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  1. 102161
    “…Indeed, some patients are refractory to treatment with supplemental oxygen particularly during exercise. Theoretically these patients could benefit from an intervention that increased mixed venous oxygen content thereby ameliorating the deleterious effects of venous admixture. …”
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    Venous Admixture in COPD: Pathophysiology and Therapeutic Approaches
  2. 102162
    “…Powerful database search methods have been developed for the peptide identification, such as SEQUEST and MASCOT, which are implemented by comparing the mass spectra obtained from unknown proteins or peptides with theoretically predicted spectra derived from protein databases. …”
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    Quality assessment of tandem mass spectra using support vector machine (SVM)
  3. 102163
    “…Our solution uses a rigorous graph theoretic framework and tames the computational and space complexity using parallel computers. …”
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    Parallel short sequence assembly of transcriptomes
  4. 102164
    “…About 50% of all SNPs theoretically covered by the array could be detected in a comparative hybridization of PAO1 and PA14 genomes at high specificity (> 0.996). …”
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    Evaluation of a microarray-hybridization based method applicable for discovery of single nucleotide polymorphisms (SNPs) in the Pseudomonas aeruginosa genome
  5. 102165
    “…Subsequently, we showed theoretically that MCB leads to biased conclusions in the subsequent analyses, including estimation of allele/genotype frequencies, the measurement of HWE and association tests under various modes of inheritance relationships. …”
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    Missing call bias in high-throughput genotyping
  6. 102166
    “…Using the complex disease Systemic Lupus Erythematosus (SLE) as an example, a high-dimensional pharmacome-diseasome graph network was generated as RDF XML, and subjected to graph-theoretic proximity and connectivity analytic approaches to rank drugs versus the compendium of SLE-associated genes, pathways, and clinical features. …”
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    Inferring novel disease indications for known drugs by semantically linking drug action and disease mechanism relationships
  7. 102167
    “…This left truncation can be dealt with in non-parametric (Kaplan–Meier) and semi-parametric (Cox) time-to-event analyses, theoretically generating an unbiased hazard ratio (HR) when the proportional hazards (PH) assumption holds. …”
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    Prevalent cases in observational studies of cancer survival: do they bias hazard ratio estimates?
  8. 102168
    “…The incidence ratio of HCC : ICC : CHC (combined hepatocellular cholangiocarcinoma) in our population was 233 : 17 : 1 consistent with the theoretic ratio of hepatocyte number to cholangiocyte number in the liver. …”
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    Viral hepatitis-associated intrahepatic cholangiocarcinoma shares common disease processes with hepatocellular carcinoma
  9. 102169
    “…Sixty-three per cent of cervical cancers are theoretically preventable by HPV16/18 vaccines in Guinea; perhaps more if some cross-protection exists with HPV45.…”
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    HPV infection in women with and without cervical cancer in Conakry, Guinea
  10. 102170
    “…We postulate that dual priming could, theoretically, produce the same patterns. The resulting homopolymeric stretches associated with these insertion events may promote genomic instability and create potential target sites for future retrotransposition events.…”
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    Heads or tails: L1 insertion-associated 5' homopolymeric sequences
  11. 102171
    “…In DNA site-specific recombination catalysed by tyrosine recombinases, two pairs of DNA strands are sequentially exchanged between separate duplexes and the mechanisms that confer directionality to this theoretically reversible reaction remain unclear. The tyrosine recombinase TnpI acts at the internal resolution site (IRS) of the transposon Tn4430 to resolve intermolecular transposition products. …”
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    Control of directionality in the DNA strand-exchange reaction catalysed by the tyrosine recombinase TnpI
  12. 102172
    “…The results demonstrates that the Ab-IAP, in addition to being theoretically-based and having good psychometric properties, elicits appropriate responses.…”
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    Listening to patients: using verbal data in the validation of the Aberdeen Measures of Impairment, Activity Limitation and Participation Restriction (Ab-IAP)
  13. 102173
    “…It can also prove practically useful in providing a theoretically informed approach to sampling (by drawing on informants that are related to the technology in question) and analysis (by providing a conceptual tool and vocabulary that can form the basis for interpretations). …”
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    Actor-Network Theory and its role in understanding the implementation of information technology developments in healthcare
  14. 102174
    “…The proof-of-principle of MCPC was validated by identification of one of each possible 15 human papillomavirus types, which is the maximum target number theoretically detectable by MCPC with a 4-color channel instrument, in one reaction. …”
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    Multicolor Combinatorial Probe Coding for Real-Time PCR
  15. 102175
    “…The empirical structure of the instrument was established by confirmatory factor analysis with the first sample of parents confirming 65 statements within five theoretically conceptualized domains: information, care and cure, organization, parental participation, and professional attitude. …”
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    Construction and psychometric testing of the EMPATHIC questionnaire measuring parent satisfaction in the pediatric intensive care unit
  16. 102176
    “…BACKGROUND: Epidural analgesia with bupivacain, epinephrine and fentanyl provides excellent pain control after lumbar fusion surgery, but pruritus and motor block are frequent side effects. Theoretically epidural ropivacain combined with oral oxycodone could decrease the incidence of these side effects. …”
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    Pharmacological strategies to reduce pruritus during postoperative epidural analgesia after lumbar fusion surgery - a prospective randomized trial in 150 patients
  17. 102177
    “…The presented work applies an information theoretic framework to simultaneously analyze structure and dynamics in neuronal networks. …”
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    Information Diversity in Structure and Dynamics of Simulated Neuronal Networks
  18. 102178
    “…Balancing selection, such as negative frequency-dependent selection (NFDS), is instead suggested to establish a morph frequency cline on a geographic scale at least theoretically. Here we tested whether a large-scale smooth cline in morph frequency is established by NFDS in the female-dimorphic damselfly, Ischnura senegalensis, where andromorphs and gynomorphs are maintained by NFDS. …”
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    A geographic cline induced by negative frequency-dependent selection
  19. 102179
    “…BACKGROUND: Antimicrobials treatment of Otitis media (OM) reduces some complications, but some of chronic complications, and specially otitis media with effusion (OME), seem to increase. Theoretically the usage of nasal corticosteroid sprays may prevent this problem by reducing the local inflammation around the eustachian tube. …”
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    Effect of nasal beclomethasone spray in the treatment of otitis media with effusion
  20. 102180
    “…One mechanism driving distant LGT events is microbial transformation. Theoretically, transformative events can occur between any two species provided that the DNA of one enters the habitat of the other. …”
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    Differences in lateral gene transfer in hypersaline versus thermal environments
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