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  1. 2961
    “…Demographic characteristics were collected from each victim, and comparisons of death trends before and after the pandemic were conducted using the interrupted time series analysis. The absolute number of deaths and proportion of deaths from each type of drug/poisoning were used for the analyses. …”
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    Impact of COVID-19 on poisoning-related mortality in Iran: An interrupted time series study
  2. 2962
    “…In phase 3, the effects on the total number and severity of reported PAEs will be evaluated using Poisson regression with interrupted time-series analysis over a 2-year period, while users’ engagement, adherence, process evaluation and cost-effectiveness will be evaluated using quarterly surveys and interviews. …”
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    Development and evaluation of a data-driven integrated management app for perioperative adverse events: protocol for a mixed-design study
  3. 2963
    “…To examine change in data completeness, we conducted an interrupted time series analysis using multivariable logistic mixed-effects regression. …”
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    Effects of primary healthcare reform on routine health information systems (RHISs): a mixed-methods study in Lesotho
  4. 2964
    “…Trends in monthly and quarterly proportions of total ARB prescribing were analysed for individual ARBs using descriptive statistics and interrupted time series analysis. The rate of switching to an alternative ARB was analysed before and after the recalls. …”
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    A collaborative study of the impact of N-nitrosamines presence and ARB recall on ARB utilization – results from IQVIA™ Disease Analyzer Germany
  5. 2965
    “…DESIGN: Retrospective observational study using interrupted time series analysis to identify changes in hospitalisation rate and case fatality rate (CFR) by epidemic wave. …”
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    Changes in the epidemiological profile of SARS-CoV-2-positive individuals in Mexico across pandemic waves as an explanation of fatality reduction: a retrospective observational study
  6. 2966
    “…The aim of this study was to carry out the time series analysis of PM(2.5), PM(10) and TSP in the Ciuc basin for the period 2010–2019, in order to decipher the main characteristics of air pollution in this region. …”
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    Temporal evolution of PM(2.5), PM(10), and total suspended particles (TSP) in the Ciuc basin (Transylvania) with specific microclimate condition from 2010 to 2019
  7. 2967
    “…An interrupted time-series analysis for the period between 2014 and 2020 was performed in two groups: young (age 18–29) and other adults (30+) to ascertain the trends in the monthly incidence of hospitalization related to psychoactive substance intoxication (opiates, cocaine, benzodiazepines, psychostimulants, alcohol and cannabis). …”
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    General hospital admissions in young and middle-aged people who use psychoactive substances: Impact of Covid-19 lockdowns
  8. 2968
    “…Quantitative phase/analyses included: monthly total and average of the BUN test for six hospitals (medicine programme and two EDs) were compared pre initiative and post initiative; a cost avoidance calculation and an interrupted time series analysis were performed (participants were divided into two groups: high (>50%) and low (<50%) BUN test reduction based on these findings). …”
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    Factors of a physician quality improvement leadership coalition that influence physician behaviour: a mixed methods study
  9. 2969
    “…DESIGN, SETTING, AND PARTICIPANTS: Interrupted time series analysis from January 1, 2018, to June 30, 2022. …”
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    Racial, Ethnic, and Sex Differences in Methadone-Involved Overdose Deaths Before and After the US Federal Policy Change Expanding Take-home Methadone Doses
  10. 2970
    “…We used interrupted time series analysis to examine the impact of the first COVID-19–related state of emergency in Alberta on the number of cancer diagnoses. …”
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    Impact of the COVID-19 pandemic on cancer diagnoses, stage and survival in Alberta
  11. 2971
    “…METHOD: Performing a time series analysis from 1996 to 2020, we applied a negative binomial regression model to evaluate the link between the incidence of melioidosis in Townsville and various weather variables. …”
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    The effect of climate on melioidosis incidence in Townsville, Australia: a dry tropical region
  12. 2972
    “…We then conducted an interrupted time series analysis to assess the differences between testing periods. …”
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    HIV testing in jails: Comparing strategies to maximize engagement in HIV treatment and prevention
  13. 2973
    “…We grouped monthly AU (defined daily doses [DDD]/1000 patient-days) into broad-spectrum β-lactams, carbapenems, and colistin and used interrupted time-series analysis to compare AU during pre- and post-pandemic onset. …”
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    Antibiotic Consumption During the Coronavirus Disease 2019 Pandemic and Emergence of Carbapenemase-Producing Klebsiella pneumoniae Lineages Among Inpatients in a Chilean Hospital: A Time-Series Study and Phylogenomic Analysis
  14. 2974
    “…RESULTS: A total of 1893 differentially expressed genes were identified. Time series analysis indicated that at around 6 weeks, the development of chicken abdominal fat was extensively regulated by the TGF-β signaling pathway, Wnt signaling pathway, and PPAR signaling pathway. …”
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    Transcriptome analysis reveals FABP5 as a key player in the development of chicken abdominal fat, regulated by miR-122-5p targeting
  15. 2975
    “…Finally, we selected monocytes for mimetic time series analysis and analyzed the expression changes of oxidative stress genes with the mimetic time series axis, in which the expression of JUN, TXN, and IL-1β differed with the change of cell status. …”
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    Uncovering the potential role of oxidative stress in the development of periodontitis and establishing a stable diagnostic model via combining single-cell and machine learning analysis
  16. 2976
    “…Controlled interrupted time series analysis was used to evaluate changes in COPD-specific hospitalizations, emergency department (ED) visits, physician visits, and claims for pulmonary function test. …”
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    Pharmacists’ chronic disease management in chronic obstructive pulmonary disease: Effect on health services utilization
  17. 2977
    “…In this study, we identified changes in gene expression that contribute to the activation of M cells and immunocompetent cells after intranasal vaccination of mice with antigen-CVP using a time-series analysis of spatial transcriptomics data. The results facilitated the identification of the cell types that are activated during the initial induction of nasal mucosal immunity.…”
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    Application of spatial transcriptomics analysis using the Visium system for the mouse nasal cavity after intranasal vaccination
  18. 2978
    “…Pharmacy claims were assessed for the presence of nitrates, insulin, rosiglitazone, other antidiabetic therapy, or no antidiabetic therapy supply on days 30, 60, 90, and 180 after the rejected/paid claim. A time-series analysis using rosiglitazone claims for all health plan members from January 2008 through December 2009 was used to evaluate the impact of the PA on rosiglitazone utilization overall. …”
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    Rosiglitazone Prior Authorization Safety Policy: A Cohort Study
  19. 2979
    “…A univariate analysis was conducted using the Fisher’s Exact test and interrupted time series analysis to determine differences between midazolam administration and PACU times, with interruption occurring at tablet implementation. …”
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    The Effect of Computer Tablets on the Need for Medical Anxiolysis in Children in an Ambulatory Surgical Center
  20. 2980
    “…Dynamic changes were identified in genes and metabolites by time-series analysis. The genes and metabolites involved in photosynthesis and purine metabolism were altered in light treatment, and the expression of genes and metabolites associated with carotenoid biosynthesis, sphingolipid metabolism, MAPK signaling pathway, and plant hormone signal transduction pathway were induced by dark treatment. …”
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    Integrative transcriptome and metabolome analysis reveals the mechanisms of light-induced pigmentation in purple waxy maize
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