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  1. 75401
    “…Reducing the barriers to processing and sharing high-quality human motion biomechanics data will enable more people to use state-of-the-art biomechanical analysis, do so at lower cost, and share larger and more accurate datasets.…”
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    AddBiomechanics: Automating model scaling, inverse kinematics, and inverse dynamics from human motion data through sequential optimization
  2. 75402
    “…CONCLUSION: Our final system for contact map prediction achieves state-of-the-art performances, and may provide valuable constraints for improved ab initio prediction of protein structures. …”
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    A two-stage approach for improved prediction of residue contact maps
  3. 75403
    “…BACKGROUND: Anthroposophic therapies (counselling, special medication, art, eurythmy movement, and rhythmical massage) aim to stimulate long-term self-healing processes, which theoretically could lead to a reduction of healthcare use. …”
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    Health costs in anthroposophic therapy users: a two-year prospective cohort study
  4. 75404
    “…METHODS: Prospective (n = 36) and retrospective (n = 21) clinical specimens from various anatomical sites were analyzed for the presence of herpes simplex virus 1 or 2 by real-time PCR using the RealArt HSV 1/2 LC PCR Kit. Specimens were analyzed by PCR both before and following automated nucleic acid extraction. …”
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    Real-Time PCR for detection of herpes simplex virus without nucleic acid extraction
  5. 75405
    “…CONCLUSION: The SMM-align method was shown to outperform other state of the art MHC class II prediction methods. The method predicts quantitative peptide:MHC binding affinity values, making it ideally suited for rational epitope discovery. …”
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    Prediction of MHC class II binding affinity using SMM-align, a novel stabilization matrix alignment method
  6. 75406
    “…In particular, the best tree obtained based on the new matrix of amino acid replacement (MtPan) was preferred over those obtained using previously available matrices (MtArt and MtRev) because of its higher likelihood score. …”
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    Phylogenetic analysis of mitochondrial protein coding genes confirms the reciprocal paraphyly of Hexapoda and Crustacea
  7. 75407
    por Brameier, Markus, Wiuf, Carsten
    Publicado 2007
    “…CONCLUSION: Our motif finding method is at least competitive to state-of-the-art feature-based methods for ab initio miRNA discovery. …”
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    Ab initio identification of human microRNAs based on structure motifs
  8. 75408
    “…CONCLUSION: TMpro uses very few free parameters in modeling TM segments as opposed to the very large number of free parameters used in state-of-the-art membrane prediction methods, yet achieves very high segment accuracies. …”
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    Transmembrane helix prediction using amino acid property features and latent semantic analysis
  9. 75409
    “…This broad range of functions is achieved through specific structures that have been (presumably) optimized through evolution. State-of-the-art methods, such as McCaskill's algorithm, use a statistical mechanics framework based on the computation of the partition function over the canonical ensemble of all possible secondary structures on a given sequence. …”
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    Efficient Algorithms for Probing the RNA Mutation Landscape
  10. 75410
    “…This analysis applies state-of-the art statistical methods such as the bootstrap and permutation tests to a medical problem of topical interest. …”
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    Using ordinal logistic regression to evaluate the performance of laser-Doppler predictions of burn-healing time
  11. 75411
    “…The final predictors are state-of-the-art, with a template-less prediction boundary recall of 50.8% (precision 38.7%) within ± 20 residues and a single domain recall of 80.3% (precision 78.1%). …”
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    Ab initio and homology based prediction of protein domains by recursive neural networks
  12. 75412
    “…Evaluation of these data sets shows that they are reasonable representations of the spectrum of proteins obtained from cellular proteomic studies. Six state-of-the-art predictors have been used to test the usefulness of the construction algorithm that we proposed. …”
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    Representative transcript sets for evaluating a translational initiation sites predictor
  13. 75413
    “…The enormous oxygen demand is generated in an air-separation unit by a cryogenic process, which is the only available state-of-the-art technology. The generation of oxygen and the purification and liquefaction of the CO(2)-enriched flue gas consumes significant auxiliary power. …”
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    The oxycoal process with cryogenic oxygen supply
  14. 75414
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    Biologic predictors of extension of oligoarticular juvenile idiopathic arthritis as determined from synovial fluid cellular composition and gene expression
  15. 75415
    “…For outcome analyses, the study will use state of the art latent growth curve modelling techniques, including all randomized participants according to the intention-to-treat principle. …”
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    INCANT: a transnational randomized trial of Multidimensional Family Therapy versus treatment as usual for adolescents with cannabis use disorder
  16. 75416
    “…In addition, we also demonstrate the predictive power of our proposed method by modelling two protein complexes: the calmodulin/myosin light chain kinase complex and the heat shock locus gene products U and V complex, which indicate that our method can identify more hot spots in these two complexes compared with other state-of-the-art methods. CONCLUSION: We have developed an accurate prediction model for hot spot residues, given the structure of a protein complex. …”
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    APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
  17. 75417
    “…The majority of patients in both groups were treated successfully within the first year after ART-initiation (susceptible: 89.9%; 62/69; resistant: 7/9; 77.8%). …”
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    Prevalence of Transmitted Drug Resistance and Impact of Transmitted Resistance on Treatment Success in the German HIV-1 Seroconverter Cohort
  18. 75418
    por Giancarlo, Raffaele, Utro, Filippo
    Publicado 2011
    “…Although NMF is an increasingly popular technique for biological data mining, our results are somewhat disappointing and complement quite well the state of the art about NMF, shedding further light on its merits and limitations. …”
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    Speeding up the Consensus Clustering methodology for microarray data analysis
  19. 75419
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    Clinical Presentation and Pathogenesis of Cold-Induced Autoinflammatory Disease in a Family With Recurrence of an NLRP12 Mutation
  20. 75420
    “…RESULTS: In this paper, we introduce a new Viral Spectrum Assembler (ViSpA) method for quasispecies spectrum reconstruction and compare it with the state-of-the-art ShoRAH tool on both simulated and real 454 pyrosequencing shotgun reads from HCV and HIV quasispecies. …”
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    Inferring viral quasispecies spectra from 454 pyrosequencing reads
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