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  1. 3221
    “…The changes were assessed using a time series analysis with linear regression and prescription trends were plotted over time. …”
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    Long-term trends in the prescription of antidiabetic drugs: real-world evidence from the Diabetes Registry Tyrol 2012–2018
  2. 3222
    “…The importance of cas3 in controlling virulence was corroborated in a Galleria mellonella infection model, where the presence of the Δcas3 mutant resulted in a statistically significant increase in mortality of G. mellonella. A time-series analysis of transcription patterning during infection showed that G. mellonella elicited very different immune responses to the wild-type and the Δcas3 mutant strains and revealed a rearrangement of association in coexpression networks. …”
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    Virulence of the Pathogen Porphyromonas gingivalis Is Controlled by the CRISPR-Cas Protein Cas3
  3. 3223
    “…Poisson regression and a controlled, interrupted time series analysis were used to model trends in wait-listing rates by race/ethnicity. …”
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    Association of State Medicaid Expansion With Racial/Ethnic Disparities in Liver Transplant Wait-listing in the United States
  4. 3224
    “…We performed an interrupted time series analysis to determine the impact of the COVID-19 outbreak on outcomes and critical pathway parameters. …”
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    Modification of Acute Stroke Pathway in Korea After the Coronavirus Disease 2019 Outbreak
  5. 3225
    “…An interrupted time series analysis measured changes in guideline concordance. …”
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    45. Antimicrobial Stewardship for Urinary Tract Infection in Three Emergency Departments Across a Health System
  6. 3226
    “…We used interrupted time series analysis with segmented regression to examine the effect of our intervention on the difference in proportion of HCP positive for SARS-COV2 (using logistic regression) and HAI (using Poisson regression). …”
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    LB-16. Association Between Universal Face Shield in a Quaternary Care Center and Reduction of SARS-COV2 Infections Among Healthcare Personnel and Hospitalized Patients
  7. 3227
    “…Expedited roll-out of an intervention may vitiate a step-wedge cluster design, but the intervention can still be studied using a time-series analysis. Assuming that there is some value in time series analyses, this is better than no evaluation at all. …”
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    An opportunistic evaluation of a routine service improvement project to reduce falls in hospital
  8. 3228
    por Unger, Joseph M., Xiao, Hong
    Publicado 2021
    “…An interrupted time-series analysis with Poisson regression was used. RESULTS: We examined 62,252 trial activations. …”
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    The COVID-19 pandemic and new clinical trial activations
  9. 3229
    “…DESIGN: Interrupted time-series analysis based on an open cohort study. SETTING: A representative sample of 402 Australian general practices contributing data to the MedicineInsight database. …”
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    Trends in long-term opioid prescriptions for musculoskeletal conditions in Australian general practice: a national longitudinal study using MedicineInsight, 2012–2018
  10. 3230
    “…We conducted a time series analysis on 4023 PubMed abstract of plant genetics-based articles which focus on 4 major Solanaceous crops (tomato, potato, eggplant and capsicum), to determine that the networks contained both previously known and contemporaneously unknown leads to subsequently discovered biological phenomena relating to flesh color. …”
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    Extracting knowledge networks from plant scientific literature: potato tuber flesh color as an exemplary trait
  11. 3231
    “…We evaluated the performance of the proposed algorithm in a simulation study, as well as in a 20-year time-series analysis of extreme heat and emergency department visits for 12 outcomes in the Atlanta metropolitan area. …”
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    Using logic regression to characterize extreme heat exposures and their health associations: a time-series study of emergency department visits in Atlanta
  12. 3232
    “…MAIN OUTCOMES AND MEASURES: The primary outcome was number of new pregnancy episodes initiated within the health care system and use of those episodes to project birth volumes. Interrupted time series analysis was used to assess the degree to which COVID-19 societal changes may have factored into pregnancy episode volume. …”
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    Use of Electronic Medical Records to Estimate Changes in Pregnancy and Birth Rates During the COVID-19 Pandemic
  13. 3233
    “…Structural break in the time series analysis was done by using Chow test. Results  There was 53.8% reduction in number of neurological emergencies visiting ED during lockdown (22.1 visits vs. 10.2 visits per week, p = 0.001), significantly affecting rural population ( p = 0.004). …”
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    Non-COVID Neurological Emergencies: A Silent Killer Going Unnoticed during COVID-19 Pandemic
  14. 3234
    “…DESIGN, SETTING, AND PARTICIPANTS: This population-based cohort study with an interrupted time-series analysis used linked health administrative data bases for residents of all nursing homes (N = 630) in Ontario, Canada. …”
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    Comparison of Medication Prescribing Before and After the COVID-19 Pandemic Among Nursing Home Residents in Ontario, Canada
  15. 3235
    “…FINDINGS: Based on the time-series analysis using daily hospitalization data, 28,560 LRI cases, 54,600 CHD cases, and 23,989 stroke cases are attributable to ambient PM(2.5) in the 74 cities during the study period, and the related attributable expenses are 220 million CNY (US$ 32.9 million) for LRI, 458 million CNY (US$ 68.5 million) for CHD, and 410 million CNY (US$ 65.8 million) for stroke, respectively. …”
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    Short-Term Ambient Particulate Air Pollution and Hospitalization Expenditures of Cause-Specific Cardiorespiratory Diseases in China: A Multicity Analysis
  16. 3236
    “…An interrupted time series analysis assessed the impact on maternal, neonatal, child, sexual and reproductive health services from July 2019 to December 2020. …”
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    Indirect effects of COVID-19 on maternal, neonatal, child, sexual and reproductive health services in Kampala, Uganda
  17. 3237
    “…The trial registration number is NCT03518151. Interrupted time series analysis showed that increases in store-level sales of fruits and vegetables were greater in intervention stores than predicted at 3 (1.71 standard deviations (SDs) (95% CI 0.45, 2.96), P = 0.01) and 6 months follow-up (2.42 SDs (0.22, 4.62), P = 0.03), equivalent to approximately 6,170 and approximately 9,820 extra portions per store, per week, respectively. …”
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    Altering product placement to create a healthier layout in supermarkets: Outcomes on store sales, customer purchasing, and diet in a prospective matched controlled cluster study
  18. 3238
    “…METHODS: Interrupted time series analysis was performed to estimate the magnitude of decline in the number of STI reported confirmed cases - chlamydia, gonorrhoea, syphilis, and lymphogranuloma venereum- in Catalonia since lockdown with historical data, from March 13th to August 1st 2020, comparing the observed with the expected values. …”
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    The impact of the COVID-19 pandemic on Sexually Transmitted Infections surveillance data: incidence drop or artefact?
  19. 3239
    “…However, little is known about the dynamics of ITH, owing to the lack of time-series analysis at the single-cell level. Mouse models that recapitulate cancer development are useful for controlled serial time sampling. …”
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    Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model
  20. 3240
    “…We previously reported increased Aboriginal interpreter uptake and decreased rates of self-discharge during implementation of a 12-month hospital-based intervention. Interrupted time-series analysis showed sudden increase and up-trending improvement in interpreter use, and a corresponding decrease in self-discharge rates, during a 12-month intervention period (April 2018—March 2019) compared with a 24-month baseline period (April 2016 –March 2018). …”
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    Does improved interpreter uptake reduce self-discharge rates in hospitalised patients? A successful hospital intervention explained
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