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  1. 3201
    “…We compared VRE incidence and antibiotic days of therapy (DOT) before and after the intervention using interrupted time-series analysis with segmented Poisson regression with auto-correlation. …”
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    280. The Impact of a Revised Neutropenic Fever Guideline on Vancomycin-Resistant Enterococcus Rates in Pediatric Oncology Patients
  2. 3202
    “…Ciprofloxacin use was significantly reduced postintervention [26.9% (29/108) vs. 39.8% (43/108); P = 0.043] as well as Guidance MS approvals [9.03% (87/963) vs. 17.72% (188/1,061); P = 0.000001]. Interrupted time series analysis of this intervention was not associated with a significant change in the rates of ciprofloxacin use. …”
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    214. Antimicrobial Usage and Outcomes following Laboratory Suppression of Antimicrobial Susceptibility Results for Pseudomonas aeruginosa in Sputum Cultures
  3. 3203
    “…METHODS: Interrupted time series analysis evaluated the effectiveness of the two-staged sports programmes. …”
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    The effectiveness and cost-effectiveness of a complex community sport intervention to increase physical activity: an interrupted time series design
  4. 3204
    “…Our analysis methods will combine machine learning methods for detecting transportation mode use and physical activity, use temporal Geographic Information Systems to quantify changes to urban intervention exposure, and apply analytic methods for natural experiment studies including interrupted time series analysis. DISCUSSION: INTERACT aims to advance the evidence base on population health intervention research and address challenges related to big data, knowledge mobilization and engagement, ethics, and causality. …”
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    INTERACT: A comprehensive approach to assess urban form interventions through natural experiments
  5. 3205
    “…METHODS: We conducted a nationwide daily time-series analysis in 272 main Chinese cities from 2013 to 2015. …”
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    Associations between Coarse Particulate Matter Air Pollution and Cause-Specific Mortality: A Nationwide Analysis in 272 Chinese Cities
  6. 3206
    “…Quantitative data will be collected during baseline, intervention, and sustainability periods and analyzed using time series analysis. The primary outcome is the number of individuals completing tuberculosis preventive therapy by the end of the two-year intervention phase. …”
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    Bridging the knowledge-practice gap in tuberculosis contact management in a high-burden setting: a mixed-methods protocol for a multicenter health system strengthening study
  7. 3207
    “…Blood circulating (c-)microRNAs (miRs), c-proteasome, c-mitochondrial DNA, and cytokines were assessed by real-time quantitative PCR or ELISA tests. Time series analysis was performed (i.e., before flight and after landing) at 1 and 15 d of recovery (R+1 and R+15, respectively). …”
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    Recovery from 6-month spaceflight at the International Space Station: muscle-related stress into a proinflammatory setting
  8. 3208
    “…We performed interrupted time series analysis to estimate differences in the change of near miss per delivery rate and case fatality rates. …”
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    Effect of the competency-based Helping Mothers Survive Bleeding after Birth (HMS BAB) training on maternal morbidity: a cluster-randomised trial in 20 districts in Tanzania
  9. 3209
    “…DESIGN, SETTING, AND PARTICIPANTS: Cohort study using an interrupted time series analysis of TIRF prescriptions to Medicare Part D beneficiaries nationwide from 2010 to 2014. …”
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    Association of a Risk Evaluation and Mitigation Strategy Program With Transmucosal Fentanyl Prescribing
  10. 3210
    “…In this work, we propose an unsupervised probabilistic framework that combines time series analysis of self-reported symptoms collected by the Influenzanet platforms and performs an algorithmic detection of groups of symptoms, called syndromes. …”
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    Unsupervised extraction of epidemic syndromes from participatory influenza surveillance self-reported symptoms
  11. 3211
    “…Simple descriptive statistics and interrupted time-series analysis were used to assess changes in uninsured visits over time and after the implementation of insurance provisions in 2014. …”
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    US Emergency Department Visits and Hospital Discharges Among Uninsured Patients Before and After Implementation of the Affordable Care Act
  12. 3212
    “…An interrupted time series analysis was performed to describe the association between FDA safety warnings and the use of varenicline and NRT. …”
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    Varenicline and Nicotine Replacement Use Associated With US Food and Drug Administration Drug Safety Communications
  13. 3213
    “…Pharmacologically treated diabetes cases were obtained through a population-based registry of the Hungarian National Health Insurance Fund. Time series analysis was used to evaluate the changing patterns of the incidence and prevalence for type 1 and type 2 diabetes covering a 16-year period. …”
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    Changes in the incidence and prevalence of type 1 and type 2 diabetes among 2 million children and adolescents in Hungary between 2001 and 2016 – a nationwide population-based study
  14. 3214
    “…DESIGN, SETTING, AND PARTICIPANTS: This interrupted time series analysis and cross-sectional study examined immediate level and slope changes in monthly outcomes after prescribing limit implementation in Massachusetts and Connecticut. …”
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    Association of State Opioid Duration Limits With Postoperative Opioid Prescribing
  15. 3215
    “…We conducted an interrupted time series analysis to assess the impact of the 10/20 policy on the levels of and trends in coverage for 4+ ANC contacts among all women; early ANC initiation and use of public facility-based care among 1+ ANC users; and use of public primary care facilities and receipt of good content, or quality, of ANC among users of public facilities. …”
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    Examining user fee reductions in public primary healthcare facilities in Kenya, 1997–2012: effects on the use and content of antenatal care
  16. 3216
    “…This quality improvement study compared a 20-month preintervention baseline period with a 16-month post-intervention period ending on December 31, 2017, using the health system’s electronic medical record. Interrupted time series analysis was used to assess the effect of the intervention on opioid prescribing. …”
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    Reducing Opioid Overprescribing by Educating, Monitoring and Collaborating with Clinicians: A Quality Improvement Study
  17. 3217
    “…METHODS: An epidemiologic time series analysis of online search trends relating to the COVID-19 pandemic was performed from January 9, 2020, to April 6, 2020. …”
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    Correlations of Online Search Engine Trends With Coronavirus Disease (COVID-19) Incidence: Infodemiology Study
  18. 3218
    “…We performed an ecological time series analysis to evaluate the association between daily air pollutants and outpatient visits. …”
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    Ambient particulate matter and biomass burning: an ecological time series study of respiratory and cardiovascular hospital visits in northern Thailand
  19. 3219
    “…METHODS AND FINDINGS: The study was designed using an interrupted time series analysis using routinely collected data from two hospital networks (four maternity hospitals) at 6-month intervals during reform activity (January 2014 to December 2016). …”
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    Evaluation of systems reform in public hospitals, Victoria, Australia, to improve access to antenatal care for women of refugee background: An interrupted time series design
  20. 3220
    “…We use independent sample t-test and single-group interrupted time series analysis (ITSA) to compare the number of inpatients per month in the three MAs, including three county and 10 township hospitals before and after the reform. …”
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    Comparison of inpatient distribution amongst different medical alliances in a county: a longitudinal study on a healthcare reform in rural China
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