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75761“…Background: Immune recovery in people living with HIV (PLWHIV) is a residual aspect of antiretroviral treatment (ART) in most patients, but in a non-negligible proportion of them, the CD4+ lymphocytes count, or CD4/CD8 ratio remains suboptimal. …”
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75762por Braccia, Amy, Lau, Jamie, Robinson, Jesse, Croasdaile, Michael, Park, Jeong, Parola, ArtEnlace del recurso
Publicado 2023
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75763por Carvalhaes, Cecilia G., Shortridge, Dee, Woosley, Leah N., Gurung, Nabina, Castanheira, Mariana“…In this study, the performance of the Vitek 2 AES was compared to state-of-the-art methodologies for AST, broth microdilution and β-lactamase gene detection, whole-genome sequencing, against a collection of 513 Enterobacterales clinical isolates harboring various β-lactamase genes, including carbapenemase, ESBL, and transferrable AmpC genes, from 73 medical centers in 7 countries in North and Latin America.…”
Publicado 2023
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75764por Rudas, Akos, Chiang, Jeffrey N., Corradetti, Giulia, Rakocz, Nadav, Avram, Oren, Halperin, Eran, Sadda, Srinivas R.“…We found that not only can we show that the machine-read OCT B-scan biomarkers are predictive of AMD progression, we also observe that our proposed combined OCT and EHR data-based algorithm outperforms the state-of-the-art solution in clinically relevant metrics and provides actionable information which has the potential to improve patient care. …”
Publicado 2023
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75765
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75766por Kolk, Maarten Z.H., Deb, Brototo, Ruipérez-Campillo, Samuel, Bhatia, Neil K., Clopton, Paul, Wilde, Arthur A.M., Narayan, Sanjiv M., Knops, Reinoud E., Tjong, Fleur V.Y.“…METHODS: This systematic review and exploratory meta-analysis assesses the state-of-the-art of ML/DL models of electrophysiological signals for personalised prediction of malignant VA or SCD, and studies potential causes of bias (PROSPERO, reference: CRD42021283464). …”
Publicado 2023
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75767“…We also investigate the state-of-the-art blood transcriptomic breast cancer research aimed at bringing novel blood transcriptome biomarkers and next-generation sequencing technology into clinical practice. …”
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75768por Varone, Giuseppe, Ieracitano, Cosimo, Çiftçioğlu, Aybike Özyüksel, Hussain, Tassadaq, Gogate, Mandar, Dashtipour, Kia, Al-Tamimi, Bassam Naji, Almoamari, Hani, Akkurt, Iskender, Hussain, Amir“…Comparative results showed that our proposed HELM architecture outperformed state-of-the-art SVM, decision tree, polynomial regressor, random forest, MLP, CNN, and conventional ELM models. …”
Publicado 2023
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75769por Mughal, Sadaf Rasheed, Niazi, Sadia Ambreen, Do, Thuy, Gilbert, Steven C., Didelot, Xavier, Radford, David R., Beighton, David“…The aim of this study was to investigate and clarify the ambiguous taxonomy of Actinomyces naeslundii and its closely related species using state-of-the-art high-throughput sequencing techniques, and, furthermore, to determine whether sub-clusters identified within Actinomyces oris and Actinomyces naeslundii in a previous study by multi locus sequence typing (MLST) using concatenation of seven housekeeping genes should either be classified as subspecies or distinct species. …”
Publicado 2023
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75770por Li, Sile, Yim, Man Kin, Yip, Ka Lai, Xiao, Chuanyun, Luk, Ho Yin, Xiao, Sijia, Chen, Zigui, Chan, Paul K. S., Boon, Siaw Shi“…Our findings are vital for the designing of state-of-the-art therapies for HPV-associated cancers.…”
Publicado 2023
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75771“…METHODS: Two electronic databases were screened by title and abstract to summarize the state of art on FOG and fall detection with any wearable technology among patients with PD. …”
