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75421“…Our experiments suggest that NPS-HomPPI is competitive with several state-of-the-art interface prediction servers including those that exploit the structure of the query proteins. …”
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75422“…We first evaluated the effectiveness of netSVM using simulation studies, demonstrating its improved performance over state-of-the-art network-based methods and gene-based methods for network biomarker identification. …”
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75423por Mirkuzie, Alemnesh H, Hinderaker, Sven Gudmund, Sisay, Mitike Molla, Moland, Karen Marie, Mørkve, Odd“…RESULTS: Of 282 mothers enrolled in the cohort, 232 (82%, 95% CI 77-86%) initiated medication during pregnancy, 154 (64%) initiated combined zidovudine (ZDV) prophylaxis regimen while 78 (33%) were initiated lifelong antiretroviral treatment (ART). In total, 171 (60%, 95% CI 55-66%) mothers ingested medication during labour. …”
Publicado 2011
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75424“…When compared with the state-of-the-art prediction models in the independent test, our method demonstrates comparable or better performance. …”
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75425por van de Ven, Geertje, Draskovic, Irena, Adang, Eddy MM, Donders, Rogier ART, Post, Aukje, Zuidema, Sytse U, Koopmans, Raymond TCM, Vernooij-Dassen, Myrra JFJEnlace del recurso
Publicado 2012
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75426por Kantheti, Lalith Prakash Chandra, Reddy, BVR, Ravikumar, Shamala, Anuradha, CH, Chandrasekhar, P, Rajeswari, M Raja“…AIMS AND OBJECTIVES: To know the prevalence of Candidal colonization, and to isolate and know the Candidal species prevalent in the oral cavity from the oral rinse samples collected from the individuals attending to the Voluntary Counseling and Confidential Testing Center (VCCTC) and the antiretro-viral therapy (ART) Center at Government General Hospital, Guntur, Andhra Pradesh, South India. …”
Publicado 2012
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75427por Obermeier, M, Ingiliz, P, Weitner, L, Cordes, C, Moll, A, Hintsche, B, Schlote, F, Koeppe, S, Christensen, S, Mayr, C, Baumgarten, A“…In the multivariate analysis, ART at diagnosis, HCV RNA drop at week 12, hemoglobin levels and higher platelets were associated with SVR. …”
Publicado 2011
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75428por Pyysalo, Sampo, Ohta, Tomoko, Rak, Rafal, Sullivan, Dan, Mao, Chunhong, Wang, Chunxia, Sobral, Bruno, Tsujii, Jun'ichi, Ananiadou, Sophia“…For the ID task, the highest-performing system achieved 56% F-score, comparable to the state-of-the-art performance at the established ST'09 task. In the EPI task, the best result was 53% F-score for the full set of extraction targets and 69% F-score for a reduced set of core extraction targets, approaching a level of performance sufficient for user-facing applications. …”
Publicado 2012
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75429“…The results of our experiments using three representative benchmark datasets show that the PrISE(C )outperforms PrISE(L )and PrISE(G); and that PrISE(C )is highly competitive with state-of-the-art structure-based methods for predicting protein-protein interface residues. …”
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75430por Peltzer, Karl, Naidoo, Pamela, Matseke, Gladys, Louw, Julia, Mchunu, Gugu, Tutshana, Bomkazi“…Data on socio-demographic variables, health status, alcohol and tobacco use and adherence to anti-TB drugs and anti-retroviral therapy (ART) were collected using a structured questionnaire. …”
Publicado 2012
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75431por Landes, Megan, van Lettow, Monique, Chan, Adrienne K., Mayuni, Isabell, Schouten, Erik J., Bedell, Richard A.“…HIV-infected children demonstrated developmental delays, functional health and nutritional deficits that underscore the need for increased uptake of early infant diagnosis and institution of ART for all infected infants.…”
Publicado 2012
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75432por Palacios, R, Lebrón, J, Guerrero-León, M, Del Arco, A, Colmenero, J, Márquez, M, Santos, J“…The median nadir CD4 count was 149/mm(3) (42–232), the median CD4 count at the time of diagnosis of the lung cancer was 237/mm(3) (85–397), and 66.1%<350/mm(3). 66.7% were on ART, and 70% of them had undetectable HIV viral load. …”
Publicado 2012
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75433por Weinblatt, Michael E, Schiff, Michael, Valente, Robert, van der Heijde, Désirée, Citera, Gustavo, Zhao, Cathy, Maldonado, Michael, Fleischmann, RoyEnlace del recurso
Publicado 2013
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75434“…We then prove that these constraints can often lead to significant reductions in the gap between the optimal solution and its non-integral linear programming bound relative to the prior art as well as often substantially faster processing of moderately hard problem instances. …”
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75435por Demers, Jean-Philippe, Sgourakis, Nikolaos G., Gupta, Rashmi, Loquet, Antoine, Giller, Karin, Riedel, Dietmar, Laube, Britta, Kolbe, Michael, Baker, David, Becker, Stefan, Lange, Adam“…We generated a homology model of Shigella flexneri needles compatible with both experimental data: the MxiH solid-state NMR chemical shifts and the state-of-the-art cryoEM density map. These results corroborate the solid-state NMR structure previously solved for Salmonella typhimurium PrgI needles and establish that Shigella flexneri and Salmonella typhimurium subunit proteins adopt a conserved structure and orientation in their assembled state. …”
Publicado 2013
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75436por Petri, Michelle, Wallace, Daniel J, Spindler, Alberto, Chindalore, Vishala, Kalunian, Kenneth, Mysler, Eduardo, Neuwelt, C Michael, Robbie, Gabriel, White, Wendy I, Higgs, Brandon W, Yao, Yihong, Wang, Liangwei, Ethgen, Dominique, Greth, WarrenEnlace del recurso
Publicado 2013
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75437“…We report competitive predictive performance w.r.t. state-of-the-art. Specifically we obtain 0.83 AUC ROC and 0.93 AUC PR in comparison to 0.71 AUC ROC and 0.87 AUC PR previously achieved by the position specific scoring matrices (PSSMs) based SMALI approach. …”
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75438por Mehta, Salil, Mansoor, Homa, Khan, Samsuddin, Saranchuk, Peter, Isaakidis, Petros“…BACKGROUND: The prevalence and the patterns of ocular inflammatory disease and ocular tuberculosis (TB) are largely undocumented among Multidrug Resistant TB (MDR-TB) patients co-infected with Human Immunodeficiency Virus (HIV) and on antituberculosis and antiretroviral therapy (ART). METHODS: Lilavati Hospital and Research Center and Médecins Sans Frontières (MSF) organized a cross-sectional ophthalmological evaluation of HIV/MDR-TB co-infected patients followed in an MSF-run HIV-clinic in Mumbai, India, which included measuring visual acuity, and slit lamp and dilated fundus examinations. …”
Publicado 2013
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75439por Venkatesh, Kartik K., Becker, Jessica E., Kumarasamy, Nagalingeswaran, Nakamura, Yoriko M., Mayer, Kenneth H., Losina, Elena, Swaminathan, Soumya, Flanigan, Timothy P., Walensky, Rochelle P., Freedberg, Kenneth A.“…BACKGROUND: Despite expanding access to antiretroviral therapy (ART), most of the estimated 2.3 to 2.5 million HIV-infected individuals in India remain undiagnosed. …”
Publicado 2013
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75440“…In this paper we utilize the state-of-the-art core diffusion-based step in IsoRank for similarity matrix computation, and couple it with two heuristic bipartite matching algorithms – a matrix-based greedy approach, and a tunable, adaptive, auction-based matching algorithm developed by us. …”
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