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75981por Ermel, A., Tonui, P., Titus, M., Tong, Y., Wong, N., Ong’echa, J., Muthoka, K., Kiptoo, S., Moormann, A., Hogan, J., Mwangi, A., Cu-Uvin, S., Loehrer, P. J., Orang’o, O., Brown, D.“…CONCLUSION: HIV infection, more lifetime sexual partners, and greater distance to health-care were associated with a higher risk of oncogenic HPV detection, in spite of ART use in those who were HIV-infected. Counseling of women about sexual practices, improved access to health-care facilities, and vaccination against HPV are all potentially important in reducing oncogenic HPV infections.…”
Publicado 2019
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75982por Thiébaut, Rodolphe, Hejblum, Boris P., Hocini, Hakim, Bonnabau, Henri, Skinner, Jason, Montes, Monica, Lacabaratz, Christine, Richert, Laura, Palucka, Karolina, Banchereau, Jacques, Lévy, Yves“…We previously reported that vaccination with ex vivo generated Dendritic Cells (DC) loaded with HIV-lipopeptides in HIV-infected patients (n = 19) on antiretroviral therapy (ART) was well-tolerated and immunogenic. Vaccine-elicited HIV-specific T cell responses were associated with improved control of viral replication following antiretroviral interruption (ATI from w24 to w48). …”
Publicado 2019
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75983por Blanco, José-Ramón, Barrio, Inmaculada, Ramalle-Gómara, Enrique, Beltran, María Isabel, Ibarra, Valvanera, Metola, Luis, Sanz, Mercedes, Oteo, José A., Melús, Estrella, Antón, Lucía“…METHODS: This was a prospective cross-sectional study of HIV-infected people aged ≥18 years on a stable antiretroviral regimen (ART) ≥1 year. Frailty was defined by ≥3 of 5 Fried's criteria: weight loss, low physical activity, exhaustion, weak grip strength and slow walking time. …”
Publicado 2019
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75984“…Graph-based methods enable sequence variant genotyping from variation-aware reference genomes that may incorporate cohort-specific sequence variants, which is not possible with the current implementation of state-of-the-art methods that rely on linear reference genomes. …”
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75985“…Without relying on large-scale labeled training data or requiring any custom training, our model can be efficiently generalized to new synonyms and performs as well or better than state-of-the-art methods custom built for specific ontologies.…”
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75986por Chou, Yi-Chen, Lao, I-Ha, Hsieh, Pei-Ling, Su, Ying-Ying, Mak, Chee-Wai, Sun, Ding-Ping, Sheu, Ming-Jen, Kuo, Hsing-Tao, Chen, Tzu-Ju, Ho, Chung-Han, Kuo, Yu-Ting“…BACKGROUND: Although important for determining long-term outcome, pathologic stage of hepatocellular carcinoma (HCC) is difficult to predict before surgery. Current state-of-the-art magnetic resonance imaging (MRI) using gadoxetic acid provides many imaging features that could potentially be used to classify single HCC as pT1 or pT2. …”
Publicado 2019
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75987por Khajanchi, Bijay K., Xu, Joshua, Grim, Christopher J., Ottesen, Andrea R., Ramachandran, Padmini, Foley, Steven L.“…Conversely, ferritin, ferrous iron transport protein A (feoA), IncFIB-encoded IS1 and acrR/tetR transposases and ArtA toxin of WT were downregulated in ID conditions. …”
Publicado 2019
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75988por Pérez-Pérez, Martin, Pérez-Rodríguez, Gael, Blanco-Míguez, Aitor, Fdez-Riverola, Florentino, Valencia, Alfonso, Krallinger, Martin, Lourenço, Anália“…BACKGROUND: Shared tasks and community challenges represent key instruments to promote research, collaboration and determine the state of the art of biomedical and chemical text mining technologies. …”
Publicado 2019
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75989por Hani, Lylia, Chaillon, Antoine, Nere, Marie-Laure, Ruffin, Nicolas, Alameddine, Joudy, Salmona, Maud, Lopez Zaragoza, José-Luiz, Smith, Davey M., Schwartz, Olivier, Lelièvre, Jean-Daniel, Delaugerre, Constance, Lévy, Yves, Seddiki, Nabila“…We sorted memory CD4(+)CD45RO(+)SAMHD1(low), CD4(+)CD45RO(+)SAMHD1(+) and naive CD4(+)CD45RO(-)SAMHD1(+) cells from HIV-1-infected patients on anti-retroviral therapy (c-ART) and performed HIV-1 DNA quantification, ultra-deep-sequencing of partial env (C2/V3) sequences and phenotypic characterization of the cells. …”
Publicado 2019
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75990por Lebina, Limakatso, Seatlholo, Ntombexolo, Taruberekera, Noah, Radebe, Mopo, Kinghorn, Anthony, Meyer, Tessa, Mhazo, Miriam, Otwombe, Kennedy, Hlongwane, Khuthadzo, Ringane, Ashley, Koloane, Nthabiseng, Nkuta, Mbali, Nkhwashu, Nkhensani, Farirai, Thato, Kweza, Patience, Chidarikire, Thato, Shamu, Simukai, Kufa, Tendesayi, Puren, Adrian, Martinson, Neil, Milovanovic, Minja“…Of those newly diagnosed with HIV, 16% (12/75) were initiated on ART. Almost half (48.0%; 543/1131) of those tested were linked to a primary HIV test as follows: supervised (85.2%; 336/394); semi-supervised (93.8%; 91/97) and unsupervised (18.1%; 116/640). …”
Publicado 2019
