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  1. 75121
    “…CONCLUSION: Tubular dysfunction was uncommon in Zimbabwean children on a TDF-based ART regimen. Hypophosphatemia, proteinuria and reduction in eGFR were common. …”
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    Proximal renal tubular function in HIV-infected children on tenofovir disoproxil fumarate for treatment of HIV infection at two tertiary hospitals in Harare, Zimbabwe
  2. 75122
    “…We compare HAPLEXR and HAPLEXD with three state-of-the-art expression prediction methods and two novel logistic regression approaches across five GTEx v8 tissues. …”
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    Combinatorial and statistical prediction of gene expression from haplotype sequence
  3. 75123
    “…Numerical results indicate that, compared to state-of-the-art graph embedding methods, hierarchical variational graph auto-encoder learns more informative and generalizable disease representations. …”
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    Network-principled deep generative models for designing drug combinations as graph sets
  4. 75124
    “…METHODS: Between January and August 2018, a consecutive series of female participants from the Population-Cohort of the previous HIV prevention trial HPTN 071 (PopART), resident in Livingstone, Zambia were invited to take part in BILHIV if they were 18–31 years old, non-pregnant and sexually active. …”
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    Genital self-sampling compared with cervicovaginal lavage for the diagnosis of female genital schistosomiasis in Zambian women: The BILHIV study
  5. 75125
    “…METHODS: This protocol focuses on the second phase of a larger study of multimodal signal acquisition through facial muscle electrical activity, cardiac electrical activity, and electrodermal activity as indicators of pain and for building predictive models. We used state-of-the-art standard sensors to measure bioelectrical electromyographic signals and changes in heart rate, respiratory rate, and oxygen saturation. …”
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    Prospective Study Evaluating a Pain Assessment Tool in a Postoperative Environment: Protocol for Algorithm Testing and Enhancement
  6. 75126
    “…Prevention programs including screening, state-of-the-art diagnostic modalities and therapeutic approaches to CRC are being constantly improved. …”
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    Role of 18F-FDG PET/CT in the Follow-up of Colorectal Cancer
  7. 75127
    “…To this purpose, Per2 expression in circulating HPC was compared in 69 chronic HIV infected patients under successful ART and in matched 30 uninfected healthy donors (HD). …”
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    Per2 Upregulation in Circulating Hematopoietic Progenitor Cells During Chronic HIV Infection
  8. 75128
    “…We assembled this into a unified T3SE prediction pipeline, T3SEpp, which integrated the results of individual modules, resulting in high accuracy (i.e., ∼0.94) and >1-fold reduction in the false-positive rate compared to that of state-of-the-art software tools. The T3SEpp pipeline and sequence features observed here will facilitate the accurate identification of new T3SEs, with numerous benefits for future studies on host-pathogen interactions. …”
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    T3SEpp: an Integrated Prediction Pipeline for Bacterial Type III Secreted Effectors
  9. 75129
    “…This paper therefore presents candidate shape optimisation methods which might benefit the prosthetist and the limb user, by blending the state of the art from prosthetic mechanical design, surrogate modelling and evolutionary computation. …”
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    Predictive prosthetic socket design: part 2—generating person-specific candidate designs using multi-objective genetic algorithms
  10. 75130
    “…This study aims to investigate performance of non-invasive state-of-the-art and novel T-wave markers for repolarization dispersion in an ex vivo model. …”
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    Body Surface Mapping of Ventricular Repolarization Heterogeneity: An Ex-vivo Multiparameter Study
  11. 75131
    “…Initial assessments indicate that it has state-of-the-art performance and is readily extensible upon further benchmarking on larger data sets.…”
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    Occupation Coding of Job Titles: Iterative Development of an Automated Coding Algorithm for the Canadian National Occupation Classification (ACA-NOC)
  12. 75132
    “…METHOD: In this study, we were able to collect process data on the most commonly used high-value gold scrap recycling process, the aqua regia method, from several state-of-the-art German refineries. With this data, life cycle inventories were created and a life cycle model was produced to finally generate life cycle impacts of high-value gold scrap recycling. …”
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    Environmental impact of high-value gold scrap recycling
  13. 75133
    por Schreiner, Sonja
    Publicado 2020
    “…He completed the philosophicum (artisterium), studying the septem artes liberales (1835–1837) in Pest, comprising humanities and natural science. …”
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    Ignaz Semmelweis: a victim of harassment?
  14. 75134
    “…Through real-time qRT-PCR we extended the analysis of a miRNA subset and further investigated miR-320a role through state-of-the-art techniques. We identified 16 upregulated and 32 downregulated miRNAs in MPMs versus normal tissue, including the previously identified potential biomarkers miR-21, miR-126, miR-143, miR-145. …”
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    P53-regulated miR-320a targets PDL1 and is downregulated in malignant mesothelioma
  15. 75135
    “…Following hospital admission predefined in- and exclusion criteria for eCPR were checked; in the remaining 224, 126 were considered as eligible for eCPR. State of the art postresuscitation therapy was applied and prognostication of neurological outcome was performed according to a standardized protocol. …”
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    Establishment of an extracorporeal cardio-pulmonary resuscitation program in Berlin – outcomes of 254 patients with refractory circulatory arrest
  16. 75136
    “…CONCLUSIONS: This work furthers the state of the art by modeling pertinent biomarker responses to tcVNS. …”
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    Digital Cardiovascular Biomarker Responses to Transcutaneous Cervical Vagus Nerve Stimulation: State-Space Modeling, Prediction, and Simulation
  17. 75137
    “…RESULTS: Across waves, a majority (81%) of the items consistently demonstrated moderate to high agreement except for items such as public/communal space, amount of shade, sidewalk features, number of traffic lanes, garden/flower bed/planter, art/statue/monument, amount of trash, and physical disorder. …”
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    An audit tool for longitudinal assessment of the health-related characteristics of urban neighborhoods: implementation methods and reliability results
  18. 75138
    “…The present review summarizes the state of the art for genetic variation as a predictive biomarker for cGvHD. …”
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    Review of Genetic Variation as a Predictive Biomarker for Chronic Graft-Versus-Host-Disease After Allogeneic Stem Cell Transplantation
  19. 75139
    “…We considered two state-of-the-art diffusion datasets, including single-diffusion-encoding (SDE) spin-echo data from a human brain with over 3820 unique diffusion weightings (the MASSIVE dataset), and double (oscillating) diffusion encoding data (DDE/DODE) of a mouse brain including over 2520 unique data points. …”
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    On the generalizability of diffusion MRI signal representations across acquisition parameters, sequences and tissue types: Chronicles of the MEMENTO challenge
  20. 75140
    “…Another way is to leverage state-of-the-art methods for multi-omics data integration. In this paper, we developed Drug Response analysis Integrating Multi-omics and time-series data (DRIM), an integrative multi-omics and time-series data analysis framework that identifies perturbed sub-pathways and regulation mechanisms upon drug treatment. …”
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    DRIM: A Web-Based System for Investigating Drug Response at the Molecular Level by Condition-Specific Multi-Omics Data Integration
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