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73981por Alvarez-Carbonell, David, Ye, Fengchun, Ramanath, Nirmala, Garcia-Mesa, Yoelvis, Knapp, Pamela E., Hauser, Kurt F., Karn, Jonathan“…Despite effective antiretroviral therapy (ART), HIV-associated neurocognitive disorders (HAND) are found in nearly one-third of patients. …”
Publicado 2019
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73982“…This paper gives an overview of the state of art in the studies on the fabrication, structural characterization, physical properties, and functional applications of rare earth-doped perovskite manganite oxide nanostructures. …”
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73983“…The experimental results demonstrate that our unsupervised system extracts cross-sentence events quite well and outperforms all the state-of-the-art supervised systems when combined with existing methods for intra-sentence event extraction. …”
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73984por Amendola, Alessandra, Sberna, Giuseppe, Forbici, Federica, Abbate, Isabella, Lorenzini, Patrizia, Pinnetti, Carmela, Antinori, Andrea, Capobianchi, Maria Rosaria“…Interestingly, LTR-based viremia (sometimes exceeding 1,000 copies/mL) was observed in a small proportion (up to 1%) of patients under ART, considered for long time virologically suppressed on the basis of a single target (pol-based) assay. …”
Publicado 2020
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73985por Alteri, Alessandra, Corti, Laura, Cermisoni, Greta Chiara, Papaleo, Enrico, Viganò, Paola, Noventa, Marco“…BACKGROUND: The prolonged culture of embryos to the blastocyst stage represents an increasing procedure in Assisted Reproductive Technology (ART) laboratories. Generally, only blastocysts developing on Day 5 and Day 6 are considered suitable embryos for transfer, cryopreservation or biopsy while embryos developed at a slower rate after Day 6 are routinely discarded. …”
Publicado 2020
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73986por Rogers, Julia H., Jabateh, Lassana, Beste, Jason, Wagenaar, Bradley H., McBain, Ryan, Palazuelos, Daniel, Wickett, Eugene, Oswald, Catherine, Napier, Harriet G., Toomey-Garbo, Julia“…Results: TB treatment coverage increased from 7.7% pre-intervention to 43.2% (p < 0.001) post-intervention and lost to follow-up (LTFU) rates decreased from 9.5% to 2.1% (p = 0.003). ART treatment coverage increased 3.8 percentage points (p = 0.03), with patient retention improving 63.9% to 86.1% (p < 0.001); a 6.0 percentage point decrease in HIV LTFU was also observed (p = 0.21). …”
Publicado 2018
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73987por Li, Ye, Zhu, Feng-Lin, Zheng, Xing-Wen, Hu, Man-Li, Dong, Chen, Diao, Ying, Wang, You-Wei, Xie, Ke-Qiang, Hu, Zhong-Li“…BACKGROUND: Lotus (Nelumbo nucifera) is an aquatic plant with important agronomic, horticulture, art and religion values. It was the basal eudicot species occupying a critical phylogenetic position in flowering plants. …”
Publicado 2020
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73988por Matías-Florentino, Margarita, Chaillon, Antoine, Ávila-Ríos, Santiago, Mehta, Sanjay R, Paz-Juárez, Héctor E, Becerril-Rodríguez, Manuel A, del Arenal-Sánchez, Silvia J, Piñeirúa-Menéndez, Alicia, Ruiz, Verónica, Iracheta-Hernández, Patricia, Macías-González, Israel, Tena-Sánchez, Jehovani, Badial-Hernández, Florentino, González-Rodríguez, Andrea, Reyes-Terán, Gustavo“…PATIENTS AND METHODS: HIV pol sequences were obtained by next-generation sequencing from 2447 individuals before initiation of ART at the largest HIV clinic in Mexico City (April 2016 to June 2018). …”
Publicado 2020
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73989por Cocker, Alexander T. H., Shah, Nishel M., Raj, Inez, Dermont, Sarah, Khan, Waheed, Mandalia, Sundhiya, Imami, Nesrina, Johnson, Mark R.“…In this study we aimed to define pregnancy and gestation related changes to HIV-1-specific responses and T-cell phenotype in ART treated HIV-1 positive pregnant women. Eleven non-pregnant and 24 pregnant HIV-1 positive women were recruited, peripheral blood samples taken, fresh cells isolated, and compared using ELISpot assays and flow cytometry analysis. …”
Publicado 2020
