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75461“…MATERIALS AND METHODS: Within the PIVOT neurocognitive sub-study, effectively suppressed HIV-infected adults on either standard cART or ritonavir-boosted PI monotherapy completed the Alcohol Use Disorders Identification Test (AUDIT) designed to detect risky alcohol consumption. …”
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75462“…INTRODUCTION: With the advent of combined antiretroviral therapy (cART), more people infected with HIV are living into older age; 22% of adults receiving care in the UK are aged over 50 years [1]. …”
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75463“…The mean CD4 was 560 (range 48-1339). All patients were on ART and 6 (10%) had a detectable viral load > 400 copies/mL. …”
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75464por Valdés, James J“…METHODS: Aided by state-of-the-art, high-throughput computational methods, the current study simulated and analyzed the dynamics of competitive histamine binding at the tick-host interface using the available crystal structures of both the tick salivary lipocalin histamine-binding protein from Rhipicephalus appendiculatus and the human histamine receptor 1. …”
Publicado 2014
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75465por Wang, Shicai, Pandis, Ioannis, Johnson, David, Emam, Ibrahim, Guitton, Florian, Oehmichen, Axel, Guo, Yike“…With high-throughput sequencing technologies promising to produce even larger datasets per subject, we expect the performance of the state-of-the-art statistical algorithms to be further impacted unless efforts towards optimisation are carried out. …”
Publicado 2014
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75466“…CONCLUSIONS: The described network biology workflow uses state-of-the-art pathway and network analysis methods to study the rewiring of the diabetic liver. …”
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75467por Kaiser, Rachel, Tang, Ling Fung, Taylor, Kimberly E, Sterba, Kirsten, Nititham, Joanne, Brown, Elizabeth E, Edberg, Jeffrey C, McGwin, Gerald, Alarcón, Graciela S, Ramsey-Goldman, Rosalind, Reveille, John D, Vilá, Luis M, Petri, Michelle, Rauch, Joyce, Miller, Emily, Mesznik, Kara, Kwok, Pui-Yan, Kimberly, Robert P, Salmon, Jane E, Criswell, Lindsey AEnlace del recurso
Publicado 2014
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75468por Winthrop, Kevin L, Yamanaka, Hisashi, Valdez, Hernan, Mortensen, Eric, Chew, Robert, Krishnaswami, Sriram, Kawabata, Thomas, Riese, RichardEnlace del recurso
Publicado 2014
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75469por Sieper, J, Landewé, R, Rudwaleit, M, van der Heijde, D, Dougados, M, Mease, P J, Braun, J, Deodhar, A, Kivitz, A, Walsh, J, Hoepken, B, Nurminen, T, Maksymowych, W PEnlace del recurso
Publicado 2015
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75470Automated discrimination of lower and higher grade gliomas based on histopathological image analysis“…CONCLUSION: The proposed method demonstrates fairly high accuracy and compares favorably against best-known alternatives such as the state-of-the-art WND-CHARM feature set provided by NIH combined with powerful support vector machine classifier. …”
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75471“…RESULTS: Using Rosetta, a state-of-the-art fragment-based protein structure prediction package, we evaluated our proposed pipeline on 70 former CASP targets containing up to 150 amino acids. …”
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75472por Le, Duc-Hau“…RESULTS: Comparing the predictive performance of our proposed algorithm with that of two state-of-the-art network propagation algorithms including one we used in our previous study, we found that it performed statistically significantly better than that of these two algorithms for all the constructed functional similarity protein complex networks. …”
Publicado 2015
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75473
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75474por Bravo, Àlex, Piñero, Janet, Queralt-Rosinach, Núria, Rautschka, Michael, Furlong, Laura I“…RESULTS: By exploiting morpho-syntactic information of the text, BeFree is able to identify gene-disease, drug-disease and drug-target associations with state-of-the-art performance. The application of BeFree to real-case scenarios shows its effectiveness in extracting information relevant for translational research. …”
Publicado 2015
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75475“…RESULTS: We applied a ‘computational structural genomics’ approach using five state-of-the-art remote similarity detection methods to detect the relationship between uncharacterized DUFs and domain families of known structures. …”
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75476“…An evidence-based approach was used to report on recent advances with potential to advance PM in the context of historical critical and systematic reviews to delineate current state-of-the-art technologies. Special focus was placed on oral microbiome research associated with health and disease states, emerging research domains, and technological advances, which are positioning realization of PM. …”
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75477“…INTRODUCTION: Early HIV testing and timely initiation of ART is critical for the improved quality of life of PLWHIV. …”
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75478por Stone, Katie Alexandra“…Eighteen percent of the total number of people living with HIV eligible for antiretroviral treatment (ART) accessed treatment. Only Malaysia and Indonesia provide OST in prison, with no NSP provision in prisons in the region. …”
Publicado 2015
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75479por Suzan-Monti, Marie, Lorente, Nicolas, Demoulin, Baptiste, Marcellin, Fabienne, Préau, Marie, Dray-Spira, Rosemary, Lert, France, Spire, Bruno“…INTRODUCTION: People living with HIV (PLHIV) on antiretroviral therapy (ART), with sustained undetectable viral load (sUVL) and no history of sexually transmitted infections for at least six months, are considered to have a low risk of HIV transmission (LRT). …”
Publicado 2016
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75480por Kim, Soo Woong“…Although the main goal of the evaluation of the infertile men is to identify the reversible conditions, to identify the irreversible causes that can or cannot be managed by assisted reproductive techniques (ART) is also important. Etiologies for azoospermia can be categorized as pre-testicular, testicular and post-testicular. …”
Publicado 2015
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