-art network community discovery algorithm called InfoMap, which takes advantage of information theory principles. …”
Publicado 2016
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73799“…The proposed method achieves better accuracy than the best state-of-the-art method both in terms of the geometric mean of the specificity and sensitivity and the area under the receiver operating characteristic and precision recall curves. …”
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73800por Schirmer, Melanie, D’Amore, Rosalinda, Ijaz, Umer Z., Hall, Neil, Quince, Christopher“…We evaluated the Genome Analyzer II, HiSeq and MiSeq and tested state-of-the-art low input library preparation methods. Analysing in vitro metagenomic sequencing data allowed us to determine biases directly associated with the actual sequencing process. …”
Publicado 2016
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