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  1. 105521
    “…However, the use of poorly soluble drugs for nebulization has been inadequate, and many patients rely on large doses to achieve optimal control of their disease. Theoretically, nanotechnology with a sustained-release formulation may provide a favorable therapeutic index. …”
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    Rehydrated sterically stabilized phospholipid nanomicelles of budesonide for nebulization: physicochemical characterization and in vitro, in vivo evaluations
  2. 105522
    “…CONCLUSION: Here we propose a novel statistical framework in which existing notions of causal mediation are formalized into a hypothesis test, thus providing a standard quantitative measure of uncertainty in the form of a p-value. The method is theoretically and computationally accessible and with the provided software may prove a useful tool in disentangling molecular relationships.…”
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    Disentangling molecular relationships with a causal inference test
  3. 105523
    “…Each stage employs an information-theoretic planning algorithm to maximize information gain while minimizing experimental complexity, along with a Bayes error plan assessment framework to characterize the probability of making a correct decision once data for the plan are collected. …”
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    Planning combinatorial disulfide cross-links for protein fold determination
  4. 105524
    “…The proposed technique is theoretically sound and computationally feasible, but restricted to quantitative data obtained from closed biochemical reaction systems. …”
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    Thermodynamically consistent Bayesian analysis of closed biochemical reaction systems
  5. 105525
    “…RESULTS: With selected time, frequency and information theoretic features, the reputation-based algorithm distinguished between safe and unsafe swallowing with promising accuracy (80.48 ± 5.0%), high sensitivity (97.1 ± 2%) and modest specificity (64 ± 8.8%). …”
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    Automatic discrimination between safe and unsafe swallowing using a reputation-based classifier
  6. 105526
    “…A B-cell epitope-predicting server and molecular modeling were used to predict the residues most likely involved in IgE binding. Theoretically predicted IgE-binding regions were further confirmed by site-directed mutagenesis assays. …”
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    Identification of Critical Amino Acids in an Immunodominant IgE Epitope of Pen c 13, a Major Allergen from Penicillium citrinum
  7. 105527
    por Osada, Takuya
    Publicado 2012
    “…BF(Ab )can be determined theoretically using Doppler ultrasound by subtracting BF in the bilateral proximal femoral arteries (FAs) from BF in the upper abdominal aorta (Ao) above the coeliac trunk. …”
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    Physiological aspects of the determination of comprehensive arterial inflows in the lower abdomen assessed by Doppler ultrasound
  8. 105528
    “…A reduction in the number of segments should theoretically be possible, whilst simultaneously maintaining plan quality, provided that the reduction is accompanied by an increased number of gantry angles. …”
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    Fast IMRT by increasing the beam number and reducing the number of segments
  9. 105529
    “…BACKGROUND: The process of solutes entrapment during liposomes formation is interesting for the investigation of the relationship between the formation of compartments and the distribution of molecules inside them; a relevant issue in the studies of the origin of life. Theoretically, when no interactions are supposed among the chemical species to be entrapped, the entrapment is described by a standard Poisson process. …”
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    Characterization of the emergent properties of a synthetic quasi-cellular system
  10. 105530
    “…A set of conditions for implementation emerges from the findings of this study, which are presented as theoretically transferable propositions that have international relevance. …”
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    A pragmatic cluster randomised trial evaluating three implementation interventions
  11. 105531
    “…METHODS: We used longitudinal, case study research methods and an organizational model of innovation implementation to theoretically guide our study. Our sample consisted of three community practice settings that recently joined the National Cancer Institute’s (NCI) Community Clinical Oncology Program (CCOP) in the United States. …”
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    Implementing community-based provider participation in research: an empirical study
  12. 105532
    “…Theoretically, homogeneous environments favor the evolution of specialists whereas heterogeneous environments favor generalists. …”
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    Antagonistic Pleiotropy and Fitness Trade-Offs Reveal Specialist and Generalist Traits in Strains of Canine Distemper Virus
  13. 105533
    “…Elevated sST2 values early in the ICU course theoretically could assist therapeutic decision-making in advanced stage HF patients. …”
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    Measurement of multiple biomarkers in advanced stage heart failure patients treated with pulmonary artery catheter guided therapy
  14. 105534
    “…BACKGROUND: While the pace of commissioning of new charged particle radiation therapy facilities is accelerating worldwide, biological data pertaining to chordomas, theoretically and clinically optimally suited targets for particle radiotherapy, are still lacking. …”
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    Comparison of human chordoma cell-kill for 290 MeV/n carbon ions versus 70 MeV protons in vitro
  15. 105535
    “…METHODS/DESIGN: The trial will evaluate a theoretically and empirically sound four-unit, 12-hour education program that has been demonstrated in pilot studies to have short-term efficacy. …”
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    Sexual assault resistance education for university women: study protocol for a randomized controlled trial (SARE trial)
  16. 105536
    “…There is therefore a need to test theoretically driven interventions that focus on specific high-risk sub-groups, in which the intervention is delivered at full integrity against a credible control. …”
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    Testing the credibility, feasibility and acceptability of an optimised behavioural intervention (OBI) for avoidant chronic low back pain patients: protocol for a randomised feasibility study
  17. 105537
    por Körner, Mirjam, Wirtz, Markus A
    Publicado 2013
    “…Confirmatory factor analysis (CFA) was used to verify the theoretically assumed one-dimensional factorial structure. …”
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    Development and psychometric properties of a scale for measuring internal participation from a patient and health care professional perspective
  18. 105538
    “…METHODS: Development of the Ox-PAQ is theoretically grounded in the World Health Organization International Classification of Functioning, Disability, and Health. …”
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    The Oxford Participation and Activities Questionnaire: study protocol
  19. 105539
    “…Future projections using 2015 data, assuming 100% vaccine coverage and a true HPV causal relation of 100%, suggest that vaccines providing protection against HPV-16/18 may theoretically prevent 79% of new HPV-related ADC cases (44,702 cases annually) and vaccines additionally providing cross-protection against HPV-31/33/45 may prevent 89% of new HPV-related ADC cases (50,769 cases annually). …”
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    Estimate of the global burden of cervical adenocarcinoma and potential impact of prophylactic human papillomavirus vaccination
  20. 105540
    “…The introduction of the A. terreus cadA gene in A. niger exploits the high level of citric acid production (over 200 g per liter) and theoretically can lead to production levels of over 135 g per liter of itaconic acid in A. niger. …”
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    Expression of the Aspergillus terreus itaconic acid biosynthesis cluster in Aspergillus niger
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