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  1. 74921
    “…Those with GSTM1 coding for the functional antioxidant enzyme Glutathione S-transferase (GST), had higher CD4 cell count (β=3.48, p=0.034), lower HIV viral load (β=−0.536, p=0.018), and lower mitochondrial 8-oxo-dG (β=−0.28, p=0.03). ART reduced oxidative stress in the participants with the GSTM1 coding for the functional antioxidant enzyme. …”
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    Effect of GSTM1-Polymorphism on Disease Progression and Oxidative Stress in HIV Infection: Modulation by HIV/HCV Co-Infection and Alcohol Consumption
  2. 74922
    por Sprague, Courtenay, Simon, Sara E
    Publicado 2014
    “…Stark health system drop out occurred immediately after receipt of HIV test results, with ART initiation generally occurring when individuals became ill. …”
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    Understanding HIV care delays in the US South and the role of the social-level in HIV care engagement/retention: a qualitative study
  3. 74923
    “…We compared development of various forms of renal impairment with use of TDF-containing antiretroviral therapy (ART) between a cohort from the Institute of Infectious Diseases (IID) Pune, Western India and the Royal Free Hospital (RFH) London, UK. …”
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    Higher risk of renal impairment associated with tenofovir use amongst people living with HIV in India: A comparative cohort analysis between Western India and United Kingdom
  4. 74924
    “…CONCLUSIONS: The application of the Characteristic Direction method may shed new light on relevant biological mechanisms that would have remained undiscovered by the current state-of-the-art DEG methods. The method is freely accessible via various open source code implementations using four popular programming languages: R, Python, MATLAB and Mathematica, all available at: http://www.maayanlab.net/CD.…”
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    The characteristic direction: a geometrical approach to identify differentially expressed genes
  5. 74925
    “…Our ontologies outperform existing state-of-the-art gene regulation ontologies in the automatic rule learning method applied to our corpus. …”
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    Extracting rate changes in transcriptional regulation from MEDLINE abstracts
  6. 74926
    “…BACKGROUND: Some aspects of HIV-related stigma have been shown to be a barrier to HIV services uptake and adherence to antiretroviral treatment (ART). Distinguishing which domains of stigma impact HIV services uptake can enhance the efficacy and efficiency of stigma-reduction interventions. …”
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    Community stigma endorsement and voluntary counseling and testing behavior and attitudes among female heads of household in Zambézia Province, Mozambique
  7. 74927
    “…Extending the capability and improving the accessibility of existing simulation packages the software goes beyond the state of the art in the domain of biomolecular simulations. Thus we expect that it will stimulate more individuals from the community to employ more confidently modeling in their research. …”
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    Native structure-based modeling and simulation of biomolecular systems per mouse click
  8. 74928
    “…Afterwards, all the knowledge and skills students acquired must be integrated into complete consultations, an art that lies at the heart of the medical profession. …”
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    Managing the complexity of doing it all: an exploratory study on students’ experiences when trained stepwise in conducting consultations
  9. 74929
    “…This is combined with computed tomography (CT) and both performed with a four dimensional (4D) technique that tracks respiratory motion. This state-of-the-art scan has superior resolution, accuracy and quantitative ability than previous techniques. …”
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    A prospective observational study of Gallium-68 ventilation and perfusion PET/CT during and after radiotherapy in patients with non-small cell lung cancer
  10. 74930
    “…We present here a secondary analysis comparing markers in those receiving abacavir- vs tenofovir- based antiretroviral therapy (ART). MATERIALS AND METHODS: This cross-sectional study included 101 HIV-1 infected individuals stable (HIV RNA<50 cps/ml, >6 months) on antiretroviral regimens including tenofovir (TDF)/emtricitabine or abacavir/lamivudine plus a ritonavir boosted PI. …”
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    Impact of NRTI backbone on renal, bone and cardiovascular markers in HIV-infected individuals receiving a boosted protease inhibitor
