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  1. 73861
    por Cowman, Tyler, Koyutürk, Mehmet
    Publicado 2017
    “…Our results show that, as compared other state-of-the-art tools for fast epistasis detection, LinDen drastically reduces the number of tests performed while discovering statistically significant locus pairs. …”
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    Prioritizing tests of epistasis through hierarchical representation of genomic redundancies
  2. 73862
    por Budidha, K, Kyriacou, P A
    Publicado 2017
    “…A novel miniature ear canal PPG sensor was developed along with a state of the art PPG processing unit to investigate PPG measurements from the bottom surface of the ear canal. …”
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    In vivo investigation of ear canal pulse oximetry during hypothermia
  3. 73863
    “…BACKGROUND: Oocyte cryopreservation is an essential part of the assisted reproductive technology (ART), which was recently introduced into clinical practice. …”
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    Comparison of The Effects of Vitrification on Gene Expression of Mature Mouse Oocytes Using Cryotop and Open Pulled Straw
  4. 73864
    “…Data and results of the proposed method are contrasted with those reported in the state of the art. RESULTS: The webcam achieved better results in the performance analysis of video cameras. …”
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    Video pulse rate variability analysis in stationary and motion conditions
  5. 73865
    “…However, how to partition data in practical phylogenetic analysis, and in particular in relaxed-clock dating analysis, is more art than science. Here, we use computer simulation and real data analysis to study the impact of the partition scheme on divergence time estimation. …”
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    An Evaluation of Different Partitioning Strategies for Bayesian Estimation of Species Divergence Times
  6. 73866
    “…In addition, the metabolic profile of the fungal strains was unraveled using state-of-the-art LC-MS/MS instrumentation. The three gene-sequence data grouped the isolates into two major clades, A. minisclerotigenes and A. flavus. …”
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    Genetic and Toxigenic Variability within Aspergillus flavus Population Isolated from Maize in Two Diverse Environments in Kenya
  7. 73867
    “…This approach was presumed to be as effective as state of the art islet transplantation, aside from immunosuppression drawbacks. …”
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    Stem cells and beta cell replacement therapy: a prospective health technology assessment study
  8. 73868
    por Daberdaku, Sebastian, Ferrari, Carlo
    Publicado 2018
    “…The proposed method was validated on 16 classes of proteins extracted from the Protein–Protein Docking Benchmark 5.0 and compared to other state-of-the-art protein interface predictors (SPPIDER, PrISE and NPS-HomPPI). …”
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    Exploring the potential of 3D Zernike descriptors and SVM for protein–protein interface prediction
  9. 73869
    “…We conduct extensive experiments over OMIM datasets, and IDLP has demonstrated its effectiveness compared with eight state-of-the-art approaches. The robustness of IDLP is also validated by doing experiments with disturbed PPI network. …”
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    Prioritizing disease genes with an improved dual label propagation framework
  10. 73870
    “…This review summarizes the state-of-the-art of the complex kinase mTORC1 focusing in upstream and downstream pathways, their role in central nervous system and their relationship with autophagy, apoptosis and neuroprotection/neurodegeneration after ischemia/hypoxia.…”
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    Role of mTORC1 Controlling Proteostasis after Brain Ischemia
  11. 73871
    por Yang, Shu, Wang, Junwen, Ng, Raymond T.
    Publicado 2018
    “…Moreover, it shows comparable performance with two state-of-the-art methods that require the presence of the experimental binding data. …”
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    Inferring RNA sequence preferences for poorly studied RNA-binding proteins based on co-evolution
  12. 73872
    “…In comparison with existing clinical risk scoring methods and state-of-the-art machine learning methods, our method provides significant improvements in survival predictions, both post- and pre-cardiac transplantation. …”
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    Personalized survival predictions via Trees of Predictors: An application to cardiac transplantation
  13. 73873
    “…A test was introduced to monitor accuracy of the applied couch offset detection in the TomoTherapy Hi‐Art treatment system using the TQA “Step‐Wedge Helical” module and MVCT detector. …”
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    Statistical process control and verifying positional accuracy of a cobra motion couch using step‐wedge quality assurance tool
  14. 73874
    “…METHODS: We used the Cost‐Effectiveness of Preventing AIDS Complications (CEPAC)‐International model of HIV prevention and treatment to evaluate two strategies: the current standard of care (SOC) in Brazil, including universal ART access (No PrEP strategy); and the current SOC plus daily tenofovir/emtracitabine PrEP (PrEP strategy) until age 50. …”
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    The cost‐effectiveness of HIV pre‐exposure prophylaxis in men who have sex with men and transgender women at high risk of HIV infection in Brazil
  15. 73875
    “…INTRODUCTION: We sought to investigate associations of regional white matter hyperintensities (WMHs) within white matter (WM) tracts with cardiovascular risk and brain aging-related atrophy throughout adulthood in the general population, leveraging state of the art pattern analysis methods. METHODS: We analyzed a large sample (n = 2367) from the Study of Health in Pomerania, Germany (range 20–90 years). …”
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    Regional tract-specific white matter hyperintensities are associated with patterns of aging-related brain atrophy via vascular risk factors, but also independently
  16. 73876
    “…BACKGROUND: Advances in medical treatment for HIV are driving major changes in HIV policy and practice, including the encouragement of intake and adherence to HIV antiretroviral treatment (ART) by people living with HIV (PLHIV) for both personal and public health benefits. …”
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    Development and validation of PozQoL: a scale to assess quality of life of PLHIV
  17. 73877
    “…The current state-of-the-art medical care for AD comprises three simple principles: prevent the preventable, achieve early diagnosis, and manage the manageable symptoms. …”
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    The Role of Genetics in Advancing Precision Medicine for Alzheimer’s Disease—A Narrative Review
  18. 73878
    “…METHODS: A retrospective follow up study was conducted from September 1 to December 30, 2016 to assess the magnitude and factors associated with virological and immunological failure among 260 adults and adolescents highly active antiretroviral therapy users who started first line ART between January 1, 2008 to March 1, 2016. A standardized questionnaire was used to collect socio-demographic and clinical data. …”
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    Virological and immunological failure of HAART and associated risk factors among adults and adolescents in the Tigray region of Northern Ethiopia
  19. 73879
    “…Our results reveal that the proposed real-time algorithms perform nearly as accurately as the existing state-of-the-art offline techniques, while providing a significant degree of adaptivity, statistical robustness, and computational savings.…”
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    Real-Time Tracking of Selective Auditory Attention From M/EEG: A Bayesian Filtering Approach
  20. 73880
    “…Of these, 263,266 are not included by state-of-the-art PTR catalogs. The new methodology is mainly based on a hierarchical and systematic application of alignment-based sequence comparisons to identify and measure the polymorphism of TR. …”
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    A Census of Tandemly Repeated Polymorphic Loci in Genic Regions Through the Comparative Integration of Human Genome Assemblies
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