“…Although these methods will theoretically work in any context, we have able to test them only in southern and eastern Africa, where HIV epidemics are mature and generalised. …”
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“…Several mechanisms to generate this behaviour have been described theoretically, the underlying assumptions of which, however, have not been experimentally demonstrated for the EGF receptor internalization network. …”
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“…CONCLUSION: Our tests have shown that theoretically predicted contacts can be very beneficial for protein structure prediction. …”
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“…To increase awareness concerning the air pollution-related burden of disease, and to build links to health policy analyses, future research efforts should be directed towards theoretically sound and comprehensive CAP estimates with use of rich data. …”
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“…In the present study, morphological, biochemical, and physiological responses of the theoretically immortal unicellular freshwater green alga Micrasterias denticulata were examined after salt (200 mM NaCl or 200 mM KCl) and osmotic stress induced by iso-osmotic sorbitol. …”
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“…Also, the SF-space does not sample all possibilities offered by the MD-space, but often introduces very large changes along just a few deformation modes, whose number tend to a plateau as the number of related folds in the superfamily increases. CONCLUSION: Theoretically, we obtained two conclusions. First, that function restricts the access to some flexibility patterns to evolution, as we observe that when a superfamily member changes to become another, the path does not completely overlap with the physical deformability. …”
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“…As these drugs should be theoretically tailored upon featured bio-markers expressed by the patients, the clinical trial design should follow new rules based upon stronger hypotheses than those developed so far. …”
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“…Causes were understood by observation and from theoretically framed interviews with home staff, doctors and pharmacists. …”
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“…A protein-RNA interface predictor (PRIP) and the data set have been made available at . CONCLUSION: Graph-theoretic properties of residue contact maps derived from protein structures such as betweenness-centrality can supplement sequence or structure features to improve the prediction accuracy for binding residues in RNA-protein interactions. …”
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“…High genotyping accuracy was verified by 100% concordance of TSP genotypes in a blinded study with an independent genotyping method. CONCLUSION: Theoretically, TSP can be directly incorporated into the design of assays for most current single-marker SNP genotyping methods. …”
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“…The association matrix is further analyzed using a graph-theoretic technique to detect highly connected components representing interesting biological modules. …”
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“…BACKGROUND: Given the availability of full genome sequences, mapping gene gains, duplications, and losses during evolution should theoretically be straightforward. However, this endeavor suffers from overemphasis on detecting conserved genome features, which in turn has led to sequencing multiple eutherian genomes with low coverage rather than fewer genomes with high-coverage and more even distribution in the phylogeny. …”
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“…Approximately 40% of males with FXS have repeat size mosaicism and as a result, some of these individuals also have elevated levels of FMR1-mRNA which theoretically puts them at risk for FXTAS. Here, we have surveyed all of the aging patients with FXS that we have followed over the years to clarify the medical complications of aging seen in those with FXS. …”
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“…Hitherto, the empirical research fails to offer policy-makers a clear strategy on how to develop a country-specific model of demand for out-patient physician services suitable for the assessment of patient payment policies in their countries. In particular, theoretically important factors, such as provider behavior, consumer attitudes, experience and culture, and informal patient payments, are not considered. …”
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“…However, more longitudinal research and the development of theoretically-informed measures of family work are needed to advance the field.…”
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“…A fixed signal propagation scheme generates a set of possible state transitions on a discrete timescale for a given network hypothesis, reducing the number of theoretically reachable states. A likelihood score is proposed, describing the probability of measurements given the states of the proteins over time. …”
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“…BACKGROUND: The use of an interference fit wedged bone plug to provide fixation in the tibial tunnel when using bone-patellar tendon-bone autograft for anterior cruciate ligament reconstruction offers many theoretic advantages including the potential to offer a more economical and biological alternative to screw fixation. …”
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“…(failure rate: 0.9%, 95% CI 0.2-2.6%) CONCLUSION: Theoretically a diagnostic strategy using the Wells-CDR combined with a qualitative POC-D-dimer test can be used safely to exclude PE in primary care albeit with only moderate efficiency.…”
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“…BACKGROUND: Theoretically, L-type calcium channel blockers could modulate anesthetic effects. …”
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“…Nevertheless, we expect such a tracer to be developed in the next few years and maybe, theoretically, it could even be used for targeted therapy (in the form of a beta-emitter) to combat cardiovascular disease.…”
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