  11. 74931
    “…BACKGROUND: We evaluated predictors and outcomes of Mycobacterium tuberculosis bacteremia among participants undergoing baseline mycobacterial blood culture in the ACTG A5221 STRIDE study, a randomized clinical trial comparing earlier with later ART among HIV-infected patients suspected of having tuberculosis with CD4-positive T-lymphocyte counts (CD4 counts) <250 cells/mm(3). …”
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    Predictors and outcomes of Mycobacterium tuberculosis bacteremia among patients with HIV and tuberculosis co-infection enrolled in the ACTG A5221 STRIDE study
  12. 74932
    por Haroske, Gunter, Schrader, Thomas
    Publicado 2014
    “…The generic terms were mapped to SNOMED-CT terms using "ArtDecor". RESULTS: The 488 PathLex element templates for Anatomic Pathology (AP) observations can be reduced to 53 generic templates, leaving out only 17 templates very specific for organ and/or disease. …”
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    A reference model based interface terminology for generic observations in Anatomic Pathology Structured Reports
  13. 74933
    “…METHODS: We evaluated 288 HIV/HCV-coinfected cohort participants with undetectable HIV RNA (< 50 HIV-1 RNA copies/mL) on two consecutive visits while on combination antiretroviral therapy (cART) without fibrosis [aspartate aminotransferase to platelet ratio index (APRI) < 1.5], end-stage liver disease or HCV therapy. …”
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    HIV virological rebounds but not blips predict liver fibrosis progression in antiretroviral-treated HIV/hepatitis C virus-coinfected patients
  14. 74934
    “…BACKGROUND: Whereas 40 % to 70 % of papillary thyroid carcinomas (PTCs) are characterized by a BRAF mutation (BRAF(mut)), unified biomarkers for the genetically heterogeneous group of BRAF wild type (BRAF(wt)) PTCs are not established yet. Using state-of-the-art technology we compared RNA expression profiles between conventional BRAF(wt) and BRAF(mut) PTCs. …”
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    Effect of BRAF mutational status on expression profiles in conventional papillary thyroid carcinomas
  15. 74935
    “…OBJECTIVE: To evaluate the evidence on the efficacy of psychosocial interventions for improving pregnancy rates and reducing distress for couples in treatment with assisted reproductive technology (ART). DESIGN: Systematic review and meta-analysis. …”
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    Efficacy of psychosocial interventions for psychological and pregnancy outcomes in infertile women and men: a systematic review and meta-analysis
  16. 74936
    “…Community-based campaigns, such as the IPC, may be able to assist countries to achieve earlier testing and initiation of ART in the course of HIV infection. Improving referral mechanisms and strengthening linkages between HIV testing and treatment services remain a challenge and electronic medical record (EMR) systems may support monitoring of patients throughout the HIV care and treatment continuum.…”
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    Stage of HIV presentation at initial clinic visit following a community-based HIV testing campaign in rural Kenya
  17. 74937
    “…Among HIV-infected individuals with available data, 41% of 2629 were receiving antiretroviral therapy (ART). The annual SARI hospitalisation incidence ranged from 325-617/100,000 population. …”
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    Epidemiology of Severe Acute Respiratory Illness (SARI) among Adults and Children Aged ≥5 Years in a High HIV-Prevalence Setting, 2009–2012
  18. 74938
    “…The mean duration of HIV infection and ART treatment were 6 years (SD = 3.6) and 5 years (SD = 2.2), respectively. …”
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    Motivation to quit smoking among HIV-positive smokers in Vietnam
  19. 74939
    por Köhl, Karin, Gremmels, Jürgen
    Publicado 2015
    “…Efficient statistical evaluation of phenotyping data requires standardised data storage ensuring long-term data availability while maintaining intellectual property rights. This is state of the art at phenomics centres, which, however, are unavailable for most scientists. …”
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    A software tool for the input and management of phenotypic data using personal digital assistants and other mobile devices
  20. 74940
    “…GWAS have become a state-of-the-art approach to genetically improve economically important traits. …”
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    Genome-wide association studies (GWAS) identify a QTL close to PRKAG3 affecting meat pH and colour in crossbred commercial pigs
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