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1441“…The prognosis, clinicopathological features, immune infiltration, gene expression at immune checkpoints, tumor immune dysfunction and exclusion (TIDE) score, and chemotherapy resistance of OS were analyzed among clusters. …”
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1442“…Furthermore, transcriptomic data from TCGA datasets, IHC and flowcytometry from our cohort were used to confirm the findings. Kaplan-Meier and TIDE scores were also used for prognostic analysis and ICB responses. …”
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1443por Fang, Yujie, Zhao, Jing, Guo, Xu, Dai, Yunfeng, Zhang, Hao, Yin, Fanxin, Zhang, Xiaoxu, Sun, Chenxi, Han, Zequan, Wang, Hecheng, Han, Yanshuo“…Subsequently, we performed an immunological bioinformatics analysis of the model from multiple perspectives using the CIBERSORT algorithm, ESTIMATE algorithm, and TIDE algorithm to verify the accuracy of the model. …”
Publicado 2022
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1444por Ji, Hang, Liu, Zhihui, Wang, Fang, Sun, Haogeng, Wang, Nan, Liu, Yi, Hu, Shaoshan, You, Chao“…Thus, the responsiveness of samples in the MRGPI-high group to immune checkpoint inhibitors (ICI) was detected by algorithms, including Tumor Immune Dysfunction and Exclusion (TIDE) and Submap. In contrast, the MRGPI-low group had favorable outcome, was less immune active and insensitive to ICI. …”
Publicado 2022
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1445por Zhang, Xunlang, Wu, Xinhui, Huang, Huang, Du, Kangming, Nie, Yingying, Su, Peiyuan, Li, Yuefei“…Results showed that Cluster1 patients had a lower TIDE score and were more sensitive to immunotherapy in both TCGA and combined GEO cohorts. …”
Publicado 2022
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1446“…BACKGROUND: Improving the health status of users through the use of digital health information systems has drawn the attention of practitioners and academics under the tide of the digital revolution, specifically in the time of global pandemic of COVID-19, and as a result, online medical consultation has developed rapidly. …”
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1447por Gou, Qiheng, Liu, Zijian, Xie, Yuxin, Deng, Yulan, Ma, Ji, Li, Jiangping, Zheng, Hong“…A low TRG score showed a better response to immunotherapy in TNBC by TIDE (Tumor Immune Dysfunction and Exclusion) analysis and sensitivity to multiple drugs in GDSC (Genomics of Drug Sensitivity in Cancer) analysis and a significant therapeutic advantage in patients in the three immunotherapy cohorts. …”
Publicado 2022
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1448“…And the Tumor Immune Dysfunction and Exclusion (TIDE), the Cancer Immunome Atlas (TCIA), and Genome of Drug Sensitivity in Cancer (GDSC) databases further demonstrated that high-risk patients have a positive response to immunotherapy and have lower IC50 values for drugs targeting cell cycle, PI3K/mTOR, WNT, and RTK related signaling pathways. …”
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1449“…The single-sample gene set enrichment analysis (ssGSEA) was chosen to perform gene set variation analysis (GSVA), and the GSEABase package was selected to detect the immune and inflammatory infiltration profiles. The TIDE and IC(50) evaluation were used to estimate the effectiveness of clinical treatment on KIRC. …”
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1450“…The present study also analyses whether ownership of ration cards and contacts with the party in power locally helped the household to tide over the crisis. The data was collected through a two-phase primary survey undertaken in January-March 2020 (pre-lockdown period) and October-November 2020 (post-lockdown period). …”
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1451por Ye, Chenyang, Lu, Yier, Yuan, Zhijun, Mi, Mi, Qi, Lina, Yuan, Ying, Weng, Shanshan“…In addition, higher FANCD2 expression was related to a higher tumor immune dysfunction and exclusion (TIDE) score, indicating lower responder rates to cancer immunotherapeutics. …”
Publicado 2022
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1452“…Methylation and Tumor Immune Dysfunction and Exclusion (TIDE) analyses revealed that PLAU upregulation was most likely caused by hypomethylation and that high PLAU expression may be associated with tumor immune evasion in HNSCC, respectively.…”
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1453“…The IRS model was also used in assessing clinicopathological features, such as microsatellite instability (MSI) status, epithelial-mesenchymal transition (EMT) status, clinical stages, tumor mutational burden (TMB), and tumor immune dysfunction and exclusion (TIDE) scores. Low IRS scores were associated with high immune checkpoint gene expression. …”
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1454por Deng, Lin, Mi, Jinglin, Ruan, Xiaolan, Zhang, Guozhen, Pan, Yufei, Wang, Rensheng“…CIBERSORT, ESTIMATE, and TIDE tools were applied to estimate immune characteristics. …”
Publicado 2022
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1455por Sun, Tao, Yang, Zhibo, Chen, Jun, Li, Yang, Wang, Jing, Wang, Xiya, Tang, Xuexi, Xiao, Hui“…IMPORTANCE Periodic water loss caused by the tide is an important environmental factor that is faced by intertidal macroalgae, but the impact of periodic water loss on the epiphytic bacterial communities associated with macroalgae is still unknown. …”
Publicado 2022
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1456por Su, Jia-Qi, Tian, Xi, Xu, Wen-Hao, Anwaier, Aihetaimujiang, Ye, Shi-Qi, Zhu, Shu-Xuan, Wang, Yue, Gu, Jun, Shi, Guo-Hai, Qu, Yuan-Yuan, Zhang, Hai-Liang, Ye, Ding-Wei“…The immunotherapy response was assessed using the TIDE database. Single-cell RNA databases evaluated the PYCARD expression of immune cells. …”
Publicado 2022
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1457“…Phascolosoma esculenta, an economically important species inhabiting the high tide areas of the intertidal zone, is particularly sensitive to water pollution. …”
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1458“…Patients with the C1 subtype exhibited upregulated pathways with better liver function, downregulated cancer-related pathways, lower cancer stem cell scores, lower Tumor Immune Dysfunction and Exclusion scores (TIDE), different ferroptosis status, and better prognosis compared with the patients with the C2 subtype. …”
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1459“…Immunotherapeutic response was inferred via tumor mutation burden (TMB), Tumor Immune Dysfunction and Exclusion (TIDE), and Submap methods. Finally, we developed a LASSO model for recurrence prediction. …”
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1460“…Furthermore, the risk score was linked to immune checkpoint expression (including PD-L1), the tumor immune dysfunction and exclusion (TIDE) score, and chemotherapy sensitivity. We also created an accurate nomogram to increase the clinical applicability of the risk score. …”
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