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  1. 76941
    “…Being on ARV treatment significantly reduced the risk of developing an STD (IRR 0.37, 95% CI 0.32–0.43) compared to ART-naïve people, even in the situation of temporary interruption of treatment (IRR 0.51, 95% CI 0.39–0.43) (see Figure 1). …”
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    Increased incidence of sexually transmitted diseases in the recent years: data from the ICONA cohort
  2. 76942
    “…RESULTS: A total of 413 patients [77% males, median age 46 (IQR 39–52), 17% with past AIDS-defining events, 19% past IDU, 3% with diabetes, 94% on cART, 90% with HIV RNA <50 copies/mL, 18% co-infected with HCV] were enrolled. …”
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    Liver fibrosis is associated with cognitive impairment in HIV-positive patients
  3. 76943
    “…INTRODUCTION: We report interim 24-weeks efficacy data of ATLAS-M trial, a phase IV, multicentre, open-label, randomized study designed to show 48-weeks, non-inferior efficacy (margin of −12%) of treatment simplification to atazanavir/ritonavir (ATV/r)+lamivudine (3TC) versus maintaining 3-drugs ATV/r-based cART. METHODS: Subjects on ATV/r+2 NRTIs, without previous treatment failure (TF), with HIV-RNA <50copies/mL for >3 months and CD4>200 cells/mm(3) for >6 months were eligible. …”
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    Simplification to atazanavir/ritonavir+lamivudine in virologically suppressed HIV-infected patients: 24-weeks interim analysis from ATLAS-M trial
  4. 76944
    “…Like elsewhere in Africa, there is no routine viral load testing, making it difficult to get sensitive analysis of data on ART efficacy within routine clinical practice. Nevertheless, this observational study is reassuring in terms of efficacy of both ATV/r and LPV/r for patients failing first line therapy in our setting.…”
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    Boosted lopinavir vs boosted atazanavir in patients failing a NNRTI first line regimen in an urban clinic in Kampala
  5. 76945
    “…CONCLUSIONS: The initial results from GUSTA study show that ART-regimen including MVC did not increase the incidence of adverse events or severe laboratory liver abnormalities in HIV-1-infected patients with or without HCV coinfection. …”
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    Safety and therapeutic efficacy of the switch to maraviroc+darunavir/ritonavir in HIV/HCV coinfected patients: initial results from GUSTA study
  6. 76946
    “…We also searched the metaRegister of Controlled Trials (mRCT) using 'malaria' and 'arte* OR dihydroarte*' as search terms. SELECTION CRITERIA: Randomized controlled trials comparing artemisinin‐naphthoquine combinations with established WHO‐recommended ACTs for the treatment of adults and children with uncomplicated malaria due to P. falciparum. …”
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    Artemisinin‐naphthoquine for treating uncomplicated Plasmodium falciparum malaria
  7. 76947
    “…Treatment planning employed a Monte Carlo dose calculation in SmART-Plan and creation of 0.5cm thick lead blocks custom-shaped to match DRR projections. …”
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    Treatment Planning and Delivery of Whole Brain Irradiation with Hippocampal Avoidance in Rats
  8. 76948
    por Almeida, Beverley, Campanilho‐Marques, Raquel, Arnold, Katie, Pilkington, Clarissa A., Wedderburn, Lucy R., Nistala, Kiran, Armon, Kate, Briggs, Vanja, Ellis‐Gage, Joe, Roper, Holly, Watts, Joanna, Baildam, Eileen, Hanna, Louise, Lloyd, Olivia, McCann, Liza, Roberts, Ian, McGovern, Ann, Riley, Phil, Al‐Abadi, Eslam, Ryder, Clive, Scott, Janis, Southwood, Taunton, Thomas, Beverley, Amin, Tania, Burton, Deborah, Jackson, Gillian, Van Rooyen, Vanessa, Wood, Mark, Wyatt, Sue, Browne, Michael, Davidson, Joyce, Ferguson, Sue, Gardner‐Medwin, Janet, Martin, Neil, Waxman, Liz, Foster, Helen, Friswell, Mark, Jandial, Sharmila, Qiao, Lisa, Sen, Ethan, Smith, Eve, Stevenson, Vicky, Swift, Alison, Wade, Debbie, Watson, Stuart, Crate, Lindsay, Frost, Anna, Jordan, Mary, Mosley, Ellen, Satyapal, Rangaraj, Stretton, Elizabeth, Venning, Helen, Warrier, Kishore, Almeida, Beverley, Arnold, Katie, Beard, Laura, Brown, Virginia, Campanilho‐Marques, Raquel, Enayat, Elli, Glackin, Yvonne, Halkon, Elizabeth, Hasson, Nathan, Juggins, Audrey, Kassoumeri, Laura, Lunt, Sian, Maillard, Sue, Nistala, Kiran, Pilkington, Clarissa, Simou, Stephanie, Smith, Sally, Varsani, Hemlata, Wedderburn, Lucy, Murray, Kevin, Ioannou, John, Suffield, Linda, Al‐Obaidi, Muthana, Leach, Sam, Lee, Helen, Smith, Helen, Inness, Emma, Kendall, Eunice, Mayers, David, Wilkinson, Nick, Clinch, Jacqui, Pluess‐Hall, Helen
    Publicado 2015
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    Analysis of Published Criteria for Clinically Inactive Disease in a Large Juvenile Dermatomyositis Cohort Shows That Skin Disease Is Underestimated
  9. 76949
