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  1. 1501
    “…RESULTS: CRISPR/Cas9 could delete exon-3 of the PDCD1 gene in the engineered cells based on the tracking of indels by decomposition (TIDE) and interference of CRISPR edit (ICE) sequencing analysis reports. …”
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    Reversing T Cell Exhaustion by Converting Membrane PD-1 to Its Soluble form in Jurkat Cells; Applying The CRISPR/Cas9 Exon Skipping Strategy
  2. 1502
    “…Increased expression of proteoglycan and type II collagen and decreased expression of type I collagen were revealed at the surface of the defect, and an elevated level of type X collagen at the newly developed tide mark region. Conversely, the control group showed osteoarthritic alterations. …”
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    Regeneration of injured articular cartilage using the recombinant human amelogenin protein
  3. 1503
    por Zhang, Hai-Bo, Pan, Jian-Yan, Zhu, Tao
    Publicado 2023
    “…Patients’ response to immunotherapy and other antineoplastic drugs was predicted by the TIDE algorithm and GDSC tool, respectively. Results: We identified 127 disulfidptosis-related lncRNAs, and a prognostic model that consists eight of them (KTN1-AS1, AL365181.3, MANCR, LINC01352, AC090559.1, AC093673.1, AP001094.3, and MHENCR) was established and verified. …”
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    A disulfidptosis-related lncRNA prognostic model to predict survival and response to immunotherapy in lung adenocarcinoma
  4. 1504
    “…We hypothesized, based on the interpretive facies analysis, that the Chittagong Tripura fold belt region's Upper Surma Group underwent three interrelated depositional settings (wave-dominated shallow marine, tide-dominated shallow marine, and fluvio-deltaic distributary).…”
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    High-resolution lithostratigraphy and reconnaissance sedimentology of Changotaung structure, Chittagong Tripura fold belt, Bengal Basin, Bangladesh
  5. 1505
    por Plamondon, K, Dixon, J
    Publicado 2023
    “…Plamondon et al. Turning the tide on inequity through systematic equity action-analysis. …”
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    Integrating Equity Considerations in an International Pandemic Instrument
  6. 1506
    “…Analyses of ESTIMAT, immune function, Tumor Immune Dysfunction and Exclusion (TIDE) scores, Immune cell Proportion Score (IPS), and immune checkpoint genes between high- and low-risk groups were performed, and then analyses of drug sensitivity to screen for sensitive anticancer drugs in high-risk groups. …”
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    Construction and validation of a novel prognostic model of neutrophil‑related genes signature of lung adenocarcinoma
  7. 1507
    “…Finally, we compared the immune-related molecules between GPR-TME subgroups and resorted to the Tumor Immune Dysfunction and Exclusion (TIDE) for immunotherapy response prediction. The mRNA and protein expression of GPR-related gene P2RY14 were, respectively, validated by RT-PCR in clinical samples and HPA database. …”
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    The combined signatures of G protein-coupled receptor family and immune landscape provide a prognostic and therapeutic biomarker in endometrial carcinoma
  8. 1508
    “…We further assessed the value of TGFB1 in predicting immunotherapy response using TIDE and real-world immunotherapy datasets. TGFB1 showed a hematologic-tissue-specific expression pattern both across normal tissues and cancer types. …”
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    Comprehensive characterization of TGFB1 across hematological malignancies
  9. 1509
    “…Non-alcoholic fatty liver disease (NAFLD) has emerged as a global epidemic intricately linked to the rising tide of obesity and metabolic syndrome. This comprehensive review delves into the complex web of relationships between NAFLD, liver fibrosis, and subclinical atherosclerosis, shedding light on their interplay, shared risk factors, and clinical implications. …”
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    Uncovering the Cardiovascular Threat: A Comprehensive Examination of Liver Fibrosis and Subclinical Atherosclerosis in Non-alcoholic Fatty Liver Disease
  10. 1510
    por He, Mingdong, Yu, Jun, Chen, Shaohua, Mi, Hua
    Publicado 2023
    “…MATERIAL AND METHODS: We systematically analyzed the raw data from The Cancer Genome Atlas (TCGA), Tumor Immune Estimation Resource (TIMER), and Tumor Immune Dysfunction and Exclusion (TIDE) databases. Initially, we investigated the differences in CD48 expression between pan-cancer and adjacent normal tissues. …”
