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  1. 75481
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    A Randomized, Double‐Blind, Placebo‐Controlled, Sixteen‐Week Study of Subcutaneous Golimumab in Patients With Active Nonradiographic Axial Spondyloarthritis
  2. 75482
    “…Linear regression was used to test the association between genotypes and baseline pre-ART HIV RNA, CD4(+) lymphocyte count, and cognitive score, adjusting for age, race/ethnicity and study. …”
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    Killer Cell Immunoglobulin-Like Receptor Alleles Alter HIV Disease in Children
  3. 75483
    “…The high specificity and thus high positive predictive value would suggest a positive POC result may be adequate for immediate infant ART initiation. While POC testing for EID may have particular utility for birth testing at delivery facilities, the lower sensitivity and error rate requires further attention, as does field implementation of POC EID technologies in other clinical care settings.…”
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    Laboratory Evaluation of the Alere q Point-of-Care System for Early Infant HIV Diagnosis
  4. 75484
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    Phenotypic, Functional, and Gene Expression Profiling of Peripheral CD45RA+ and CD45RO+ CD4+CD25+CD127(low) Treg Cells in Patients With Chronic Rheumatoid Arthritis
  5. 75485
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    QUADrATiC: scalable gene expression connectivity mapping for repurposing FDA-approved therapeutics
  6. 75486
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    Activation‐Induced Killer Cell Immunoglobulin‐like Receptor 3DL2 Binding to HLA–B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis
  7. 75487
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    Suppressive Effects of Insulin on Tumor Necrosis Factor–Dependent Early Osteoarthritic Changes Associated With Obesity and Type 2 Diabetes Mellitus
  8. 75488
    “…We begin by briefly describing the current state-of-the-art in integrating electroactive species on surfaces to control the immobilization of diverse biological entities. …”
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    Electrically Responsive Surfaces: Experimental and Theoretical Investigations
  9. 75489
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    Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti–Cyclic Citrullinated Peptide–Negative Rheumatoid Arthritis
  10. 75490
    “…IMPORTANCE This study describes a robust, state-of-the-art platform developed from available whole-genome sequences of E. coli and Shigella spp. by distilling useful signatures for epidemiology and molecular risk assessment into one assay. …”
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    FDA Escherichia coli Identification (FDA-ECID) Microarray: a Pangenome Molecular Toolbox for Serotyping, Virulence Profiling, Molecular Epidemiology, and Phylogeny
  11. 75491
    por Azad, Ariful, Rajwa, Bartek, Pothen, Alex
    Publicado 2016
    “…With a publicly available data set we demonstrate that flowVS performs as well as the VSN software, a state-of-the-art approach developed for microarrays. CONCLUSIONS: The homogeneity of variance in cell populations across FC samples is desirable when extracting features uniformly and comparing cell populations with different levels of marker expressions. …”
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    flowVS: channel-specific variance stabilization in flow cytometry
  12. 75492
    “…The purpose of the present study is to systematically evaluate the effectiveness of different noise reduction strategies (NRS) using nuisance variables to improve perfusion based FC analysis in two cohorts of healthy adults using state of the art 3D background-suppressed (BS) GRASE pseudo-continuous ASL (pCASL) and dual-echo 2D-EPI pCASL sequences. …”
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    Noise Reduction in Arterial Spin Labeling Based Functional Connectivity Using Nuisance Variables
  13. 75493
    “…The proposed methods demonstrated better convergence properties than state-of-the-art methods employed in systems and computational biology. …”
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    Tailored parameter optimization methods for ordinary differential equation models with steady-state constraints
  14. 75494
    “…CONCLUSIONS: Our algorithms have pushed up the state-of-the-art of EMS solvers and we believe that the techniques introduced in this paper are also applicable to other motif search problems such as Planted Motif Search (PMS) and Simple Motif Search (SMS). …”
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    Efficient sequential and parallel algorithms for finding edit distance based motifs
  15. 75495
    “…This study re-evaluates the state-of-the-art toolkit to diagnose chronic inorganic mercury intoxication by analysing data from multiple pooled cross-sectional studies. …”
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    Essential Indicators Identifying Chronic Inorganic Mercury Intoxication: Pooled Analysis across Multiple Cross-Sectional Studies
  16. 75496
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    Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications
  17. 75497
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    Familial Risk of Sjögren's Syndrome and Co‐aggregation of Autoimmune Diseases in Affected Families: A Nationwide Population Study
  18. 75498
    “…INTRODUCTION: Spermatozoa motility is the critical parameter to affect the treatment outcomes during assisted reproductive technologies (ART), but its reproductive capability remains a little informed in condition of severe male factor infertility. …”
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    Decreased Sperm Motility Retarded ICSI Fertilization Rate in Severe Oligozoospermia but Good-Quality Embryo Transfer Had Achieved the Prospective Clinical Outcomes
  19. 75499
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    Autoantibody‐Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity
  20. 75500
    “…RESULTS: 450 HIV-1-infected adults were evaluated, median age 34 years (IQR 30–40) with a CD4 count 566/mm(3) (IQR 443–724), 70% on antiretroviral therapy (ART). The prevalence of cardiomegaly was 12.7% (95% C.I. 9.6%-15.8%). …”
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    Cardio-Thoracic Ratio Is Stable, Reproducible and Has Potential as a Screening Tool for HIV-1 Related Cardiac Disorders in Resource Poor Settings
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