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3por Pauwels, Laurens, Barbero, Gemma Fernández, Geerinck, Jan, Tilleman, Sofie, Grunewald, Wim, Pérez, Amparo Cuellar, Chico, José Manuel, Bossche, Robin Vanden, Sewell, Jared, Gil, Eduardo, García-Casado, Gloria, Witters, Erwin, Inzé, Dirk, Long, Jeff A., De Jaeger, Geert, Solano, Roberto, Goossens, Alain“…Here we show that the JAZ proteins recruit the Groucho/Tup1-type co-repressor TOPLESS (TPL)8 and TPL-related proteins (TPRs) through a previously uncharacterized adaptor protein, designated Novel INteractor of JAZ (NINJA). …”
Publicado 2010
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5por Ke, Jiyuan, Ma, Honglei, Gu, Xin, Thelen, Adam, Brunzelle, Joseph S., Li, Jiayang, Xu, H. Eric, Melcher, Karsten“…TOPLESS (TPL) and TOPLESS-related (TPR) proteins comprise a conserved family of plant transcriptional corepressors that are related to Tup1, Groucho, and TLE (transducin-like enhancer of split) corepressors in yeast, insects, and mammals. …”
Publicado 2015
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6“…Here we report proteins identified after conducting Tandem Affinity Purification (TAP) of the TOPLESS (TPL) corepressor from Arabidopsis. We generated transgenic plants harboring TPL fused to the GS-TAG, “Boosting tandem affinity purification of plant protein complexes” (Van Leene et al., 2008) [1]. …”
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7por Leydon, Alexander R, Wang, Wei, Gala, Hardik P, Gilmour, Sabrina, Juarez-Solis, Samuel, Zahler, Mollye L, Zemke, Joseph E, Zheng, Ning, Nemhauser, Jennifer L“…The plant corepressor TOPLESS (TPL) is recruited to a large number of loci that are selectively induced in response to developmental or environmental cues, yet the mechanisms by which it inhibits expression in the absence of these stimuli are poorly understood. …”
Publicado 2021
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8“…Here we show that BZR1 represses target genes by recruiting the Groucho/TUP1-like transcriptional corepressor TOPLESS (TPL). Specific deletion or mutation of an evolutionarily conserved ERF-ASSOCIATED AMPHIPHILIC REPRESSION (EAR) motif at the C-terminus abolishes BZR1’s abilities to regulate gene expression and cell elongation, but these defects are rescued by TPL fusion to the EAR motif-mutated BZR1. …”
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9por Garner, Christopher M., Spears, Benjamin J., Su, Jianbin, Cseke, Leland J., Smith, Samantha N., Rogan, Conner J., Gassmann, Walter“…Therefore, to explore potential connections between SRFR1 and TOPLESS family members, we took a genetic approach that examined the effect of each TOPLESS member in the srfr1 mutant background. …”
Publicado 2021
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10por Graeff, Moritz, Straub, Daniel, Eguen, Tenai, Dolde, Ulla, Rodrigues, Vandasue, Brandt, Ronny, Wenkel, Stephan“…This motif enables miP1a/b microProteins to interact with TOPLESS/TOPLESS-RELATED (TPL/TPR) proteins. Interaction of CO with miP1a/b/TPL causes late flowering due to a failure in the induction of FLOWERING LOCUS T (FT) expression under inductive long day conditions. …”
Publicado 2016
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11por Navarrete, Fernando, Gallei, Michelle, Kornienko, Aleksandra E., Saado, Indira, Khan, Mamoona, Chia, Khong-Sam, Darino, Martin A., Bindics, Janos, Djamei, Armin“…Through its native ethylene-responsive element binding factor-associated amphiphilic repression (EAR) motif, Nkd1 binds to the transcriptional co-repressors TOPLESS/TOPLESS-related (TPL/TPRs) and prevents the recruitment of a transcriptional repressor involved in hormonal signaling, leading to the de-repression of auxin and jasmonate signaling and thereby promoting susceptibility to (hemi)biotrophic pathogens. …”
Publicado 2021
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12por Darino, Martin, Chia, Khong‐Sam, Marques, Joana, Aleksza, David, Soto‐Jiménez, Luz Mayela, Saado, Indira, Uhse, Simon, Borg, Michael, Betz, Ruben, Bindics, Janos, Zienkiewicz, Krzysztof, Feussner, Ivo, Petit‐Houdenot, Yohann, Djamei, Armin“…Jsi1 interacts with several members of the plant corepressor family Topless/Topless related (TPL/TPR). Jsi1 expression in Zea mays and Arabidopsis thaliana leads to transcriptional induction of the ethylene response factor (ERF) branch of the jasmonate/ethylene (JA/ET) signaling pathway. …”
Publicado 2021
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13por Gryffroy, Lore, Ceulemans, Evi, Manosalva Pérez, Nicolás, Venegas-Molina, Jhon, Jaramillo-Madrid, Ana Cristina, Rodrigues, Savio D., De Milde, Liesbeth, Jonckheere, Veronique, Van Montagu, Marc, De Coninck, Barbara, Vandepoele, Klaas, Van Damme, Petra, Goossens, Alain“…Here, by means of TurboID-mediated proximity labeling in tomato (Solanum lycopersicum) hairy roots, we identified the repressor proteins TOPLESS (TPL) and Novel Interactor of JAZ (NINJA) as direct interactors of RolB. …”
Publicado 2023
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14por Harvey, Sarah, Kumari, Priyanka, Lapin, Dmitry, Griebel, Thomas, Hickman, Richard, Guo, Wenbin, Zhang, Runxuan, Parker, Jane E., Beynon, Jim, Denby, Katherine, Steinbrenner, Jens“…Here we characterize the interaction between an RxLR effector, HaRxL21 (RxL21), and the Arabidopsis transcriptional co-repressor Topless (TPL). We establish that RxL21 and TPL interact via an EAR motif at the C-terminus of the effector, mimicking the host plant mechanism for recruiting TPL to sites of transcriptional repression. …”
Publicado 2020
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15por Ma, Honglei, Duan, Jingbo, Ke, Jiyuan, He, Yuanzheng, Gu, Xin, Xu, Ting-Hai, Yu, Hong, Wang, Yonghong, Brunzelle, Joseph S., Jiang, Yi, Rothbart, Scott B., Xu, H. Eric, Li, Jiayang, Melcher, Karsten“…TOPLESS are tetrameric plant corepressors of the conserved Tup1/Groucho/TLE (transducin-like enhancer of split) family. …”
Publicado 2017
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16“…Meanwhile, the Q protein could physically interact with the bread wheat transcriptional co‐repressor TOPLESS (TaTPL). Specifically, the N‐terminal ethylene‐responsive element binding factor‐associated amphiphilic repression (EAR) (LDLNVE) motif but not the C‐terminal EAR (LDLDLR) motif of Q protein mediates its interaction with the CTLH motif of TaTPL. …”
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17“…A topless potential energy with inverse square root is introduced to solve the energy spectrum equations and the bound state wave functions of the static Schrödinger equation by coordinate variation and combining the extraordinary coefficients of the confluent hypergeometric functions. …”
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18por Hao, Yanwei, Wang, Xinyu, Li, Xian, Bassa, Carole, Mila, Isabelle, Audran, Corinne, Maza, Elie, Li, Zhengguo, Bouzayen, Mondher, van der Rest, Benoit, Zouine, Mohamed“…Members of the TOPLESS gene family emerged recently as key players in gene repression in several mechanisms, especially in auxin perception. …”
Publicado 2014
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