“…One of these pathways is the Bruton tyrosine kinase (BTK) pathway, which is essential for the production of several anti-inflammatory cytokines. Theoretically, the inhibition of BTK signaling can reduce cytokine levels and subsequent anti-inflammatory effects. …”
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“…From an item-response-theoretic point of view, this might impair the stability of item functioning in terms of item discrimination between levels of affectivity and item severity (difficulty). …”
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“…The interactions between grafted antibodies and their target, Vascular endothelial growth factor (VEGF), were theoretically investigated by molecular dynamics simulation in order to evaluate the antibodies–antigen binding behavior. …”
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“…The mechanisms of the Laser-STEM process were studied theoretically and experimentally. With the developed experimental setup, the influences of laser power and voltage on the width, depth and bottom surface roughness of the fabricated microgrooves were studied. …”
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“…In this paper, the working principle is analyzed theoretically through the partial wave method (PWM), and the gyroscopes with different numbers of PCs are also designed and studied by using the finite element method (FEM) and multiphysics simulation. …”
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“…Thus, cord blood (CB) samples could theoretically carry GdMMc. Nevertheless this has never been demonstrated. …”
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“…According to the negative antigen tests and with a theoretically probability calculation of 1/24.000, there seems no relevant risk of infection with SARS-CoV-2 in public areas. …”
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“…In this article, we use concepts relating to candidacy to enable a theoretically informed examination of experiences of access to secondary mental health services during the first wave of the COVID-19 pandemic in England. …”
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“…Our results provide insights into the ontology and system of facial expression communication and a new information-theoretic framework that can characterize its complexities.…”
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“…Vibratory (Tvib) and sustained (Tsust) torque responses to concurrent Achilles tendon vibration and neuromuscular electrical stimulation applied over the muscle belly (vib+stim) are used as indicators of motoneuron facilitation and, theoretically, persistent inward current strength. However, neuromuscular electrical stimulation (NMES) applied to the nerve trunk may potentiate motoneuronal excitability more than muscle belly NMES, yet it remains unclear whether NMES applied over the nerve evokes robust Tvib and Tsust responses when used during the vib+stim protocol. …”
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“…While significant performance boost as well as area- and power-efficiency is theoretically predicted, the realization of such analog accelerators is largely limited by non-ideal switching characteristics of crosspoint elements. …”
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“…From the model formulated, the positivity, bounded region, existence, uniqueness of the solution, the model existence of free and endemic equilibrium points, and local and global stability were theoretically proved. The basic reproduction number (R(0)) was derived by using the next-generation matrix method, which shows that, when R(0) < 1, the disease-free equilibrium is globally asymptotically stable whereas when R(0) > 1 the endemic equilibrium is globally asymptotically stable. …”
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“…However, most mass spectra in untargeted assays cannot be annotated with specific compound structures because reference mass spectral libraries are far smaller than the complement of known molecules. Theoretically predicted mass spectra might be used as a substitute for experimental spectra especially for compounds that are not commercially available. …”
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“…CONCLUSIONS: This study provides data to support the tenability of a theoretically guided framework linking pain, sleep and emotional distress. …”
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“…METHODS: We used a qualitative approach drawing on data from focus groups with key informant health and professional staff involved in the transfer of care. A theoretically-informed, semi-structured focus group guide was used to facilitate discussion and explore factors impacting on decisions made to transfer care of patients from the emergency department to the medical assessment unit. …”
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“…We will recruit participants through Facebook ads and interviews will continue until theoretic sufficiency. Using an inductive thematic analysis approach, transcripts will be coded for emergent themes by two researchers independently in QRS NVivo 12.0, with concurrent refinement of themes as interviews are completed. …”
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“…Despite the need for future studies, certain nutritional supplements may have promising advantages for basketball (long-term supplementation of nitrates for recovery), whereas others (β-alanine, sodium bicarbonate, and acute nitrate supplementation) might theoretically be regarded as not interesting for basketball, or even not recommended by the World Anti-Doping Agency (WADA) as bovine colostrum.…”
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“…We searched for primary studies reporting on ePrescribing optimization strategies and independently screened and abstracted data until saturation was achieved. Findings were theoretically and thematically synthesized taking a medicine life-cycle perspective, incorporating consultative phases with domain experts. …”
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“…We aimed to (1) examine decisional capacity for treatment in young people (aged 15 to 25 years) with first-episode psychosis (FEP), Major Depressive Disorder (MDD) and no mental disorder, and (2) determine which theoretically relevant factors are associated with, and predict decisional capacity. …”
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