“…The risk score was significantly associated with TIME, TIDE, stemness indexes, tumor mutation burden (TMB), immunotherapy response, and drug sensitivity. …”
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“…In addition, analysis of gene set enrichment, immune function, TMB, and TIDE showed that these differentially expressed CRLs had a wealth of related pathways and functions, and might be closely related to immune response and immune microenvironment. …”
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“…Immunotherapy may offer a more appropriate treatment option for high-risk patients due to their higher TMB and lower TIDE scores. The higher risk score may demonstrate increased sensitivity to bexarotene, cisplatin, epothilone B, and vinorelbine. …”
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“…Single gene GSEA and immune infiltration analysis revealed that CCNB1 was associated with the degree of infiltration or activation status of multiple immune cells. TIDE analysis indicated that this gene was correlated with multiple key immune checkpoint molecules and TIDE scores. …”
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“…Furthermore, a series of analyses, including GO, KEGG, Tumor Immune Dysfunction and Exclusion (TIDE), the Consensus Molecular Subtypes (CMS), were used to explore the underlying biological differences and clinical significance between these groups. …”
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“…The Tumour Immune Dysfunction and Exclusion (TIDE) analysis data showed that the 7-IRG signature had great potential for indicating the immunotherapy response in HCC patients. …”
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“…The immunophenoscore (IPS) and the tumor immune dysfunction and exclusion (TIDE) were used to estimate the clinical significance of the risk groups. …”
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“…The estimation of tumor immunotherapy response through the TIDE algorithm and prediction of innovative recommended medications on the target to immune-related risk model were also performed on the basis of the IC50 predictor. …”
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“…Meanwhile, predictions based on the TIDE algorithm support that patients with high CENPM expression have a worse response to immunotherapy. …”
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“…It also presents patient, healthcare provider, and health system rationales for re-establishing LDL-C measurement as a performance measure to improve cholesterol control in high-risk groups and to stem the rising tide of CVD morbidity and mortality, cardiovascular care disparities, and related healthcare costs.…”
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“…We point to a myriad of actions and alternatives which will help to stem the tide of climate change and its effects on the sea while, at the same time, creating a more sustainable future for humans and ecosystems alike.…”
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“…John Steinbeck – Foreword to the Third Edition of Ed Ricketts' "Tides".…”
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“…Preparatory E. coli infection induces a phase of vibriostasis in the 13-day-old egg which may be sufficient to tide the embryo over into the phase of relative insusceptibility associated with age. …”
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“…To respond to this rising tide of information, a practical, user-friendly database containing cell-lines, plasmids, vectors, selection agents, concentrations and media was created. …”
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“…In mid-2010 the Secretary-General of the United Nations launched a “Global Strategy for Women’s and Children’s Health”, also known as the “Every Woman Every Child” initiative. Has the tide now turned in favour of maternal health? The authors try to answer this question by first examining whether maternal health really missed out with respect to increased global funding and why this may have occurred. …”
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“…The practical need to understand sea level along the coasts, such as for safe navigation given the spatially variable tides, has resulted in tide gauge observations having the distinction of being some of the longest instrumental ocean records. …”
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“…In their environment, they are subjected to strong mechanical forces (current, waves, and tide), in response to which they modify rapidly and reversibly their morphology. …”
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“…The results showed that 1) shoreline erosion started when high waves with significant power in long-period (1 to 2 min.) waves reached the top of a well-developed berm with the help of rising tide; 2) the beach in the swash zone was eroded with higher elevation being more depressed, while the bottom elevation just outside the swash zone remained almost unchanged; and 3) erosion stopped in a few hours after the berm was completely eroded or the swash-zone slope became uniformly mild. …”
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“…Warming strongly impacted functioning of tide pool systems within one month, with the rate of net community production (NCP) more than doubling in warmed pools under ambient CO(2) levels relative to initial NCP values. …”
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“…Recurrent COPD exacerbations accelerate lung-function decline, worsen mortality, and consume over US$50 billion in health care spending annually. This has led to a tide of payment reforms eliciting interest in strategies reducing preventable COPD exacerbations. …”
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