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841por Nilsson, Håkan“…Among all the groups and occupations that have been affected by the global pandemic, nursing professionals stand out as having been particularly hard-pressed due to the dramatic increase in the need for their services. Given the rising tide of coronavirus disease 2019 patients who require specialized medical treatment as well as the millions of others that are lining up for vaccinations, it can be assumed that many nursing professionals have had to endure such things as longer working hours, tighter schedules, and the intensity of a work environment in which failure of care and multiple deaths are the daily fare. …”
Publicado 2021
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842“…Medical therapy continues to be the first-line therapy even as surgical techniques are improving in their safety and efficacy. To turn the tide in preventing blindness from glaucoma, attention must be focused on targeted patient education, screening, effective treatment, and addressing health disparities. …”
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843“…In the era of omics and precision medicine, offering personalized treatment could contribute to turning this tide. Here, we discuss how to structure the selection of the right patient at the right time for the right treatment. …”
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844“…It is interesting to see, however, that authoritative opinions by the Supreme Court of the United States and European regulatory agencies have somehow anticipated this tide of criticism of statistical significance testing, thus providing additional support to its demise. …”
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845“…The findings were further validated in independent EAC cohorts and potential response to ICI therapy was estimated using Tumor Immune Dysfunction and Exclusion (TIDE) and SubMap methods. Our findings suggest that EAC patients of subtype 2 with low levels of cancer-associated fibroblasts, tumor associated macrophages (TAMs), and MDSCs in the tumor microenvironment may benefit from PD-1 blockade therapy, while patients of subtype 1 are more responsive to chemotherapy or combination therapy. …”
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846“…Tumor Immune Dysfunction and Exclusion (TIDE) and immunophenoscore (IPS) analyses revealed that STAD patients with different MRGS scores had different reactions to immunotherapy. …”
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847“…Although the case did not fit within the usual UAE guidelines, the treatment was done to tide over the crisis as a temporary method to control severe hemorrhage. …”
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848por Ulrich, Johann F., Gräfe, Melina S., Dhiman, Seema, Wienecke, Paul, Arndt, Hans-Dieter, Wichard, Thomas“…Thallusin, a highly biologically active, phytohormone-like and bacterial compound-inducing morphogenesis of the green tide-forming macroalga Ulva (Chlorophyta), was determined in bacteria and algae cultures. …”
Publicado 2022
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849“…The developed tool, the Team Information Decision Engine (TIDE), relies on an innovative preference learning method along with an aggregation procedure that permits combining scores by individual analysts into aggregated scores. …”
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850“…Moreover, the immunotherapeutic response and chemotherapy drug sensitivity were compared between the two groups to guide precise treatment. The TIDE database was applied to predict the possibility of immune escape in the TCGA-HNSC cohort. …”
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851“…Additionally, the Tumor Immune Dysfunction and Exclusion (TIDE) algorithm was used to predict immunotherapy response and identify potential immune beneficiaries. …”
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852“…Corresponding results were confirmed in GEO dataset. Finally, TIDE analysis uncovered that the IRL classifier may be effectually predict the clinical response of immunotherapy in LSCC. …”
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853por Fang, Yutong, Liu, Junpeng, Zhang, Qunchen, She, Chuanghong, Zheng, Rongji, Zhang, Rendong, Chen, Zexiao, Chen, Chunfa, Wu, Jundong“…The ICGs PDCD1, CTLA4, LAG3, SIGLEC15, and TIGIT were negatively corrected with VDAC1 expression in BC. TIDE scores between the low and high expression groups showed no difference. …”
Publicado 2022
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854por Wang, Changjing, Tang, Yujie, Ma, Hongqing, Wei, Sisi, Hu, Xuhua, Zhao, Lianmei, Wang, Guiying“…The level of immune checkpoint-related genes and TIDE score was significantly lower in subtype A than that in subtype B, indicating that subtype A might benefit from immune checkpoint inhibitors. …”
Publicado 2022
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855“…There is a crucial need for novel antibiotics to stem the tide of antimicrobial resistance, particularly against difficult to treat gram-negative pathogens like Acinetobacter baumannii-calcoaceticus complex (ABC). …”
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856“…In this study, heat transport across the ASF is investigated using eddy- and tide-resolving, process-oriented simulations. It is found that freshening of the fresh coastal waters leads to increased shoreward heat flux, which implies a positive feedback in a warming climate: Increased meltwater will increase shoreward heat transport, causing further melt of ice shelves.…”
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857por Ma, Chao, Zhang, Mengmeng, Ding, Yi, Xue, Yan, Wang, Hongju, Li, Pengfei, Wu, Dapeng“…Lithium–sulfur batteries (LSBs) with a high energy density have been regarded as a promising energy storage device to harness unstable but clean energy from wind, tide, solar cells, and so on. However, LSBs still suffer from the disadvantages of the notorious shuttle effect of polysulfides and low sulfur utilization, which greatly hider their final commercialization. …”
Publicado 2023
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858por Setiawan, Ichsan, Haditiar, Yudi, Syukri, Muhammad, Ismail, Nazli, Rizal, Syamsul“…The results of the model correlated with the Tide Model Driver data obtained, and the simulation results indicated the current in February 2019 is different than in August. …”
Publicado 2023
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859por Islamova, Renata, Yanshin, Nikolay, Zamyatkina, Elizaveta, Gulk, Ekaterina, Zuy, Ekaterina, Billig, Susan, Birkemeyer, Claudia, Tarakhovskaya, Elena“…To our knowledge, this study is the first attempt to draft a detailed biochemical network underneath the complex physiological processes, conferring the successful survival of this organism in the harsh conditions of the high intertidal zone of the polar seas. We considered the tide-induced changes in relative water content, stress markers, titratable acidity, pigment, and phlorotannin content, as well as the low molecular weight metabolite profiles (GC-MS-based approach) in Pelvetia thalli. …”
Publicado 2023
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860por Huang, Shuaishuai, Cai, Congbo, Zhou, Kena, Wang, Xue, Wang, Xue, Cen, Dong, Weng, Guobin“…Patients with low expression of DLAT had a lower survival rate, worse clinical prognosis, stronger immune cell infiltration and expression of immunosuppressive points, and higher tumor immune dysfunction and exclusion (TIDE) scores. Conclusions: DLAT was identified as an independent prognostic factor in ccRCC and was closely related to the prognosis and immune responses of patients with ccRCC.…”
Publicado 2023
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