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74141“…It reviews available evidence regarding management of labor pain in obstetric patients with COVID-19, serious adverse events in obstetric anesthesia to help inform risk/benefit decisions, and increasingly popular neuraxial labor analgesia techniques and adjuvants. State-of-the-art modes of epidural drug delivery are also discussed. …”
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74142por Bashar, Syed Khairul, Ding, Eric Y., Walkey, Allan J., McManus, David D., Chon, Ki H.“…Our algorithm outperformed a state-of-the-art method for predicting AF in ICU patients, further demonstrating the efficacy of our proposed method. …”
Publicado 2021
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74143por Nazir, Tahira, Nawaz, Marriam, Rashid, Junaid, Mahum, Rabbia, Masood, Momina, Mehmood, Awais, Ali, Farooq, Kim, Jungeun, Kwon, Hyuk-Yoon, Hussain, Amir“…Both qualitative and quantitative results demonstrate that our proposed approach outperforms state-of-the-art methods due to more effective localization power of CenterNet, as it can easily recognize small lesions and deal with over-fitted training data. …”
Publicado 2021
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74144por Garnica, Oscar, Gómez, Diego, Ramos, Víctor, Hidalgo, J. Ignacio, Ruiz-Giardín, José M.“…The models obtain predictions that, for the best case, are up to a state-of-the-art accuracy of 85.9%, a sensitivity of 87.4% and an AUC of 0.93. …”
Publicado 2021
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74145por Ben-Ari, Tal, Chodick, Gabriel, Shalev, Varda, Goldstein, Dalit, Gomez, Roy, Landau, Zohar“…Objective: To assess a decade of growth hormone (GH) treatment patterns and outcomes in a real-world setting in Israel using a state-of-the-art computerized database. Methods: This large retrospective database study included 2,379 children initiating GH treatment in Maccabi Healthcare Services (between January 2004 and December 2014). …”
Publicado 2021
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74146por de Oliveira, Victor Moreira, da Rocha, Matheus Nunes, Magalhães, Emanuel Paula, da Silva Mendes, Francisco Rogênio, Marinho, Márcia Machado, de Menezes, Ramon Róseo Paula Pessoa Bezerra, Sampaio, Tiago Lima, dos Santos, Hélcio Silva, Martins, Alice Maria Costa, Marinho, Emmanuel Silva“…This work aims to perform a screening of pharmacodynamics and pharmacokinetics of synthetic hybrids from thymoquinone and artemisin (THY-ART) against COVID-19. RESULTS: Molecular docking studies indicated that hybrids of artemisinin and thymoquinone showed a relevant interaction with the active fraction of the enzyme Mpro, when compared to the reference drugs. …”
Publicado 2021
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74147por Perkhofer, Lukas, Golan, Talia, Cuyle, Pieter-Jan, Matysiak-Budnik, Tamara, Van Laethem, Jean-Luc, Macarulla, Teresa, Cauchin, Estelle, Kleger, Alexander, Beutel, Alica K., Gout, Johann, Stenzinger, Albrecht, Van Cutsem, Eric, Bellmunt, Joaquim, Hammel, Pascal, O’Reilly, Eileen M., Seufferlein, Thomas“…The data-driven consensus recommendations of the ESDO expert panel aim to provide clinicians guidance for a state-of-the-art management. ABSTRACT: Impaired DNA damage repair (DDR) is increasingly recognised as a hallmark in pancreatic ductal adenocarcinoma (PDAC). …”
Publicado 2021
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74148por Hamming-Vrieze, Olga, van Kranen, Simon, Walraven, Iris, Navran, Arash, Al-Mamgani, Abrahim, Tesselaar, Margot, van den Brekel, Michiel, Sonke, Jan-Jakob“…Clinical prediction based on patient characteristics or CBCT is challenging and dosimetric selection tools seem warranted to identify patients in need for ART, especially in treatment with small PTV margins.…”
Publicado 2021
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74149por Jin, Yongmei, Assanangkornchai, Sawitri, Fang, Meiqin, Guan, Wei, Tian, Bo, Yu, Min, Du, Yingrong“…RESULTS: A total of 702 participants living with HIV aged ≥ 18 years (median age: 41.0 years, 69.4% male) who had been on ART for 1–5 years were recruited. Based on ordinal logistic regression modeling, predisposing factors: being employed (adjusted odds ratio (AOR): 1.54, 95% confidence interval (CI): 1.13–2.11), heterosexuals (AOR: 1.58, 95% CI: 1.11–2.25) and men who have sex with men (AOR: 2.05, 95% CI: 1.39–3.02) and enabling factors: Urban Employee Basic Medical Insurance (AOR: 1.90, 95% CI: 1.03–3.54), middle socioeconomic status (SES) (AOR: 1.42, 95% CI: 1.01–2.01), were positively associated with the higher level of continuous care uptake, compared to the unemployed, people who inject drugs, those with no medical insurance and low SES, respectively. …”
Publicado 2021
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74150“…The objective of this study was to integrate logic rules with state-of-the-art natural language processing (NLP) and machine learning technologies to detect substance use information from both structured and unstructured EHR data. …”