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75772por Grajeda-Rosado, Ruth María, Levet-Nofrietta, Alejandro, Mondragón-Olan, Max, Velázquez-Sanabia,, Carlos“…, para responder esto, se utiliza una metodología de revisión documental, que incluye el estado del arte de la morfología propia del fenómeno, enumeración de las investigaciones realizadas dentro del territorio mexicano que buscan medir las isotermas de la ICU, una revisión histórica de la introducción de la ICU como indicador de sustentabilidad y resiliencia, y por último, revisión del impacto de las investigación sobre las políticas que se aplican al área urbanística. …”
Publicado 2023
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75773por Ruamtawee, Witchakorn, Tipayamongkholgul, Mathuros, Aimyong, Natnaree, Manosuthi, Weerawat“…BACKGROUND: Cardiovascular diseases (CVD) due to atherosclerosis have become one of the major causes of death among people living with HIV (PLHIV) since effective antiretroviral therapy (ART) has been available throughout the world. However, the epidemiologic evidence of this problem from the Asia-Pacific region remains unclear. …”
Publicado 2023
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75774por Becker, Benjamin V., Kaatsch, Hanns Leonhard, Nestler, Kai, Overhoff, Daniel, Schneider, Julian, Dillinger, Daniel, Piechotka, Joel, Brockmann, Marc A., Ullmann, Reinhard, Port, Matthias, Scherthan, Harry, Waldeck, Stephan“…. • Retrospective single-center study showed superior general image quality accompanied by higher dose exposure in initial abdominal PCCT protocols compared to state-of-the-art conventional CT. • A simultaneous ex vivo phantom study revealed correspondingly increased frequencies of DNA double-strand breaks after PCCT. …”
Publicado 2022
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75775por Ngoufack Jagni Semengue, Ezechiel, Santoro, Maria Mercedes, Ndze, Valantine Ngum, Ka’e, Aude Christelle, Yagai, Bouba, Nka, Alex Durand, Dambaya, Beatrice, Takou, Desiré, Teto, Georges, Fabeni, Lavinia, Colizzi, Vittorio, Perno, Carlo-Federico, Ceccherini-Silberstein, Francesca, Fokam, Joseph“…As sub-Saharan Africa (SSA) countries are transitioning to dolutegravir (DTG)-based ART, baseline data are required for optimal monitoring of therapeutic response. …”
Publicado 2022
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75776por Xia, Xinru, Zhang, Yuan, Cao, Meng, Yu, Xiang, Gao, Li, Qin, Lianju, Wu, Wei, Cui, Yugui, Liu, Jiayin“…The expressions of CLDN3, AQP8, SCNN1β in RL95-2 cell line were significantly depressed by the superphysiological E2, ERα agonist or ERβ agonist, which could be reversed by the oestrogen receptor antagonist. CONCLUSION: ART-induced hyperoestrogenism reduces CLDN3, AQP8 and SCNN1β expression through ERα, thereby destroying tight junctions and water and sodium channels in the endometrial cavity epithelium, which may cause abnormal implantation due to abnormal uterine fluid secretion and absorption.…”
Publicado 2023
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75777“…In doing so, the first steps are taken in advancing the state of the art of knowledge regarding personalized serious games in health care. …”
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75778por Sengupta, Arunima, Dorn, Aurélien, Jamshidi, Mohammad, Schwob, Magali, Hassan, Widad, De Maddalena, Lea Lara, Hugi, Andreas, Stucki, Andreas O., Dorn, Patrick, Marti, Thomas M., Wisser, Oliver, Stucki, Janick D., Krebs, Tobias, Hobi, Nina, Guenat, Olivier T.“…The Cloud α AX12 model thus represents a state-of-the-art pre-clinical tool to study inhalation toxicity risks, drug safety and efficacy.…”
Publicado 2023
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75779por Zhang, Yu, Lu, Peng, Wu, Kai, Zhou, Hongxi, Yu, Haibing, Yuan, Ju, Dong, Lang, Liu, Qiao, Lu, Wei, Yang, Haitao, Cao, Dianyi, Zhu, Limei“…RESULTS: A total of 340 prisoners were included, 89.7% were male, the median age was 38 years [Interquartile Range (IQR):32-46 years], these patients were on Antiviral Therapy (ART), and median CD4 counts was 376 (IQR: 261-496), 103 (30.3%) were positive in at least one test, LTBI by TST was 16.5%, LTBI by EC was 15.9%, LTBI by QFT was 26.2%. …”
Publicado 2023
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75780por Sun, Peng, Zhao, Yao, Men, Jie, Ma, Zhe-Ru, Jiang, Hao-Zhuo, Liu, Cheng-Yan, Feng, Wei“…BACKGROUND: Virtual and augmented reality (VAR) represents a combination of current state-of-the-art computer and imaging technologies and has the potential to be a revolutionary technology in many surgical fields. …”
Publicado 2023
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