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76101por Kone, Bourahima, Goita, Drissa, Dolo, Oumar, Traore, Daouda, Sogoba, Dramane, Somboro, Amadou, Sanogo, Moumine, Somboro, Anou M, Coulibaly, Nadie, Sanogo, Alou, Diarra, Zoumana, Traore, Madou, Maiga, Almoustapha I, Baya, Bocar, Sarro, Yeya Dit Sadio, Diarra, Bassirou, Kone, Amadou, Diallo, Dramane, Dabitao, Djeneba, Holl, Jane L., Belson, Michael, Dao, Sounkalo, Murphy, Robert L., Diakite, Mahamadou, Diallo, Souleymane, Doumbia, Seydou, Maiga, Mamoudou“…BACKGROUND: Routine monitoring of HIV-1 Viral Load (VL) is important in patients on Antiretroviral Therapy (ART) management. Access to HIV VL remains a challenge in resource-limited settings, especially in rural areas. …”
Publicado 2020
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76102“…BACKGROUND: Transformer is an attention-based architecture proven the state-of-the-art model in natural language processing (NLP). …”
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76103“…It is recommended that academic institutions implement state of art technology to bridge the gap between traditional and online learning methods during the pandemic. …”
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76104por Lu, Danfeng, Zhang, Jian-Bo, Wang, Yue-Xin, Geng, Shi-Tao, Zhang, Zunyue, Xu, Yu, Li, Shao-You, Wang, Kun-Hua, Kuang, Yi-Qun“…BACKGROUND: CD4(+) T cell counts in certain human immunodeficiency virus (HIV)-infected patients called immunological non-responders (INRs) could not return to a normal level even with sustained antiretroviral therapy (ART) because of persistent immune activation, which is associated with pro-inflammatory cytokines production and an altered intestinal microbiome profile. …”
Publicado 2021
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76105por van Haaren, M. M., McCoy, L. E., Torres, J. L., Lee, W., Cottrell, C. A., Copps, J. L., van der Woude, P., Yasmeen, A., de Taeye, S. W., Torrents de la Peña, A., Moore, J. P., Burton, D. R., Klasse, P. J., Ward, A. B., Sanders, R. W., van Gils, M. J.“…A better understanding of the humoral immune responses elicited by immunization with state-of-the-art HIV-1 immunogens should facilitate the design of improved HIV-1 vaccine candidates. …”
Publicado 2021
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76106por van Praagh, Gijs D., van der Werf, Niels R., Wang, Jia, van Ommen, Fasco, Poelhekken, Keris, Slart, Riemer H.J.A., Fleischmann, Dominik, Greuter, Marcel J.W., Leiner, Tim, Willemink, Martin J.“…Image data were acquired with four state‐of‐the‐art CT systems using routine CAC scoring acquisition protocols. …”
Publicado 2021
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76107por Mervin, Lewis H., Trapotsi, Maria-Anna, Afzal, Avid M., Barrett, Ian P., Bender, Andreas, Engkvist, Ola“…In order to improve upon the current state-of-the-art, we herein present a novel approach toward predicting protein–ligand interactions using a Probabilistic Random Forest (PRF) classifier. …”
Publicado 2021
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76108“…CONCLUSIONS: We proposed a novel integrative enrichment analysis method based on artificial neuron (IEAAN), which displays better prediction precision of disease-associated genes in comparison with the state-of-the-art statistical-based methods. Our comprehensive evaluation suggests that genes differentially expressed between striatum and liver tissues of health individuals are more likely to be Huntington’s disease-associated genes. …”
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76109por Dommaraju, Sagar, Hagey, Jill, Odeny, Thomas A., Okaka, Sharon, Kadima, Julie, Bukusi, Elizabeth A., Cohen, Craig R., Kwena, Zachary, Eshun-Wilson, Ingrid, Geng, Elvin“…Likewise, patients strongly preferred longer intervals between both clinical reviews (RU = 40.1 and -50.7 for 6- and 1-month spacing, respectively; p < 0.05) and between ART collections (RU = 33.6 and -49.5 for 6- and1-month spacing, respectively; p < 0.05). …”
Publicado 2021
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76110“…The applied experiments reported state-of-the-art metrics. VGG16 reported 100% WS metric (i.e., 0.0097, 99.78%, 0.9984, 99.89%, 99.78%, and 0.9996 for the loss, accuracy, F1, precision, recall, and AUC respectively) concerning the highest WS. …”
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76111“…Experimental results shown that LPFS performs better in comparison with the-state-of-art methods. GO and KEGG enrichment analysis of key gene sets shown that TGF-beta signaling pathway, cytokine-cytokine receptor interaction, immune response, and inflammatory response were gradually affected during the Huntington’s disease progression. …”