    “…CONCLUSIONS: Treatment durability is dependent on several factors among others patient characteristics and ART guidelines. The choice of 3(rd) agent has a strong impact and significant differences between different drugs on treatment duration exist.…”
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    HIV drug therapy duration; a Swedish real world nationwide cohort study on InfCareHIV 2009-2014
  10. 76950
    “…BACKGROUND: Depression, highly prevalent in HIV, is consistently associated with worse ART adherence. Integrating CBT for depression with adherence counseling using the “Life-Steps” approach (CBT-AD) has an emerging evidence base. …”
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    Treating Depression and Adherence (CBT-AD) in Patients with HIV in Care: A Three-arm Randomized Controlled Trial
  11. 76951
    “…To examine the performance, comparison tests between the proposed RSBF and six state-of-the-art methods for ultrasound speckle removal are performed on simulated ultrasound images with various noise and speckle levels. …”
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    Rayleigh-maximum-likelihood bilateral filter for ultrasound image enhancement
  12. 76952
    “…Despite robot-led physical training could potentially improve the motor recovery of hemiparetic patients, most of the state-of-the-art studies addressing motor control learning, with artificial virtual force fields, only focused on the end-effector kinematic adaptation, by using planar devices. …”
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    Modifying upper-limb inter-joint coordination in healthy subjects by training with a robotic exoskeleton
  13. 76953
    “…METHODS: Matched plasma DBS and DPS were obtained from 200 HIV-1 infected antiretroviral treatment (ART)-experienced patients attending patient support centers in Western Kenya. …”
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    Evaluation of the performance of Abbott m2000 and Roche COBAS Ampliprep/COBAS Taqman assays for HIV-1 viral load determination using dried blood spots and dried plasma spots in Kenya
  14. 76954
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    Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121)
  15. 76955
    “…Plans were created using the TomoTherapy TPS for delivery using the Hi·Art system, the iPlan TPS for delivery using the Vero system, the Eclipse TPS for delivery using the TrueBeam system in both flattened and flattening filter free (FFF), and the MultiPlan TPS for delivery using the CyberKnife system. …”
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    Single‐fraction spine SBRT end‐to‐end testing on TomoTherapy, Vero, TrueBeam, and CyberKnife treatment platforms using a novel anthropomorphic phantom
  16. 76956
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    A Randomized Phase IIb Study of Mavrilimumab and Golimumab in Rheumatoid Arthritis
  17. 76957
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    Subcutaneous Abatacept in Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis: Results From a Phase III Open‐Label Study
  18. 76958
    “…In the framework of the third phase of the Air Quality Model Evaluation International Initiative (AQMEII3), and as contribution to the second phase of the Hemispheric Transport of Air Pollution (HTAP2) activities for Europe and North America, the impacts of a 20 % decrease of global and regional anthropogenic emissions on surface air pollutant levels in 2010 are simulated by an international community of regional-scale air quality modeling groups, using different state-of-the-art chemistry and transport models (CTMs). The emission perturbations at the global level, as well as over the HTAP2-defined regions of Europe, North America and East Asia, are first simulated by the global Composition Integrated Forecasting System (C-IFS) model from European Centre for Medium-Range Weather Forecasts (ECMWF), which provides boundary conditions to the various regional CTMs participating in AQMEII3. …”
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    Influence of anthropogenic emissions and boundary conditions on multi-model simulations of major air pollutants over Europe and North America in the framework of AQMEII3
  19. 76959
    “…We used a state-of-the-art Bayesian small-area estimation hierarchical model with latent Gaussian layers to account for space and time correlations among neighbouring counties. …”
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    Maternal mortality ratios in 2852 Chinese counties, 1996–2015, and achievement of Millennium Development Goal 5 in China: a subnational analysis of the Global Burden of Disease Study 2016
  20. 76960
    “…The multimodal results are comparable to the state-of-the-art stress recognition methods that require long-term measurements. …”
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    Instant Stress: Detection of Perceived Mental Stress Through Smartphone Photoplethysmography and Thermal Imaging
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