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  1. 106181
    “…In addition, since 1–84-PTH is part of intact-PTH, the whole-PTH/intact-PTH ratio should not theoretically exceed 1. However, an abnormally high 1–84-PTH/intact-PTH ratio is reported in a few patients with parathyroid carcinoma, primary hyperparathyroidism and secondary hyperparathyroidism. …”
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    The whole-PTH/intact-PTH ratio is a useful predictor of severity of secondary hyperparathyroidism
  2. 106182
    “…The two connectivity measures were calculated using a common graph-theoretic framework. We also examined the spatial overlaps between these measures and possible relationships of these disrupted functional measures with autistic traits assessed by the Autism-Spectrum Quotient (AQ). …”
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    Alterations of local spontaneous brain activity and connectivity in adults with high-functioning autism spectrum disorder
  3. 106183
    “…In East Asia and Oceania the average nucleotide diversity of the loss-of-function variants was much lower than that of the variants that do not affect OCT1 function (ratio of 0.03) and was significantly lower than the theoretically expected heterozygosity (Tajima’s D = −1.64, P < 0.01). …”
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    Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1
  4. 106184
    “…CONCLUSIONS: As part of a broader programme of work, a realist review can make an important contribution to the specification of theoretically informed interventions that have the potential to improve health outcomes. …”
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    Using realist review to inform intervention development: methodological illustration and conceptual platform for collaborative care in offender mental health
  5. 106185
    “…A more satisfied and motivated health workforce should be more willing to serve in difficult areas, have lower turnover, and theoretically provide better care to patients. This paper examines the motivation, satisfaction, and correlation with clinical knowledge, of community health nurses (CHNs), a cadre of provider focused on maternal, newborn and child health in rural Ghana. …”
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    Examining domains of community health nurse satisfaction and motivation: results from a mixed-methods baseline evaluation in rural Ghana
  6. 106186
    “…Studies evaluated the quantitative impact of structural interventions for the prevention of male-to-female IPV in LMIC through (a) IPV incidence or prevalence or (b) secondary outcomes theoretically linked to IPV by study authors. After initial screening, we evaluated full text articles for inclusion and extracted data on study characteristics, outcomes, and risk of bias, using forms developed for the review. …”
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    Systematic review of structural interventions for intimate partner violence in low- and middle-income countries: organizing evidence for prevention
  7. 106187
    “…CONCLUSIONS: In this study, adopting the idea from the field of linguistics in the field of bioinformatics, we develop a new information theoretic method, PC-TraFF, for the identification of potentially collaborating transcription factors based on the idiosyncrasy of their binding site distributions on the genome. …”
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    PC-TraFF: identification of potentially collaborating transcription factors using pointwise mutual information
  8. 106188
    “…Participants will be randomised to receive either an evidence-based, theoretically informed, web-based self-management programme for people with T2DM which addresses medical, emotional, and role management, called Healthy Living for People with type 2 Diabetes (HeLP-Diabetes) or a simple information website. …”
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    HeLP-Diabetes: randomised controlled trial protocol
  9. 106189
    “…Circulating tumor DNA (ctDNA) represents a theoretically powerful biomarker for detecting otherwise occult disease. …”
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    Personalized Circulating Tumor DNA Biomarkers Dynamically Predict Treatment Response and Survival In Gynecologic Cancers
  10. 106190
    “…Nearly two-thirds of Zambians lived within 15 km of a facility theoretically capable of providing basic TOP, and one-third within 15 km of comprehensive TOP services. …”
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    Signal functions for measuring the ability of health facilities to provide abortion services: an illustrative analysis using a health facility census in Zambia
  11. 106191
    “…CONCLUSIONS: The novel information-theoretic approach and corresponding 3off2 algorithm combine constraint-based and Bayesian inference methods to reliably reconstruct graphical models, despite inherent sampling noise in finite datasets. …”
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    3off2: A network reconstruction algorithm based on 2-point and 3-point information statistics
  12. 106192
    “…CONCLUSIONS: We demonstrated the feasibility and acceptability of a large scale IPL activity where design of cases, format and assessment tasks was founded in complexity theory. This theoretically based design enabled students to achieve complex IPL outcomes relevant to future practice. …”
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    Using complexity theory to develop a student-directed interprofessional learning activity for 1220 healthcare students
  13. 106193
    “…After determining the optimal number of clusters based on information theoretic measures of variation of information and mutual information, functional parcellation patterns in both the left and the right insula were compared between the TD and ASD groups. …”
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    Altered functional organization within the insular cortex in adult males with high-functioning autism spectrum disorder: evidence from connectivity-based parcellation
  14. 106194
    “…This study aims to examine whether a theoretically designed, multi-strategy intervention was effective in increasing the implementation of a healthy canteen policy in Australian primary schools. …”
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    Effectiveness of a multicomponent intervention to enhance implementation of a healthy canteen policy in Australian primary schools: a randomised controlled trial
  15. 106195
    “…OBJECTIVE: This paper reports (1) a protocol to shortlist health apps for academic evaluation, (2) synthesis of a checklist to screen health apps for quality and reliability, and (3) a proposed method to theoretically evaluate usability of health apps, with a view towards identifying one or more apps suitable for clinical assessment. …”
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    App Chronic Disease Checklist: Protocol to Evaluate Mobile Apps for Chronic Disease Self-Management
  16. 106196
    “…CONCLUSIONS: The SD model of clinical decision-making offers a theoretically based framework to improve understanding of physicians’ behavior and the results of screening implementation trials. …”
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    A system dynamics model of clinical decision thresholds for the detection of developmental-behavioral disorders
  17. 106197
    “…The diverse host-symbiont relationships observed in the Pentatomidae will provide an ideal arena for investigating the evolution of symbiosis experimentally and theoretically. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40851-016-0061-4) contains supplementary material, which is available to authorized users.…”
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    Recurrent evolution of gut symbiotic bacteria in pentatomid stinkbugs
  18. 106198
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    Retrospective study of intravascular large B-cell lymphoma cases diagnosed in Quebec: A retrospective study of 29 case reports
  19. 106199
    “…For these outcomes, theoretically substituting 1-h/day of MVPA for 1-h/day TV-viewing was also significantly associated with lower prevalence (RR 0.91 to 0.97, all P < .05). …”
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    Leisure-time physical activity, sedentary behaviors, sleep, and cardiometabolic risk factors at baseline in the PREDIMED-PLUS intervention trial: A cross-sectional analysis
  20. 106200
    “…To help general practitioners (GPs) conduct more comprehensive medication reviews for patients with multimorbidity, we developed the theoretically-informed MultimorbiditY COllaborative Medication Review And DEcision Making (MY COMRADE) implementation intervention. …”
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    Improving medication management for patients with multimorbidity in primary care: a qualitative feasibility study of the MY COMRADE implementation intervention
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