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73990por Li, Gong-Hua, Dai, Shaoxing, Han, Feifei, Li, Wenxing, Huang, Jingfei, Xiao, Wenzhong“…BACKGROUND: Constraint-based metabolic modeling has been applied to understand metabolism related disease mechanisms, to predict potential new drug targets and anti-metabolites, and to identify biomarkers of complex diseases. Although the state-of-art modeling toolbox, COBRA 3.0, is powerful, it requires substantial computing time conducting flux balance analysis, knockout analysis, and Markov Chain Monte Carlo (MCMC) sampling, which may limit its application in large scale genome-wide analysis. …”
Publicado 2020
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73991por Shi, Manhong, He, Hongxin, Geng, Wanchen, Wu, Rongrong, Zhan, Chaoying, Jin, Yanwen, Zhu, Fei, Ren, Shumin, Shen, Bairong“…Compared with several state-of-the-art methods, the proposed scheme firstly predicted subjects at risk of SCD up to 14 min earlier with an accuracy of 96.1%, a sensitivity of 97.5%, and a specificity of 94.4% 14 min before SCD onset. …”
Publicado 2020
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73992“…CONCLUSION: ABC and AZT based ART regimens seem to have comparable survival benefit among HIV-infected children in Ethiopia. …”
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73993“…Likewise, distinctive metabolic dysfunction has been named a leading cause and a hallmark of Alzheimer’s disease that is apparent decades prior to disease manifestation. State-of-the-art metabolomics studies demonstrate that altered branched-chain amino acids (BCAAs) metabolism accompanies Alzheimer’s disease development. …”
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73994“…Multi‐electrode arrays (MEAs) are a state‐of‐the‐art electrophysiological tool enabling the electrical activity of many cells to be recorded across multiple electrode sites (channels) simultaneously. …”
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73995por Ward-Caviness, Cavin K., Pu, Shirley, Martin, Chantel L., Galea, Sandro, Uddin, Monica, Wildman, Derek E., Koenen, Karestan, Aiello, Allison E.“…This principal component (PC7) was most strongly driven by the presence of abandoned cars, poor streets, and non-art graffiti. Models including both PC7 and individual indicators of neighborhood perception indicated that only PC7 and not neighborhood perception impacted the eMRS. …”
Publicado 2020
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73996“…CDK1 and CCNB1 were revealed to regulate proliferation and differentiation through the cell cycle and viral tumorigenesis, while FN1 and ITGB1, which may be developed as novel prognostic factors, were co-expressed to induce metastasis via cancer-associated signaling pathways, including PI3K-Art signaling pathway, and focal adhesion in CC; however, the underlying molecular mechanisms require further research.…”
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73997por Palmer, Matthew D.“…RECENT FINDINGS: State-of-the-art climate model simulations suggest that the global ocean becomes the dominant term the planetary heat budget on annual and longer timescales. …”
Publicado 2017
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73998por Mchunu, Nobuhle N., Mwambi, Henry G., Reddy, Tarylee, Yende-Zuma, Nonhlanhla, Naidoo, Kogieleum“…METHODS: We studied 4014 patients from the Centre for the AIDS Programme of Research in South Africa (CAPRISA) who initiated ART between June 2004 and August 2013. We used proportional hazards regression model to assess the effect of baseline characteristics (excluding CD4 count) on mortality, and linear mixed effect models to evaluate the effect of baseline characteristics on the CD4 count evolution over time. …”
Publicado 2020
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73999por De Roeck, Joris, Van Houcke, J., Almeida, D., Galibarov, P., De Roeck, L., Audenaert, Emmanuel A.“…Spatial marker trajectories and ground reaction force registrations are imported into the Anybody Modeling System based on subject-specific geometry and the state-of-the-art TLEM 2.0 dataset. Hip and knee joint reaction forces were obtained by a simulation with an inverse dynamics approach. …”
Publicado 2020
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74000por Alebel, Animut, Kibret, Getiye Dejenu, Petrucka, Pammla, Tesema, Cheru, Moges, Nurilign Abebe, Wagnew, Fasil, Asmare, Getnet, Kumera, Gemechu, Bitew, Zebenay Workneh, Ketema, Daniel Bekele, Tiruneh, Tesfahun, Melkamu, Mamaru Wubale, Hibstie, Yitbarek Tenaw, Temesgen, Belisty, Eshetie, Setegn“…Based on our findings, we suggested that all HIV-positive adults should be assessed for nutritional status at the time of ART commencement.…”
Publicado 2020
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