Mostrando 2,181 - 2,200 Resultados de 147,287 Para Buscar '"translator"', tiempo de consulta: 0.44s Limitar resultados
  1. 2181
    “…The type 1 human immunodeficiency virus is a good paradigm to understand the great diversity of translational control. Indeed, scanning, leaky scanning, internal ribosome entry sites, and adenosine methylation are used by ribosomes to translate spliced and unspliced HIV-1 mRNAs, and some require specific cellular factors, such as the DDX3 helicase, that mediate mRNA export and translation. …”
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  2. 2182
    por Keiper, Brett D.
    Publicado 2019
    “…Cellular mRNAs in plants and animals have a 5′-cap structure that is accepted as the recognition point to initiate translation by ribosomes. Consequently, it was long assumed that the translation initiation apparatus was built solely for a cap-dependent (CD) mechanism. …”
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  3. 2183
  4. 2184
    “…[Purpose] To establish a standardized sonographic approach to quantify anterior translation of the mandibular condyle during mouth opening by examining the reliability of image acquisition and processing, and to understand how anterior condylar translation contributes to mouth opening. …”
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  5. 2185
  6. 2186
    “…Occasionally, stop codons in the mRNA are bypassed and translation continues into the untranslated region (3′-UTR). …”
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  7. 2187
    “…A final section focusses specifically on the benefits of trial-by-trial analysis of responding during such tasks, and the implications of such analyses for the translation of findings to clinical studies.…”
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  8. 2188
    “…A robust biomedical informatics infrastructure is essential for academic health centers engaged in translational research. There are no templates for what such an infrastructure encompasses or how it is funded. …”
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  9. 2189
  10. 2190
    por Jönsson, Bengt, Sullivan, Richard
    Publicado 2019
    “…Health economics is an integrated aspect of all phases of mission‐oriented translational cancer research and should be considered an intrinsic component of any study aimed at improving outcomes for patients and intervention costs. …”
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  11. 2191
    por Berns, Anton
    Publicado 2019
    “…Innovative collaborative research in this translational trajectory requires the participation of well‐resourced and well‐organised institutions that are committed to high scientific and ethical standards. …”
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  12. 2192
  13. 2193
    “…The third step involves building these animal models from both a translational and a reverse translational perspective in order to gain critical insight into the etiologies of specific cognitive impairments and the development of their early physiological and behavioral biomarkers. …”
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  14. 2194
    “…We further extended these results to human brains and found that tau pathologically interacts with ribosomal protein S6 (rpS6 or S6), a crucial regulator of translation. Consequently, protein synthesis under translational control of rpS6 was reduced under tauopathic conditions in Alzheimer’s disease brains. …”
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  15. 2195
    “…Throughout the review, we highlight opportunities to drive the field forward by bridging new knowledge of polyelectrolytes with existing translational challenges.…”
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  18. 2198
    “…However, mRNA translation is not always perfect, and errors in the amino acid composition may occur. …”
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  19. 2199
    por Heo, Kyung-Sun
    Publicado 2019
    “…The small ubiquitin-related modification molecule (SUMO), one of the post-translational modification molecules, is involved in a variety of cellular functions where it regulates protein activity and stability, transcription, and cell cycling. …”
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  20. 2200
    por Jaafar, Zane A., Kieft, Jeffrey S.
    Publicado 2018
    “…Viruses must co-opt the cellular translation machinery to produce progeny virions. Eukaryotic viruses have evolved a variety of ways to manipulate the cellular translation apparatus, in many cases using elegant RNA-centred strategies. …”
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