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74151“…RESULTS: We implement motif_prob in both Perl and C+ + languages, using an efficient error-bound iterative process for the exact formula, providing comparison with state-of-the-art tools (e.g. MoSDi) in terms of precision, run time benchmarks, along with a real-world use case on bacterial motif characterization. …”
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74152por Biskup, Ewelina, Xin, Zhaochen, Li, Rui, Zucal, John P., Lu, Yao, Sun, Yun, Appiah, Leslie Coker, Lindheim, Steven R., Zhang, Hongwei“…Background: As cancer has become a major public health issue in China, fertility preservation remains limited despite the wide application of Assisted Reproductive Technology (ART) throughout the country. Objective: This study aimed to identify gaps in knowledge and communication as well as referrals in the previous year regarding oncofertility among medical and surgical oncologists and breast cancer patients (BCPs) in Chinese academic settings to target areas of needed improvement. …”
Publicado 2021
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74153por Kobayashi, Mariya, Nakagawa, Satoshi, Kawanishi, Yoko, Masuda, Tatsuo, Maenaka, Takahide, Toda, Aska, Miyake, Tatsuya, Hiramatsu, Kosuke, Miyoshi, Ai, Mimura, Kazuya, Kimura, Toshihiro, Endo, Masayuki, Kimura, Tadashi“…We found significant differences between requirements for invasive versus non-invasive strategies according to gestational age at delivery, assisted reproductive technology (ART) pregnancy, amount of blood loss at delivery, and the long axis of the RPOC-ARC lesion (p = 0.028, p = 0.009, p = 0.004, and p = 0.002, respectively). …”
Publicado 2021
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74154por Rood, Kristiana, Begum, Khodeza, Wang, Hanmin, Wangworawat, Yan C., Davis, Ryan, Yamauchi, Celina R., Perez, Mia C., Simental, Alfred A., Laxa, Ria T., Wang, Charles, Roy, Sourav, Khan, Salma“…We determined the differential expressions of microRNA in archival samples from Filipino Americans compared to European Americans using the state-of-the-art technique, HiSeq4000. By ingenuity pathway analysis, we determined miRNA targets and the pathways that those targets are involved in. …”
Publicado 2021
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74155por Dantas da Silva Júnior, José Roberto, Pedruzzi, Rizzieri, de Souza, Filipe Milani, Ferraz, Patrick Silva, Silva, Daniel Guimarães, Vieira, Carolina Sacramento, de Moraes, Marcelo Romero, Nascimento, Erick Giovani Sperandio, Moreira, Davidson Martins“…The main model of this type, WRF-Hydro Weather Research and Forecasting Model), represents the state of the art regarding water resources, as well as being the object of study of small and medium-sized river basins that tend to have less water availability. hydrometeorological data and analysis. …”
Publicado 2021
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74156por Nallappan, Devi, Fauzi, Agustine Nengsih, Krishna, Balam Satheesh, Kumar, Basivi Praveen, Reddy, Avula Vijaya Kumar, Syed, Tasqeeruddin, Reddy, Cirandur Suresh, Yaacob, Nik Soriani, Rao, Pasupuleti Visweswara“…Studies on green biosynthesis of newly engineered nanoparticles for their prominent medicinal applications are being the torch-bearing concerns of the state-of-the-art research strategies. In this concern, we have engineered the biosynthesized Luffa acutangula silver nanoparticles of flavonoid O-glycosides in the anisotropic form isolated from aqueous leave extracts of Luffa acutangula, a popular traditional and ayurvedic plant in south-east Asian countries. …”
Publicado 2021
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74157“…Phirbo was evaluated on three benchmark sets of known virus–host pairs, and it improved precision and recall by 11–40 percentage points over currently available, state-of-the-art, alignment-based, alignment-free, and machine-learning host prediction tools. …”
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74158“…Embryo cryopreservation is a widely used technique in infertility management and today is an essential part of assisted reproductive technology (ART). In some cases, re-vitrification can be applied to good quality supernumerary warmed embryos that have not been transferred in the present cycle. …”
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74159por Aparicio-Esteve, Elena, Ureña, Jesús, Hernández, Álvaro, Pizarro, Daniel, Moltó, David“…This work investigates the use of different state-of-the-art PnP algorithms to localize the receiver in a large space of 2 × 2 m [Formula: see text] based on four co-planar transmitters and with a distance from transmitters to receiver up to [Formula: see text] m. …”
Publicado 2021
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74160por Sharma, Bikramjit, Tran, Van Anh, Pongratz, Tim, Galazzo, Laura, Zhurko, Irina, Bordignon, Enrica, Kast, Stefan M., Neese, Frank, Marx, Dominik“…[Image: see text] The isotropic hyperfine coupling constant (HFCC, A(iso)) of a pH-sensitive spin probe in a solution, HMI (2,2,3,4,5,5-hexamethylimidazolidin-1-oxyl, C(9)H(19)N(2)O) in water, is computed using an ensemble of state-of-the-art computational techniques and is gauged against X-band continuous wave electron paramagnetic resonance (EPR) measurement spectra at room temperature. …”
Publicado 2021
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