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  1. 76121
    “…We demonstrate the SBBs perform on-par or better than the state-of-the-art methods in biomarker discovery and phenotype prediction. …”
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    Improved detection of disease-associated gut microbes using 16S sequence-based biomarkers
  2. 76122
    “…BACKGROUND: Youth Living with HIV (YLWH) have reduced adherence to antiretroviral therapy (ART) and worse virologic outcomes compared to children and adults. …”
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    Feasibility and acceptability of a peer youth led curriculum to improve HIV knowledge in Northern Tanzania: resilience and intervention experience from the perspective of peer leaders
  3. 76123
    “…Antiretroviral therapy (ART) with suppressed viral load (VL) was protective in the unadjusted model but not adjusted multivariate model. …”
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    Prevalence and risk factors associated with HIV and syphilis co-infection in the African Cohort Study: a cross-sectional study
  4. 76124
    “…BACKGROUND: The application of artificial oocyte activation (AOA) after intracytoplasmic sperm injection (ICSI) is successful in mitigating fertilization failure problems in assisted reproductive technology (ART). Nevertheless, there is no relevant study to investigate whether AOA procedures increase developmental risk by disturbing subsequent gene expression at different embryonic development stages. …”
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    DNA methylation and gene expression changes in mouse pre- and post-implantation embryos generated by intracytoplasmic sperm injection with artificial oocyte activation
  5. 76125
    “…BACKGROUND: Combination antiretroviral treatment (cART) cannot eradicate HIV-1 from the body due to the establishment of persisting viral reservoirs which are not affected by therapy and reinitiate new rounds of HIV-1 replication after treatment interruption. …”
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    IRF7 and RNH1 are modifying factors of HIV-1 reservoirs: a genome-wide association analysis
  6. 76126
    “…Eligible participants were adults (aged ≥15 years) who had a new HIV diagnosis, who self-reported being antiretroviral therapy (ART) naïve, and who had consented to recency testing. …”
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    Recent infections among individuals with a new HIV diagnosis in Rwanda, 2018–2020
  7. 76127
    “…Government and non-governmental healthcare systems should be evaluating weight loss agents for inclusion within ART programmes. DISCLOSURES: All Authors: No reported disclosures…”
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    891. Minimum Manufacturing Costs and National Prices for Weight Loss Treatments, as Potential Mitigation for Anti-Retroviral Related Weight Gain in HIV
  8. 76128
    “…Kidney medicine should remain ‘an art’ and will never be just ‘a science’.…”
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    Choices in hemodialysis therapies: variants, personalized therapy and application of evidence-based medicine
  9. 76129
    “…RESULTS: In this study, blood samples were obtained from well-suppressed ART-experienced HIV-1 patients monitored in Uganda (n = 62) or the U.S. …”
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    Reduced and highly diverse peripheral HIV-1 reservoir in virally suppressed patients infected with non-B HIV-1 strains in Uganda
  10. 76130
    “…Plant metabolomics in this study aims at discovering differential metabolites and comprehensively assessing the chemical constituents by combining state-of-the-art high-resolution UPLC-Q/TOF–MS/MS technique and multivariate data analysis. …”
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    Comparison of blood tonic efficacy and chemical constituents of Kadsura interior A.C. Smith and its closely related species
  11. 76131
    “…The accuracy of the proposed method was compared to the accuracies of other state-of-the-art methods, and the highest classification accuracies of [Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text] , [Formula: see text] , 99.67[Formula: see text] and 99.91[Formula: see text] in the detection of MR, MS, ASD, NM, AS, AR and VSD sounds were achieved by setting [Formula: see text] to 0.87,0.65,0.67,0.65,0.67,0.79 and 0.87, respectively.…”
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    A novel intelligent system based on adjustable classifier models for diagnosing heart sounds
  12. 76132
    “…Digital stories are a narrative-based art form often created by individuals without formal training in filmmaking to relate personal experiences. …”
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    Exploring Empathy and Compassion Using Digital Narratives (the Learning to Care Project): Protocol for a Multiphase Mixed Methods Study
  13. 76133
    “…The imaging protocol consisted of a 60-min PET list-mode acquisition with parallel MRI acquisitions, including 3-dimensional time-of-flight MR angiography, MRI navigators, and a T1-weighted MRI scan. State-of-the-art MRI-based attenuation correction was derived from T1-weighted MRI (pseudo-CT [pCT]). …”
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    Promise of Fully Integrated PET/MRI: Noninvasive Clinical Quantification of Cerebral Glucose Metabolism
  14. 76134
    “…CONCLUSION: Serial in vivo evaluations of microcirculation status using state-of-the-art CMR and invasive CFR show that anthracyclines treatment is associated with progressive and irreversible damage to the microcirculation. …”
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    Coronary microcirculation damage in anthracycline cardiotoxicity
  15. 76135
    “…Therefore, we undertook a comprehensive, multi-modal 3T and 7T MRI randomized controlled trial (Netherlands Trial Register - NL5847) in which we randomized 52 young, non-athletic volunteers to a 12-week low- or high-intensity exercise program. Using state-of-the-art methods, we investigated changes in hippocampal volume, as well as changes in vasculature, neuro-metabolites, and peripheral growth factors as potential underpinnings. …”
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    A Randomized Controlled Trial on the Effects of a 12-Week High- vs. Low-Intensity Exercise Intervention on Hippocampal Structure and Function in Healthy, Young Adults
  16. 76136
    “…On account of the impacts of GTD and treatments as well as patient anxiety, large numbers of couples turn to assisted reproductive technology (ART), especially in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). …”
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    Association between gestational trophoblastic disease (GTD) history and clinical outcomes in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles
  17. 76137
    “…CONCLUSIONS: This project is a proof-of-concept integration to demonstrate viability over 6 months and guide future studies to develop these state-of-the-art technologies to help frontline health care workers work in complex moral contexts. …”
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    Digital Interventions to Reduce Distress Among Health Care Providers at the Frontline: Protocol for a Feasibility Trial
  18. 76138
    “…While successful state-of-the art cognitive behavioral interventions exist, there is still a lack of available experts for treatment at home, where most symptoms manifest. …”
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    Internet-based psychotherapy in children with obsessive-compulsive disorder (OCD): protocol of a randomized controlled trial
  19. 76139
    “…ASIC-E4 study (“Beta-Amyloid, Synaptic loss, Inflammation and Cognition in healthy APOE ε4 carriers”) combines state-of-the-art neuroimaging and fluid-based biomarker measurements to study the early interplay of three key pathological features of AD, i.e., beta-amyloid (Aβ) deposition, neuroinflammation and synaptic dysfunction and loss in cognitively normal volunteers with three different levels of genetic (APOE-related) risk for late-onset AD. …”
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    ASIC-E4: Interplay of Beta-Amyloid, Synaptic Density and Neuroinflammation in Cognitively Normal Volunteers With Three Levels of Genetic Risk for Late-Onset Alzheimer's Disease – Study Protocol and Baseline Characteristics
  20. 76140
    “…This study aims at framing the state of the art of the literature about the use of m-health in supporting PASA, as a user-centric innovation strategy, to promote co-production health policies aiming at CVD prevention. …”
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    Mobile-Health based physical activities co-production policies towards cardiovascular diseases prevention: findings from a mixed-method systematic review
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