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75991por Phillips, Andrew N, Cambiano, Valentina, Nakagawa, Fumiyo, Bansi‐Matharu, Loveleen, Wilson, David, Jani, Ilesh, Apollo, Tsitsi, Sculpher, Mark, Hallett, Timothy, Kerr, Cliff, van Oosterhout, Joep J, Eaton, Jeffrey W, Estill, Janne, Williams, Brian, Doi, Naoko, Cowan, Frances, Keiser, Olivia, Ford, Deborah, Hatzold, Karin, Barnabas, Ruanne, Ayles, Helen, Meyer‐Rath, Gesine, Nelson, Lisa, Johnson, Cheryl, Baggaley, Rachel, Fakoya, Ade, Jahn, Andreas, Revill, Paul“…METHODS: We simulated a series of setting‐scenarios for adult HIV epidemics and ART programmes typical of settings in southern Africa using an individual‐based model and projected forward from 2018 under two policies: (i) a minimum package of “core” testing (i.e. testing in pregnant women, for diagnosis of symptoms, in sex workers, and in men coming forward for circumcision) is conducted, and (ii) core‐testing as above plus additional testing beyond this (“additional‐testing”), for which we specify different rates of testing and various degrees to which those with HIV are more likely to test than those without HIV. …”
Publicado 2019
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75992por Liu, Xuemei, Zhang, Wei, Xu, Yanping, Chu, Yongli, Wang, Xinrong, Li, Qian, Ma, Zhi, Liu, Zhenteng, Wan, Yanling“…It seems that vitamin D is associated with clinical pregnancy outcomes of assisted reproductive technologies (ART), but its role remains elusive. This study is aimed to establish whether vitamin D is associated with clinical outcomes of in vitro fertilization (IVF). …”
Publicado 2019
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75993“…It has been widely used and regarded as the state-of-the-art constitutive law for myocardium. However, there has been no analysis to show if it has both adequate descriptive and predictive capabilities for other tissue tests of myocardium. …”
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75994por Kanoulas, Evangelos, Butler, Mairead, Rowley, Caitlin, Voulgaridou, Vasiliki, Diamantis, Konstantinos, Duncan, William Colin, McNeilly, Alan, Averkiou, Michalakis, Wijkstra, Hessel, Mischi, Massimo, Wilson, Rhodri Simon, Lu, Weiping, Sboros, Vassilis“…The method reduces the examination times to a few minutes using state-of-the-art ultrasound equipment and can provide super-resolution maps for an entire prostate with similar resolution to that achieved in other studies.…”
Publicado 2019
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75995por Banin, Andrew N, Tuen, Michael, Bimela, Jude S, Tongo, Marcel, Zappile, Paul, Khodadadi‐Jamayran, Alireza, Nanfack, Aubin J, Okonko, Iheanyi O, Meli, Josephine, Wang, Xiaohong, Mbanya, Dora, Ngogang, Jeanne, Gorny, Miroslaw K, Heguy, Adriana, Fokunang, Charles, Duerr, Ralf“…URF pol genomic analysis revealed a number of accessory drug resistance mutations (DRMs) in the ART‐naïve participants. Genotypic env analysis suggests CCR5 usage in 14/18 samples and identified deviations at residues, critical for gp120/gp41 interphase and CD4 binding site broadly neutralizing antibodies in more than half of the studied URFs. …”
Publicado 2019
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75996por Amstutz, Alain, Lejone, Thabo Ishmael, Khesa, Lefu, Muhairwe, Josephine, Nsakala, Bienvenu Lengo, Tlali, Katleho, Bresser, Moniek, Vanobberghen, Fiona, Kopo, Mathebe, Kao, Mpho, Klimkait, Thomas, Battegay, Manuel, Labhardt, Niklaus Daniel, Glass, Tracy Renée“…The HOSENG trial is linked to the VIBRA (Village-Based Refill of ART) trial. Together, they constitute the GET ON (GETting tOwards Ninety) research project. …”
Publicado 2019
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75997por Grilli, Stephan T., Tappin, David R., Carey, Steven, Watt, Sebastian F. L., Ward, Steve N., Grilli, Annette R., Engwell, Samantha L., Zhang, Cheng, Kirby, James T., Schambach, Lauren, Muin, Muslim“…Here, we present numerical simulations of the tsunami, with state-of the-art numerical models, based on a combined landslide-source and bathymetric dataset. …”
Publicado 2019
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75998por Fleischmann, Max, Martin, Daniel, Peña-Llopis, Samuel, Oppermann, Julius, von der Grün, Jens, Diefenhardt, Markus, Chatzikonstantinou, Georgios, Fokas, Emmanouil, Rödel, Claus, Strebhardt, Klaus, Becker, Sven, Rödel, Franz, Tselis, Nikolaos“…Introduction: Definitive chemoradiation (CRT) followed by high-dose-rate (HDR) brachytherapy (BT) represents state-of-the-art treatment for locally-advanced cervical cancer. …”
Publicado 2019
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75999por Opio, Denis, Semitala, Fred C., Kakeeto, Alex, Sendaula, Emmanuel, Okimat, Paul, Nakafeero, Brenda, Nankabirwa, Joaniter I., Karamagi, Charles, Kalyango, Joan N.“…METHODS: This was a retrospective cohort study that involved the review of 646 records of patients initiated on antiretroviral therapy (ART) between January 1st, 2015 and December 31st, 2017 at 13 randomly selected public health facilities in Wakiso district. …”
Publicado 2019
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76000por Sarno, A., Andreozzi, E., De Caro, D., Di Meo, G., Strollo, A. G. M., Cesarelli, M., Bifulco, P.“…The NVCA filter performances were compared to those achieved by simple moving average filters and the state-of-the-art video denoising block matching-4D (VBM4D) algorithm. …”
Publicado 2019
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