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    A Systematic Immune and Prognostic Analysis of CD48 Interaction with Tumor Microenvironment in Pan-Cancer
  11. 1511
    “…Naturally desiccated plants were collected during low tide and studied for morphological changes, oxidative burst induction, biomolecule oxidation, antioxidant responses, and photosynthetic status. …”
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    Tolerance to oxidative stress induced by desiccation in Porphyra columbina (Bangiales, Rhodophyta)
  12. 1512
    por Sullivan, R
    Publicado 2007
    “…One has only to contrast a paper on the treatment of solid epithelial cancers written by Henri Tagnon and colleagues in 1966 (Eur J Cancer 2 51–7) with the myriad of chemotherapeutic approaches at the oncologists disposal today. Inevitably, as the tide of research has risen so it has bought the flotsam and jetsam of regulations and policies. …”
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    Policy challenges for cancer research: a call to arms
  13. 1513
    “…BACKGROUND: Crassostrea gigas accumulates paralytic shellfish toxins (PST) associated with red tide species as Gymnodinium catenatum. Previous studies demonstrated bivalves show variable feeding responses to toxic algae at physiological level; recently, only one study has reported biochemical changes in the transcript level of the genes involved in C. gigas stress response. …”
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    Genomics Study of the Exposure Effect of Gymnodinium catenatum, a Paralyzing Toxin Producer, on Crassostrea gigas' Defense System and Detoxification Genes
  14. 1514
    “…In the 5.5 mM U-(13)C-glucose plus 2.7 mM 2-(13)C/(15)N-glycine emergence treatment used to simulate 12 h of “low tide”, oysters accumulated more (13)C-labeled metabolites, including both anaerobic glycolytic and aerobic Krebs cycle intermediates. …”
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    Fluxomics of the Eastern Oyster for Environmental Stress Studies
  15. 1515
    “…More aggressive public health measures are required to stem the tide.…”
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    The Prevalence of Chronic Kidney Disease in Apparently Healthy Retired Subjects in Asaba, Nigeria
  16. 1516
    “…RESULTS: Within-season abundance patterns were related to climatic variables (i.e. temperature, rainfall, tide heights, relative humidity and photoperiod) that varied according to the mosquito species in question. …”
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    Climatic effects on mosquito abundance in Mediterranean wetlands
  17. 1517
    “…BACKGROUND: Medicine-related burden is an increasingly recognized concept, stemming from the rising tide of polypharmacy, which may impact on patient behaviors, including nonadherence. …”
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    Validation of an instrument to measure patients’ experiences of medicine use: the Living with Medicines Questionnaire
  18. 1518
    “…Summer ETM bacterial communities varied depending on coastal upwelling or downwelling conditions and on the sampling site location with respect to tidal intrusion during the previous neap tide. In contrast to ETM, whole (>0.2 μm) and free‐living (0.2–3 μm) assemblages of non‐ETM waters were similar to each other, indicating that particle‐attached (>3 μm) non‐ETM bacteria do not develop a distinct community. …”
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    Factors affecting the bacterial community composition and heterotrophic production of Columbia River estuarine turbidity maxima
  19. 1519
    “…The cumulative occurrence rates of genotypic resistance to ETV were not significantly different between CHB patients with prior nucleos(t)tide analogues (NA) exposure (NA experienced, n=56) and NA naïve patients (n=202, P=0.823 by log rank comparison). …”
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    Clinical characteristics of patients with chronic hepatitis B who developed genotypic resistance to entecavir: Real-life experience
  20. 1520
    “…We first conducted a mesocosm experiment to investigate the effect of fragment age and species on settlement (i.e., remains on the substrate in a rising tide) and subsequently establishment (i.e., rooting in substrate) rates. …”
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    Unlikely Nomads: Settlement, Establishment, and Dislodgement Processes of Vegetative Seagrass Fragments
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