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  1. 2381
    por Zhang, Feng, Voytas, Daniel F
    Publicado 2019
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    Modulating gene translational control through genome editing
  2. 2382
    “…This review describes those features and pathways crucial to the clinical translation of nanomedicine and highlights considerations for early-stage product development. …”
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    Current hurdles to the translation of nanomedicines from bench to the clinic
  3. 2383
    “…Premature termination codon (PTC) mutations account for approximately 10% of pathogenic variants in monogenic diseases. Stimulation of translational readthrough, also known as stop codon suppression, using translational readthrough-inducing drugs (TRIDs) may serve as a possible therapeutic strategy for the treatment of genetic PTC diseases. …”
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    Stop Codon Context-Specific Induction of Translational Readthrough
  4. 2384
    “…Introduction: Fibromyalgia (FM) translates into a reduction in the quality of life of people who suffer from it, being a chronic disease of unknown etiology. …”
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    Spanish Translation and Cultural Adaptation of the Fibromyalgia Knowledge Questionnaire
  5. 2385
    “…In thyroid cancer, the role of liquid biopsy in either diagnosis or prognosis is beginning to translate from the lab to the clinic. In this review, we describe the evolution of liquid biopsies in detecting CTC, ctDNA and miRNA in thyroid cancer patients, together with its limitations and future directions in clinical practice.…”
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    Translational Utility of Liquid Biopsies in Thyroid Cancer Management
  6. 2386
    “…Here, we discuss the current knowledge and provide translational novel considerations regarding its clinical detection and targeting to improve the outcome of patients with non-small-cell lung carcinoma of all stages. …”
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    Hypoxia in Lung Cancer Management: A Translational Approach
  7. 2387
    “…PURPOSE: The present study aimed to translate the Targeting the individual's Aetiology of Nocturia to Guide Outcomes Questionnaire (TANGO) into the Greek language to create TANGO-Gr. …”
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    Translation and Validation of the TANGO Nocturia Screening Tool into Greek
  8. 2388
    por Ahn, Matae, Wang, Lin-Fa
    Publicado 2021
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    Translation from bats to humans beyond infectious diseases
  9. 2389
    por Favorito, Luciano A.
    Publicado 2021
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    Editorial Comment: Translational research in urology: nutricion and prostate
  10. 2390
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    Assessing the application of human-centered design to translational research
  11. 2391
    “…In this review, we discuss the translational aspects of NIR-PIT especially in HNSCC, and potential future applications.…”
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    Near infrared photoimmunotherapy for cancers: A translational perspective
  12. 2392
    por Ketema, Ezra B., Lopaschuk, Gary D.
    Publicado 2021
    “…However, the underlying causes of these metabolic alterations remain poorly understood. Recently, post-translational acetylation-mediated modification of metabolic enzymes has emerged as one of the important regulatory mechanisms for these metabolic changes. …”
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    Post-translational Acetylation Control of Cardiac Energy Metabolism
  13. 2393
    “…Collectively, this study suggests that image translation by the convolutional network can predict the localization of functionally related proteins, and the convolutional network might be used to describe the relationships between the proteins by their localization.…”
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    Translation of Cellular Protein Localization Using Convolutional Networks
  14. 2394
    por Hopkins, Chelsea, Qin, Ling
    Publicado 2021
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    Continued improvement of translational medicine – A cohesive approach
  15. 2395
    “…METHODS: Children and adolescents between 10 and 16 years (N = 240, 166 females, mean age = 13.05 ± 1.70 years), recruited in chiropractic practices and schools, completed the G-YSQ (translated according to scientific guidelines) and the KIDSCREEN-10 (assessing health-related quality of life) at three time points. …”
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    Translation and validation of the German version of the Young Spine Questionnaire
  16. 2396
    “…Mechanistically, TDP-43 LLPS ablation increased its association with PABPC4, RPS6, RPL7, and other translational factors. The physical interactions between TDP-43 and translational factors relies on a motif, the deletion of which abolished the impact of LLPS-deficient TDP-43 on translation. …”
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    Translational regulation in the brain by TDP-43 phase separation
  17. 2397
    “…Characteristics of the translation product are often used in translation process research as predictors for cognitive load, and by extension translation difficulty. …”
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    Comparing the Effect of Product-Based Metrics on the Translation Process
  18. 2398
    Publicado 2021
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    Communications to the International Sarcopenia Translational Research Conference 2021
  19. 2399
    “…In addition, it provides insights into the challenges faced by surgeons and scientists to develop new therapies and deliver the results of translational research to improve patient care.…”
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    Advances in Skin Tissue Bioengineering and the Challenges of Clinical Translation
  20. 2400
    “…We discover thousands of genes that have dynamic changes at the translational level and pervasive translational regulation in a developmental stage-specific manner with specific biological functions. …”
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    Widespread translational control regulates retinal development in mouse
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