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76112por Vassolo, Roberto Santiago, Mac Cawley, Alejandro Francisco, Tortorella, Guilherme Luz, Fogliatto, Flavio Sanson, Tlapa, Diego, Narayanamurthy, Gopalakrishnan“…BACKGROUND: Alternative approaches to analyzing and evaluating health care investments in state-of-the-art technologies are being increasingly discussed in the literature, especially with the advent of Healthcare 4.0 (H4.0) technologies or eHealth. …”
Publicado 2021
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76113por Magrelli, Silvia, Valentini, Piero, De Rose, Cristina, Morello, Rosa, Buonsenso, Danilo“…In this study, we trained from scratch four state-of-the-art deep-learning models (VGG19, Xception, Inception-v3 and Inception-ResNet-v2) for detecting children with bronchiolitis and pneumonia. …”
Publicado 2021
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76114“…Experimental results show that the momentum factor biogeography-based optimization can improve the detection performance of the state-of-the-art approaches in terms of overall accuracy. In future research, we will continue to use and improve other global optimization algorithms to enhance the application ability of deep learning in medical pathological image detection.…”
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76115por Overbergh, Thomas, Severijns, Pieter, Beaucage-Gauvreau, Erica, Ackermans, Thijs, Moke, Lieven, Jonkers, Ilse, Scheys, Lennart“…Image-based subject-specific models and simulations are recently being introduced to complement current state-of-the-art mostly static insights of the adult spinal deformity (ASD) pathology and improve the often poor surgical outcomes. …”
Publicado 2021
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76116por Rakic, Milenko, Jaboyedoff, Manon, Bachmann, Sara, Berger, Christoph, Diezi, Manuel, do Canto, Philipp, Forrest, Christopher B., Frey, Urs, Fuchs, Oliver, Gervaix, Alain, Gluecksberg, Amalia Stefani, Grotzer, Michael, Heininger, Ulrich, Kahlert, Christian R., Kaiser, Daniela, Kopp, Matthias V., Lauener, Roger, Neuhaus, Thomas J., Paioni, Paolo, Posfay-Barbe, Klara, Ramelli, Gian Paolo, Simeoni, Umberto, Simonetti, Giacomo, Sokollik, Christiane, Spycher, Ben D., Kuehni, Claudia E.“…KEY HIGHLIGHTS: The symposium consisted of state-of-the-art lectures from national and international keynote speakers, workshops and plenary discussions. …”
Publicado 2021
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76117por Nalubega, Sylivia, Kyenkya, Joshua, Bagaya, Irene, Nabukenya, Sylvia, Ssewankambo, Nelson, Nakanjako, Damalie, Kiragga, Agnes N.“…We recommend community-based models such as drop out centres, peer facilitated distribution and community outreaches as alternative measures for access to ART during the COVID-19 pandemic. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12879-021-06684-6.…”
Publicado 2021
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76118“…We describe 12-month treatment outcomes among multimorbid patients attending integrated antiretroviral treatment (ART) and NCD clubs in Cape Town, South Africa. METHODS: As part of an integrated clubs (IC) model pilot implemented in 2016 by the local government at two primary health care clinics in Cape Town, we identified all multimorbid patients who were enrolled for IC for at least 12 months by August 2017. …”
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76119por De La Vega, Francisco M., Chowdhury, Shimul, Moore, Barry, Frise, Erwin, McCarthy, Jeanette, Hernandez, Edgar Javier, Wong, Terence, James, Kiely, Guidugli, Lucia, Agrawal, Pankaj B., Genetti, Casie A., Brownstein, Catherine A., Beggs, Alan H., Löscher, Britt-Sabina, Franke, Andre, Boone, Braden, Levy, Shawn E., Õunap, Katrin, Pajusalu, Sander, Huentelman, Matt, Ramsey, Keri, Naymik, Marcus, Narayanan, Vinodh, Veeraraghavan, Narayanan, Billings, Paul, Reese, Martin G., Yandell, Mark, Kingsmore, Stephen F.“…For comparison, we also analyzed these cases with current state-of-the-art variant prioritization tools. Included in the comparisons were trio, duo, and singleton cases. …”
Publicado 2021
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76120por Kasper, Philipp, Nhlema, Angellina, de Forest, Andrew, Tweya, Hannock, Chaweza, Thom, Mwagomba, Beatrice Matanje, Mula, Adam M., Chiwoko, Jane, Neuhann, Florian, Phiri, Sam, Steffen, Hans-Michael“…BACKGROUND: Cardiovascular disease and especially hypertension are a growing problem among people living with HIV (PLHIV) on antiretroviral therapy (ART) in sub-Saharan Africa. OBJECTIVES: As robust data on hypertension phenotypes associated with distinct cardiovascular risks among PLHIV are limited, we aimed to assess the frequency of white-coat (WCH), masked (MH) hypertension, and blood pressure dipping-patterns in a group of Malawian PLHIV. …”
Publicado 2021
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